Ozone / Oxidative Therapy

Ozone / Oxidative Therapy: Overview

Thousands of physicians worldwide use ozone in their medical practice.  Specific therapeutic applications of ozone include the treatment of vascular disease such as stroke, obstructive arteriopathy, venous insufficiency, cancer, acute and chronic viral diseases, ulcers, infected wounds, gangrenes, burns, inflammatory bowel disease such as Crohn's disease, ulcerative colitis and spinal disc problems.  Ozone is also excellent for topical treatment of infections, wounds, ulcers and burns, especially those that are difficult to heal.

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It has been estimated that over ten million people (primarily in Germany, Russia and Cuba) have been given bio-oxidative therapies over the past seventy years to treat over fifty different diseases.  In some cases, bio-oxidative therapies are administered alone, while in others they are used in addition to traditional medical procedures (such as surgery or chemotherapy) or as adjuncts to alternative health practices.

Ozone (O3) is an energized form of oxygen with extra electrons.  It forms the protective ozone layer around the planet, yet becomes a pollutant when mixed with hydrocarbons and nitrogen oxide from automobile and factory emissions.  Because ozone is an effective bactericide and fungicide, over 2,000 municipalities around the world purify their drinking water with ozone.

Hydrogen peroxide (H202) is made up of two hydrogen atoms and two oxygen atoms.  A powerful oxidizer, hydrogen peroxide kills bacteria, virii and fungi.  A 3% solution of hydrogen peroxide is commonly used to externally disinfect wounds.  Higher concentrations of hydrogen peroxide are used extensively in the agricultural, food and chemical industries as a disinfectant, water purifier and bleaching agent.  It is also a common ingredient in contact lens cleaners, eye drops and mouthwashes.

Hydrogen peroxide has long been used medically as a disinfectant, antiseptic and oxidizer, but has only recently been found to successfully treat a wide variety of human diseases with a minimum of harmful side-effects.

History; Source

Bio-oxidative therapies have been around for a long time.  They were first reported by Dr. T.H. Oliver in The Lancet in 1920 and since that time they have been studied in major medical research centers throughout the world.

Hydrogen peroxide occurs naturally in rain and snow, from atmospheric ozone, and in mountain streams where rushing water is continuously aerated.  Hydrogen peroxide is formed due to this rapid agitation, and kills harmful microbes when present.  Mother's milk contains a high amount of H2O2, especially colostrum, the first milk secreted after birth, which activates the newborns immune systems, and key to many other metabolic processes.  Under conditions of optimum health, H2O2 is produced by the body's immune system in whatever amounts are needed to quickly destroy invading hostile organisms.

Function; Why it is Recommended

The use of hydrogen peroxide and ozone in medicine is based on the belief that the accumulation of toxins in the body is normally burnt up by the process of oxidation, a process wherein a substance is changed chemically because of the effect of oxygen on it.  Oxidation breaks the toxins down and eliminates them from the body.

Bio-oxidative therapies are used to provide the body with active forms of oxygen intravenously or through the skin.  Once in the body, the hydrogen peroxide or ozone breaks down into various oxygen subspecies which contact anaerobic virii and microbes (virii and microbes that have the ability to live without air), as well as diseased or deficient tissue cells.  It oxidizes these cells while leaving the healthy cells alone.  When the body becomes saturated with these special forms of oxygen, it reaches a state of purity wherein disease microorganisms are killed, while the underlying toxicity is oxidized and eliminated.

According to Frank Shallenberger, MD, author of The Principles and Applications of Ozone Therapy, bio-oxidative therapies affect the human body in the following ways:

  • They stimulate the production of white blood cells, which are necessary to fight infection.
  • Ozone and hydrogen peroxide are virucidal (virus-killing).
  • They increase oxygen and hemoglobin disassociation, thus increasing the delivery of oxygen from the blood to the cells.
  • Ozone and hydrogen peroxide are anti-neoplastic, which means that they inhibit the growth of new tissues such as tumors.
  • They oxidize and degrade petrochemicals.
  • They increase red blood cell membrane flexibility and effectiveness.
  • Bio-oxidative therapies increase the production of interferon and Tumor Necrosis Factor, which the body uses to fight infections and cancers.
  • They increase the efficiency of the anti-oxidant enzyme system, which scavenges excess free radicals in the body.
  • They accelerate the citric acid cycle, which is the main cycle for the liberation of energy from sugars.  This then stimulates basic metabolism.
  • Bio-oxidative therapies increase tissue oxygenation, thus bringing about patient improvement.

Hydrogen peroxide is involved in all of life's vital processes, and must be present for the immune system to function properly.  The cells in the body that fight infection (known as granulocytes) produce hydrogen peroxide as a first line of defense against invading organisms like parasites, virii, bacteria and yeast.

Apart from conditions listed below, ozonated olive oil can also be used for fistulae, leg ulcers, bed sores, gingivitis, vulvovaginitis, bee stings, insect bites and other skin-related problems.


The five primary ways to administer medical ozone, sometimes in combination, include:

  1. Autohemotherapy (remove blood from the body, ozonate it, return it by injection into muscle or vein)
  2. Rectal insufflation (like an enema, but with ozonated oxygen)
  3. Ozone "bagging" body, except for head, or body part placed in a bag, then filled with ozonated air)
  4. Ozonated oil (used externally, and sometimes internally)
  5. Injection into/near painful joints.

The most common form of hydrogen peroxide therapy used by doctors is as an intravenous drip.  For use at home, some individuals add a cup of 35% food grade hydrogen peroxide to a bathtub of warm water and soak for 20 to 30 minutes as the hydrogen peroxide is absorbed through the skin.  Others drink a glass of water to which several drops or more of food or reagent grade hydrogen peroxide have been added.  Although there have been reports of improved health with oral use, physicians like Dr. Farr believed that taking hydrogen peroxide orally could have a corrosive and tumorous effect on the stomach and small intestine and advised against using it.  There is animal research supporting this caution.

Instructions for oral use – use under supervision

Food grade (35%) H2O2 is used internally since the common over-the-counter USP 3% H2O2 contains small amounts of chemical stabilizers and other impurities.  It can still be used if food-grade is unavailable.

A typical starting dosage is one ounce of 0.5% (170 dilution of 35%) H2O2 in water although some people find they need to start with less.  As the peroxide contacts pathogens in the stomach it liberates free oxygen and some people experience slight nausea while the reaction is occurring.  The dosage is increased by an ounce per day, up to five ounces on the fifth day, then finally up to 5 ounces 3 times daily for a week (or until disease is no longer present).  The dosage is then tapered back down to nothing over a five week period.

An alternate dosage regimen uses 3 drops of 35% H2O2 in at least 4 ounces (120ml) of water 3 times daily, which is then increased by a drop per dose, per day, up to 25 drops per dose in extreme cases.  Candidiasis victims should start at one drop per dose, and build their tolerance gradually.  Some find that the taste is bleach-like and unpleasant, and may wish to chase it with plain water or fruit juice.  Citrus juices, in particular, mask the taste fairly well.

Hydrogen Peroxide Bath Directions

  • Add 6 to 8 ounces of food grade hydrogen peroxide (35%) to a hot bath.  Over-the-counter hydrogen peroxide (3%) can also be used, but requires about 3 quarts for an equivalent amount.  Up to 2 cups of food grade hydrogen peroxide can be used per bath, but this dose is usually reserved for active infection fighting.
  • Stir the bath water to make sure the hydrogen peroxide is thoroughly mixed.
  • Remain in the tub for 30 minutes and avoid getting water in your eyes.
  • For individuals with sensitive skin it may be best to start with 2 to 4 ounces to see if there will be a negative reaction.  If not, the remainder can be added to the trial bath or a full dose taken on subsequent baths.
  • Once benefit has been established, a bath frequency of 3 times per week is common.  Adverse reactions are rare.


Although both ozone and hydrogen peroxide are highly toxic in their purified state, they have been found to be both safe and effective when diluted to therapeutic levels for medical use.  When administered in prescribed amounts by a qualified practitioner, the chances of experiencing adverse reactions to bio-oxidative therapies are extremely small.  For example, a German study on 384,775 patients evaluating the adverse side effects of over five million medically-administered ozone treatments found that the rate of adverse side-effects was only 0.0007 per application.  This figure is far lower than any other type of medical therapy.

Be careful in handling high concentrations of hydrogen peroxide as they can irritate the skin and induce vomiting when ingested.

On This Page

Ozone / Oxidative Therapy:

Ozone / Oxidative Therapy can help with the following:


Premature/Signs of Aging

There are many testimonies of the anti-aging benefits of oxidation therapies as simple as the hydrogen peroxide bath.


Allergic Rhinitis / Hay Fever

Many allergy sufferers claim that Hyperbaric Oxygen Therapy (HBOT) greatly relieves their allergy symptoms.  The high levels of oxygen provided by this treatment promote optimal functioning at the cellular level, reducing the inflammatory process and allowing the body to heal itself.  Preliminary studies have also shown that levels of IgE (the antibody that leads to an immune response) are decreased by HBOT, which may reduce the magnitude of the allergic response.  More research is needed.


Coronary Disease / Heart Attack

If infection is present, selected antibiotic therapies such as UV blood irradiation or oxidative therapies (H2O2/ozone) can reduce the risk associated with certain infections.

Dental / Oral

Susceptibility To Cavities

It was originally reported in September of 2002 that Edward Lynch of the Royal Victoria Hospital's School of Dentistry had developed a technique known as ozone dental therapy that allows saliva to help decayed teeth repair themselves naturally.  Within 10 years, ozone therapy had come of age and it now has a wide range of applications in almost every field of dentistry.

The bad bacteria that cause decay are slow workers and ozone not only kills these bugs, but also primes the tooth surface so that remineralizing can begin.  Human saliva is "supersaturated" with calcium and phosphates, which allow teeth to heal and cavities to close.

Ozone is a natural gas composed of three atoms of oxygen, with the chemical symbol O3.  Ozone does pose a danger, so this technology uses a method to ensure that the gas goes exactly where it is needed, not into the patient's mouth.  A small rubber cap is fitted over the tooth and the hole is hit by a concentrated blast of ozone from a clinical ozone generator for up to 40 seconds.  It is then suctioned out.

Back in 2002, the treatment had already been used in more than 100 test facilities around the world; the success rate was around 99%, and there were no reports of treated teeth re-decaying.  For patients, the treatment meant that for most cavities there would be no need for drilling – eliminating the noise, smell and discomfort that it can cause.  100% of patients who had the treatment said they would want it again if they needed another filling.  It could be used as a preventative measure as well, with children never needing fillings if they continued treatment.  Healthy teeth would need to be treated every six months or so, perhaps as part of a routine checkup.

Since then, there have been significant improvements to this already successful technology.  Full-arch trays covering all the teeth and gums are filled with ozone for a short period of time every few months as a preventive measure.  Ozone now offers some of the best results in wound healing and the treatment of internal tooth infections, abscesses, lesions, and deep, infected crevices.


Ulcerative Colitis

Rectal insufflation of ozone can hasten tissue repair and kill bacteria that may be slowing the healing process.

Gastric/Peptic/Duodenal Ulcers

Cuban doctors are using capsules filled with ozonated oil to treat gastroduodenal ulcers, gastritis, giardia and peptic ulcers.


Cubans are using capsules filled with ozonated oil to treat gastroduodenal ulcers, gastritis, giardia and peptic ulcers.


Capsules filled with ozonated oil and used as suppositories, or rectal insufflation of ozone gas have proven useful in treating inflamed hemorrhoids.  Ozone can kill bacteria which may slow tissue healing.

IBS (Irritable Bowel Syndrome)

Proponents of ozone therapy claim that it kills bad bacteria in the gut, helps to neutralize excess acid, balances the metabolic rate, improves vitamin and mineral absorption, and thereby reduces symptoms of IBS such as diarrhea and constipation.


Vaginitis/Vaginal Infection

Vaginal infections lead to a reduction in beneficial vaginal microflora.  A study showed that the vaginas of 47 of 53 healthy women, but only 30 of 102 women with bacterial vaginosis, contained predominantly L. acidophilus and L. plantarum.  Additionally it showed that 72% of the healthy women and 77% of those with vaginosis produced hydrogen peroxide for its bactericidal effect.  Vaginal douching with 14 cup of 3% hydrogen peroxide mixed in 2 cups of water will reduce the population causing the infection.  Vaginal implants of ozone gas will have this beneficial effect also.

Both of these therapies should be followed with some kind of microflora repopulation either orally or by implant.



Athletes Foot

Ozonated olive oil is used against fungal infections in general, including athlete's foot.

Herpes Simplex Type I

Dr. R. Mattassi of Italy in his 1982 study found that 24 out of 27 people with Herpes simplex stayed in remission with up to a 3 year follow-up.  He also showed that all lesions went into remission after a maximum of 5 ozone injections.

Fungal Skin / Nail Infection

Ozonated olive oil is used for fungal infections in general.

Infectious Mononucleosis - Mono

According to doctors who have used ozone in mononucleosis, resolution of symptoms is accomplished more quickly.

Epstein-Barr Virus (EBV)

The inactivation of viral particles by ozone may take place by a variety of mechanisms which range from direct physical-chemical effects to a more indirect immunological effect.  Virii coated by a lipid glycoprotein envelope such as Epstein-Barr are vulnerable to the influence of ozone by its intense oxidizing properties.

Cytomegalovirus (CMV) Infection

Using ozone at home requires an aggressive program to reverse active CMV.

Shingles (Herpes Zoster)

At the Center of Medical and Surgical Research in Havana, 15 adult patients suffering from herpes zoster were treated with injections of ozone/oxygen for a period of 15 days.  All patients were completely symptom-free after the treatment and follow-up examinations a year later showed no relapse.

Lab Values

High White Blood Cell Count

Various ozone therapies have been used successfully to fight both known and hidden bacterial, viral and fungal infections.


Rheumatoid Arthritis

Many people with arthritis report that the hydrogen peroxide bath has helped them greatly.

Organ Health


Some viruses are much more susceptible to ozone's action than others.  It has been found that lipid-enveloped viruses such as HBV and HCV are among the most sensitive.  While many doctors are reporting good success in treating Hepatitis with ozone, there have been limited studies performed.

In a small trial of 8 patients in which post treatment follow-up information was available, viral loads by Polymerase Chain Reaction, taken at the onset of ozone therapy, then repeated following completion of the therapy, were compared.  An average viral load reduction of 99.96% was achieved.  At the onset of treatment 7 of the 8 patients also had elevated liver enzyme levels – SGOT (AST) and SGPT (ALT).  Following ozone therapy these measures fell into the normal range.  This pilot trial, without a blind control group and conducted in an offshore setting, must be viewed as anecdotal although fully consistent with the experience of many.


Giardiasis Infection

Cuban doctors are using capsules filled with ozonated oil to treat gastroduodenal ulcers, gastritis, giardia and peptic ulcers.

In 50 cases of giardiasis which did not respond to conventional treatment, ozonated water was administered.  Each patient drank four glasses of ozonated water per day for ten days, followed by a 7-day period without treatment.  This cycle was then repeated a second time.  46% experienced a remission during the first cycle of treatment while an additional 48% became asymptomatic by the end of the second cycle.  There were no adverse side-effects reported. [Revista CENIC Ciencias Biologicas, pp. 61-4]


Herpes Simplex Type II

Dr. H. Konrad of Brazil published his results in treating genital herpes.  Out of 20 patients, all but 3 cleared and stayed in remission after ozone injections during the 2.5 year follow-up period.




Food grade hydrogen peroxide (36%) can be applied directly to the wart with a Q-tip, while being very careful not to contact normal skin.  Continue applying twice per day until the wart becomes white and the surrounding skin becomes somewhat white.  After a few days to two or three weeks, depending on location, it will start to blacken.  Continue applying until wart falls off.  Any skin damage to normal skin is temporary.  Hydrogen peroxide is dangerous around children, who may consume it or get it in their eyes.

Adult Acne

Ozonated olive oil used topically has a reputation for fighting acne.

Adolescent Acne

Ozonated olive oil used topically has a reputation for fighting acne.

Premature Hair Graying

There have been testimonies regarding partial restoration of hair color during the long-term use of hydrogen peroxide baths.  Head hair color may move slightly away from white toward its earlier color.  Men's chest hairs may recover their natural color to a greater degree than head hair.

Tumors, Malignant

Non-Hodgkin's Lymphoma

Ozone assists in reversing opportunist malignancies such as non-Hogkins lymphoma (especially if pulmonary) and lymphadenopathy-associated virii.

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