Stomach Ulcers

What Causes Stomach Ulcers?

In order to deal properly with stomach ulcers we need to understand and — if possible — remove the underlying causes and risk factors.  We need to ask: "What else is going on inside the body that might allow stomach ulcers to develop?"

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Accurate diagnosis of the factors behind stomach ulcers consists of three steps:

Step 1: List the Possible Causative Factors

Identify all disease conditions, lifestyle choices and environmental risk factors that can lead to stomach ulcers.  Here are seven possibilities:
  • Gastritis
  • Atrophic Gastritis
  • Hyperparathyroidism
  • Stress
  • Cigarette Smoke Damage
  • Helicobacter Pylori Infection
  • Heartburn

Step 2: Build a Symptom Checklist

Identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
regular unexplained vomiting
frequent nightmares
magnesium-based antacid use
history of gastritis
calcium-based antacid use
moderate meal-induced pain
chronic nausea
reduced sense of smell
moderate unexplained weight loss
a high-stress lifestyle
high refined sugar consumption
heart racing/palpitations
... and more than 100 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of stomach ulcers:
Cause Probability Status
Atrophic Gastritis 94% Confirm
Stress 24% Unlikely
Cigarette Smoke Damage 19% Unlikely
Helicobacter Pylori Infection 1% Ruled out
Hyperparathyroidism 1% Ruled out
Heartburn 0% Ruled out
Gastritis 0% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate digestive problems, The Analyst™ will ask further questions including this one:
Have you had Peptic Ulcers, also known as Stomach Ulcers or Gastric Ulcers?
Possible responses:
→ Never had one / don't know
→ Probably/minor episode now resolved
→ Major episode now resolved
→ Current minor problem
→ Current major problem
Based on your response to this question, which may indicate either history of stomach ulcers or stomach ulcers, The Analyst™ will consider possibilities such as:

Patients with hyperparathyroidism may be more likely to develop peptic ulcers, high blood pressure, and pancreatitis.

Cigarette Smoke Damage

Smoking is associated with the development, delayed healing and recurrence of peptic ulcers, as well as resistance to treatment.


Severe inflammation of the stomach lining (gastritis) can result in ulceration.

Heartburn / GERD / Acid Reflux

There is a relatively high prevalence of GERD amongst patients with duodenal or gastric ulcers.  Persistent dyspepsia/heartburn symptoms after eradication of H. pylori and ulcer resolution might suggest the treatment of GERD as a separate entity. [Am J Gastroenterol 2000;95: pp.101-5]


In general the duodenum isn't as well protected with mucus as is the stomach and is more prone to ulcers.  A deficiency of pancreatic juices to neutralize the acid chyme from the stomach, or stress causing sympathetic inhibition of enzyme secretion can lead to duodenal ulcer formation.

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