CLA (Conjugated Linoleic Acid)

CLA (Conjugated Linoleic Acid): Overview

Conjugated Linoleic Acid (CLA) is a potent antioxidant, immune stimulant, and anticancer agent in all species of animals tested.  It has also been found to 'repartition' their bodies, decreasing fat and increasing lean body mass.  At least one human study confirms these results, with other studies underway.

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CLA is a natural fatty acid found in beef, lamb, turkey and cheese.  Most Americans consume only 1gm of conjugated linoleic acid per day.  Whole milk usually contains 2mg per gram of fat but can be increased by feeding cows corn oil.


Preliminary studies in rat models showed that Conjugated Linoleic Acid has a powerful anticarcinogenic effect against mammary tumors.  CLA may have a direct effect by reducing the cancer risk of the target organ.  It is noted that, unlike CLA, most anticarcinogenic substances come from plant sources.

Cow's Milk – CLA appears to have an antiproliferative effect on human malignancy.  In vitro studies have shown that the milk phospholipid, sphingomyelin, affects three different major antiproliferative pathways which influence oncogenesis.  These pathways are inhibition of cell growth, induction of differentiation, and apoptosis.

One-third of all milk triglycerides contain one molecule of butyric acid, which is a potent inhibitor of proliferation and inducer of differentiation and apoptosis in a wide range of neoplastic lines.  An animal study suggests that dietary butyrate may also inhibit mammary tumorigenesis, as well as being an important colon cancer protective agent.


Dose: 1 to 3gm per day is a normal dose for healthy people.  A 70kg individual (154 pounds) would need to consume 3.5gm of CLA daily to receive benefit.

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CLA (Conjugated Linoleic Acid):

CLA (Conjugated Linoleic Acid) can help with the following:


Not recommended for


Problems Caused By Being Overweight

In animals, CLA helped repartition their body weight, decreasing fat and increasing lean body mass.  One human study confirms this.

Tumors, Malignant

Breast Cancer

For breast cancer prevention and treatment, it is suggested that 6 to 10 750mg capsules of CLA be taken daily.  When taking CLA, the breast cancer patient also must take soy.

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May be useful: may help with
May be useful:
may help with
Moderately useful: often helps with
Moderately useful:
often helps with
Should be avoided: is NOT recommended for
Should be avoided:
is NOT recommended for
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