Unexplained Nausea

What Causes Unexplained Nausea?

Unexplained nausea can have various causes, ranging in severity from 'minor' to 'generally fatal'.  Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

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Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms.  In order to diagnose unexplained nausea, we could:

  • Research the topic
  • Find a doctor with the time
  • Use a diagnostic computer system.
The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "unexplained nausea" as a symptom.  Here are eight of many possibilities (more below):
  • High Histamine
  • Cirrhosis Of The Liver
  • Hepatitis
  • Gallbladder Disease
  • Zinc Toxicity
  • Magnesium Toxicity
  • Candida / Yeast
  • Gastritis

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
meals worsen top-left abdomen pain
suspected vaginal yeast infection
allergy to chemicals
stabbing epigastric pain after meals
epigastric pressure after meals
loss of appetite
frequent aspirin use
regular episodes of diarrhea
frequent bowel movement changes
major unexplained weight loss
significant epigastric pain
edema of the abdomen
... and more than 130 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of unexplained nausea:
Cause Probability Status
Hepatitis 97% Confirm
Zinc Toxicity 28% Unlikely
Cirrhosis Of The Liver 22% Unlikely
Gastritis 1% Ruled out
Magnesium Toxicity 0% Ruled out
High Histamine 0% Ruled out
Candida / Yeast 0% Ruled out
Gallbladder Disease 0% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

In the Gastrointestinal Symptoms section of the questionnaire, The Analyst™ will ask the following question about unexplained nausea:
Approximately how often do you suffer from unexplained nausea? Do not include nausea that has an obvious cause, for example pregnancy, hunger or motion sickness.
Possible responses:
→ Don't know
→ Never / very rarely
→ Occasionally - a few times per year
→ Regularly - a few times per month
→ Often - several times per week
Based on your response to this question, which may indicate no unexplained nausea, occasional unexplained nausea, regular unexplained nausea or frequent unexplained nausea, The Analyst™ will consider possibilities such as:
Congestive Heart Failure

Accumulation of fluid (due to congestive heart failure) in the liver and intestines may cause nausea, abdominal pain, and decreased appetite.


Water is essential to the biochemical reactions within our bodies, including those related to the stomach.  When dehydration limits the proper functioning of the stomach, it can cause nausea.  The reverse is also true, however: A nauseous person will often become dehydrated because drinking fluids can worsen nausea or induce vomiting.

Fluoride Toxicity

Nausea is an early sign of fluoride toxicity.


Acute gastroenteritis is a common cause of acute care-seeking and is second only to the common cold as a cause of lost work time.  Bacterial, viral, and parasitic pathogens cause this illness which is characterized by diarrhea and/or vomiting.  Vomiting is especially common with infections caused by rotaviruses, enteric adenovirus, Norwalk agent, and calicivirus.


In more severe cases there may be loss of appetite, nausea, vomiting, constipation, confusion or impaired thinking and memory, and increased thirst and urination.

IBS (Irritable Bowel Syndrome)

IBS can lead to nausea in various ways:

  • IBS commonly causes indigestion and subsequent acid reflux, which can cause nausea
  • Feeling stressed or anxious as a result of IBS can cause nausea
  • The abdominal pain often present in IBS may result in nausea
  • IBS can cause constipation, which can put stress on the liver, and liver problems can cause nausea

Nausea, vomiting, and diarrhea may occur.

Zinc Toxicity

Symptoms of zinc toxicity include nausea, vomiting and fever.

Concerned or curious about your health?  Try The Analyst™
Symptom Entry
Symptom Entry
Full Explanations
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