Your Urine MMA Level

What Causes Elevated Urine MMA Levels?

Elevated urine MMA levels can have various causes, just like most other symptoms.  Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

Diagnose your symptoms now!
  • identify any nutritional deficiencies
  • have a doctor review your case (optional)
  • learn what you should be doing right now

Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms.  In order to diagnose elevated urine MMA levels, we could:

  • Research the topic
  • Find a doctor with the time
  • Use a diagnostic computer system.
The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "elevated urine MMA levels" as a symptom.  For example, vitamin B12 need.

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
copper supplementation
specific muscle weakness
long-term vegetarian/vegan diet
some vitamin B12 supplementation
diarrhea for 1-3 months
raw food diet
frequent confusion/disorientation
macrocytic red cells
having had a small bowel resection
broad-spectrum antibiotic use
history of B12 deficiency
frequent episodes of diarrhea
... and more than 10 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of elevated urine MMA levels.

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate having had recent lab tests, The Analyst™ will ask further questions including this one:
Urine MMA. Normal levels are below 3.8ug of MMA per mg of creatinine (below 3.6umol MMA per mmol of creatinine); Elevated levels are anything above this.
Possible responses:
→ Don't know
→ Normal
→ Elevated
Based on your response to this question, which may indicate either normal urine MMA levels or elevated urine MMA levels, The Analyst™ will consider possibilities such as Vitamin B12 Requirement.  The UMMA test is a functional assay.  UMMA reflects cobalamin (Vitamin B12) activity at the tissue/cellular level since MMA levels are directly related to a B12-dependent metabolic pathway.  The conversion of MMA to succinic acid requires vitamin B12.  The metabolic pathway is: MMA → (coenzyme B12 ) → succinic acid.

Vitamin B12 deficiency impedes this pathway and causes MMA levels to increase.  Thus, as water builds up behind a dam, high UMMA levels indicate a vitamin B12 deficiency.
Concerned or curious about your health?  Try The Analyst™
Symptom Entry
Symptom Entry
Full Explanations
Optional Doctor Review
Review (optional)
We use cookies for traffic analysis, advertising, and to provide the best user experience