Histadelia (Histamine High)

Histamine can cause additional mucus production.

Histamine speeds up metabolism producing a tendency towards hyperactivity.

Those with elevated histamine (histadelics) tend to work compulsively.

Histadelics are often highly creative.

Histadelics often have long fingers and toes.

Histadelics often have long fingers and toes.

Histadelics are often prone to obsessions, compulsions, and addictions.

Histadelics are often chronically and suicidally depressed.

Some 15-20% of "schizophrenic" patients are in fact suffering from histadelia, which shares similar symptoms and can be misdiagnosed.

Methionine supplements lower blood levels of histamine by increasing histamine breakdown.

Nutritionists recommend a low-protein, high complex carbohydrate diet.  Histidine, which is more common in animal proteins, should be avoided as it can be converted into histamine.

Testing serum or hair copper levels is usually adequate for evaluating copper status when low levels of copper are suspected and hair contamination with copper can be ruled out.  When in doubt, it would be better to use more accurate tests such as the 24 hour urine copper or serum ceruloplasmin.

Under certain conditions, such as anticipated or actual pregnancy, a simple lab test for serum folate levels is advisable.  If the test results show low levels, supplementation should be considered to prevent potential birth defects.

Copper levels may be low to normal in patients with histadelia.  Copper is part of the enzyme histaminase, which is involved in the metabolism of histamine.

Histadelics should avoid supplemental folic acid as it can produce excess histamine.  In fact, anti-folate drugs may be required.  Folic acid increases depression in histadelic patients and a trial of folic acid could be used to distinguish between histapenics and histadelics.  In extreme cases, folic acid in food or in multivitamins is enough to produce the adverse effects.