Definition of Pathway:

A sequence of chemical reactions leading from one compound to another.

Also: Biochemical Pathway, Biochemical Pathways, Chemical Pathway, Chemical Pathways, Pathways

Topics Related to Pathway

Acupuncture a treatment
“...A major part of the theory is that health is achieved through balancing yin and yang, and that disease is caused by an imbalance leading to a blockage in the flow of Qi (vital energy) along pathways known as meridians...”


...recommendation Kava
“...Although preliminary, due to the small sample size, a trial suggests that kava extract (280mg standardized extract per day) may target the baroreceptor pathway and improve Baroreflex control of heart rate (BRC) in patients with generalized anxiety...”
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More topics Related to Pathway

Biotin a treatment
“...Biotin plays an important role in some drug-detoxifying pathways.  It is an important enzyme cofactor...”

Bromelain a treatment
“...Here it is thought to work on both the fibrin and kinin pathways to decrease active inflammation, as well as prevent the blockage of other anti-inflammatory agents from entering the site of infection...”

Calcium-D-Glucarate a treatment
“...It assists and strengthens glucuronidation, the important Phase 2 detoxification pathway.  This reduces serum estrogen levels and assists in the detoxification and excretion of xenobiotics, lipid-soluble toxins, and steroid hormones...”

Cancer, General

...recommendation Vitamin D
“...More recent research suggests this is a causal relationship that acts through the body's vitamin D metabolic pathways.  For instance, some evidence points to a prostate, breast and colon cancer belt in the United States, which lies in northern latitudes under more cloud cover than other regions during the...”

Chemical Avoidance a treatment
“Avoiding the chemicals which trigger symptoms or increase disease risk reduces the burden on the body's detoxification pathways and tissues...”

Chronic Inflammation

...recommendation Bioflavonoids
“...However, several inflammation-promoting pathways are known to be inhibited by quercetin...”

Chronic Lymphocytic Leukemia (CLL)

...the condition
“...This distinguishes whether the lymphocytes that accumulate are derived from a malignant transformation of a lymphocyte in the B cell developmental pathway or the T cell developmental pathway...”

CLA (Conjugated Linoleic Acid) a treatment
“...In vitro studies have shown that the milk phospholipid, sphingomyelin, affects three different major antiproliferative pathways which influence oncogenesis...”


...relationship to Stress
“In a study of 34 women with chronic constipation, investigators led by Dr. Anton Emmanuel and colleagues at St. Mark's Hospital in Middlesex linked emotional distress with changes in the nerve pathway that helps control gut function...”

Degenerative Disc Disease (DDD)

...the condition
“...However, there are at least a dozen other types of surgical treatment available, involving procedures such as (from least to most invasive) ... enlarging or reconstructing the spinal canal (nerve pathway) to make more room for the spinal cord...”


...recommendation L-Phenylalanine
“Phenylalanine can affect depression via three separate pathways...”
...recommendation DHEA
“...It might modulate the serotonin-signaling pathway.  In addition, DHEA is the precursor for estrogen and testosterone, which also enhance mood...”

DIM / I3C a treatment
“...Some have suggested that DIM may also positively affect cellular signaling pathways, and thus regulate tumor promotion and progression...”

Effects of a Low Carbohydrate Diet

...the condition
“...But when your body runs out of carb fuel to burn, your body's only choice is to burn fat inefficiently using a pathway that produces toxic byproducts like acetone and other ketones...”

Environmental Illness / MCS

...the condition
“...The main mechanism for chemical sensitivity seems to be the failure of the body's enzyme detoxification pathways to adequately clear chemical compounds...”
...recommendation Liver Detoxification Phase II Support
“Reducing the body burden of chemicals can be enhanced by maximizing Phase II liver detoxification pathways with selected nutrients.”

Female Hair Loss

...relationship to Yeast / Candida Infection
“...The exact mechanism is unclear because there are so many possible pathways.  The three most likely pathways are thyroid dysfunction, allergies and enzyme suppression.”

Hearing Loss

...the condition
“...Sensorineural hearing loss refers to damage to the pathway for sound impulses from the hair cells of the inner ear to the auditory nerve and the brain...”
...relationship to Multiple Sclerosis
“Multiple sclerosis that affects auditory nerve pathways in the brain can cause sensorineural hearing loss.”

Hormone Imbalance

...the condition
“...Although men's and women's bodies share the same biochemical pathways for sex hormones, the specific hormones differ...”


...the condition
“...It is important to recognize that jaundice itself is not a disease, but rather a symptom of an underlying pathological process that occurs at some point along the normal physiological pathway of the metabolism of bilirubin...”

Krebs Cycle

...related topic
“The final chemical pathway in the conversion of nutrients to energy.”

Liver Detoxification / Support Requirement

...recommendation Coffee Enema
“...Coffee contains some alkaloids that also stimulate the production of glutathione-S-transferase, an enzyme used by the liver to make the detox pathways run.  It is pivotal in the formation of more glutathione, one of the main conjugation chemicals, enabling toxins to be eliminated via bile into the small intestine...”

Liver Detoxification Phase II Support a treatment
“...Phase II Detoxification This is called the conjugation pathway, whereby the liver cells add another substance (eg...”
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More topics Related to Pathway

L-Phenylalanine a treatment
“...L-phenylalanine can also be converted (through a separate pathway) to phenylethylamine, a substance that occurs naturally in the brain and appears to elevate mood...”

Magnesium a treatment
“...Magnesium Chelate (Amino Acid): A chemically reacted magnesium ion, bound to 1 or more amino acids, thus allowing the magnesium to enter through the intestinal wall via the amino acid pathway rather than active magnesium diffusion...”

Male Hair Loss

...relationship to Yeast / Candida Infection
“...The exact mechanism is unclear because there are so many possible pathways.  The three most likely pathways are thyroid dysfunction, allergies and enzyme suppression.”

Manganese a treatment
“...This allows the manganese to be absorbed via the amino acid pathway, rather than the active transport method for manganese...”

Meniere's Disease

...recommendation Antihistamines
“...Antihistamines are believed to suppress vertigo symptoms by blocking certain chemical pathways in the brain...”

Methionine a treatment
“...Methionine is one of only two amino acids that contains a sulfur group, important for methionine's role in the pathway of glutathione "charging"...”

Natural Progesterone a treatment
“...Most importantly, progestins lack the intrinsic physiological benefits of progesterone, thus they cannot function in the major biosynthetic pathways as progesterone does and they disrupt many fundamental processes in the body...”

Non-Aerobic Exercise / Weight Training a treatment
“...Circuit training's continuous cardiovascular requirements flushes toxins out from the tissues with the forcing of blood through the tubal pathways of the cardiovascular system...”

Periodontal Disease - Gingivitis

...relationship to Coronary Disease / Heart Attack
“...It can also lead to an increase in inflammation across the body; overactivity of inflammatory pathways is a strong risk factor for the development of atherosclerotic heart disease and heart attack.”

Poor Circulation

...recommendation Surgery
“...In a bypass operation, the surgeon grafts a segment taken from one of the patient's veins (or sometimes an artificial vessel) onto the clogged artery, giving blood a pathway around the blockage...”

Progesterone Low or Estrogen Dominance

...the condition
“...There are three types of natural estrogen, and multiple degradation pathways and metabolites...”

Pygeum a treatment
“...Additionally, pygeum extracts antagonize the production of metabolites in the 5-Lipoxygenase pathway (pathway in the arachidonic acid inflammation pathway)...”

Selegiline a treatment
“...Selegiline blocks the enzyme monoamine oxidase type B, which forms one of the metabolic pathways for dopamine in the brain...”

Shiitake Mushrooms a treatment
“...Lentinan activates the alternative complement pathway, stimulating the macrophages, thus inhibiting tumor growth...”

Susceptibility To Hangovers

...relationship to Liver Detoxification / Support Requirement
“...If the liver's detoxification pathways are impaired, aldehydes can, instead of being converted to the next intermediate product, build up to harmful levels and cause damage since they are often more toxic than the original...”

Susceptibility To Miscarriages

...the condition
“...INHERITED THROMBOPHILIAS The Inherited Thrombophilias comprise a group of genetic disorders of the blood clotting pathways, leading to abnormal blood clot formation...”

Syndrome X / Metabolic Syndrome

...recommendation Alpha Lipoic Acid
“...This process may occur via an insulin signaling pathway.  ALA also helps to prevent free radical cellular damage caused by elevated insulin levels.”

Testicular Cancer

...the condition
“...It can, however, disrupt the nerve pathways that control ejaculation, causing infertility...”

Thymic Factors a treatment
“...Vitamins and minerals serve as cofactors and catalysts in the enzymatic pathways that regulate our metabolism...”

Torn, weak, or Stretched Ligaments or Tendons

...the condition
“...Aspirin and other nonsteroidal anti-inflammatories (NSAIDs) can knock out or suppress the healing response by interfering with the prostaglandin growth factor pathways.  These drugs are frequently prescribed because they are thought to be safe and a conservative treatment modality...”

Vitamin B12 Requirement

...our question about Your urine MMA level
“...UMMA reflects cobalamin (Vitamin B12) activity at the tissue/cellular level since MMA levels are directly related to a B12-dependent metabolic pathway.  The conversion of MMA to succinic acid requires vitamin B12...”

Vitamin CoQ10 Need

...the condition
“...The resulting lowering of blood CoQ10 level is due to the partially shared biosynthetic pathway of CoQ10 and cholesterol...”
...our question about Cholesterol-lowering drug use
“...The resulting lowering of blood CoQ10 level is due to the partially shared biosynthetic pathway of CoQ10 and cholesterol.”

Vitex / Chasteberry a treatment
“...Vitex instead works through another important chemical pathway, the hypothalamus-pituitary axis, to balance female hormones...”
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