Autoimmune Disease

Definition of Autoimmune Disease:

One of a large group of diseases in which the immune system turns against the body's own cells, tissues and organs, leading to chronic and often deadly conditions.  Examples include multiple sclerosis, rheumatoid arthritis, systemic lupus, Bright's disease and diabetes.

Also: Autoimmune, Autoimmunity

Topics Related to Autoimmune Disease

A Low IgA Level

...the condition
“...Some people are born with low or absent levels of IgA antibodies, which increases their chances of developing an autoimmune disease...”

A Low IgE level

...the condition
“...Also, high levels of IgE are found in people who have allergic reactions, asthma, atopic dermatitis, some types of cancer, and certain autoimmune diseases...”
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More topics Related to Autoimmune Disease

A Low Platelet Count

...the condition
“...ITP has two basic origins: an autoimmune attack against platelets (primary or autoimmune ITP) and a bone marrow disorder (secondary ITP)...”

Ankylosing Spondylitis

...the condition
“Ankylosing spondylitis is an autoimmune disease which affects collagen structures, specifically the joints between the vertebrae of the spine...”
...relationship to Bacterial Dysbiosis
“...In an autoimmune reaction to excessive amounts of Klebsiella, the immune system attacks the spine...”

Antibody

...related topic
“...Antibody activity normally fights infection but can be damaging in allergies and a group of diseases that are called autoimmune diseases...”

Astragalus Root

...as a treatment
“...As an immune system enhancer, astragalus root may also be a promising treatment for HIV and for autoimmune diseases such as lupus...”

Atrophic Gastritis

...relationship to Megaloblastic Anemia / Pernicious Anemia
“Gastric autoimmune disease has been classified into types A and B, based on the changes in different portions of the stomach...”

Autoimmune Tendency

...the condition
Autoimmune diseases result from the body's immune system mistaking the tissues its own body for foreign invaders, and attacking them...”
...recommendation Hydrochloric Acid (Trial)
“Clinicians report that 50% of patients with autoimmune disease are also hypochlorhydric (have low stomach acid)...”
...recommendation Gluten-free Diet
“Some doctors have found that a higher than normal percentage of patients with autoimmune disorders are allergic to gluten/gliadin and dairy products...”
...recommendation Therapeutic Fasting
“...He has an entire chapter in his book, Fasting and Eating for Health, dedicated to the subject of autoimmune disease...”
...recommendation Test for DHEA
“Some doctors report finding that a high percentage of patients with autoimmune disorders are also deficient in DHEA, and should be tested...”
...recommendation Test Copper Levels
“In cases of autoimmune disease, where therapy is often less than satisfactory, copper insufficiency should be investigated until additional studies confirm any link...”
...recommendation against Melatonin
“Melatonin enhances the immune system and therefore those with autoimmune diseases should use melatonin only in very low doses...”

Bacterial Dysbiosis

...the condition
“...Complications: Bacterial antigens may elicit dysfunctional immune responses which contribute to autoimmune diseases of the bowel and of connective tissue...”

Cancer, General

...our question about Vegetarian, vegan or raw-food diet
“There has long been suspicion that components of meat and dairy were absorbed intact through the human digestive tract, triggering autoimmune disorders such as rheumatoid arthritis and childhood diabetes as our bodies try to fight off these foreign substances...”

Cardiomyopathy

...the condition
“...Restrictive cardiomyopathy is usually due to a connective tissue disease, cancer, or an autoimmune condition...”

Chronic / Hidden Infection

...the condition
“...Alternatively, the bug may induce a so-called autoimmune response...”

Chronic Inflammation

...the condition
“...This is true regardless of whether the injury results from a cut, burn, bruise, infection, or even an autoimmune disease such as rheumatoid arthritis...”

Chronic Renal Insufficiency

...the condition
“...Some ways to help prevent or slow down the onset of chronic renal failure include ... reducing autoimmunity activity...”

Chronic Thyroiditis

...the condition
“...When Hashimoto's disease occurs with adrenal insufficiency and type 1 diabetes mellitus, the condition is called type 2 polyglandular autoimmune syndrome (PGA II)...”
...relationship to Gluten Sensitivity / Celiac Disease
“People with celiac disease are more likely to develop Autoimmune Thyroid Disease (ATD) than the general public, and the reverse is also true...”
...recommendation Gluten-free Diet
“Some doctors recommend the complete avoidance of gluten/gliadin and dairy products when this allergy is suspected in cases of thyroiditis or other autoimmune disease...”
...recommendation Hydrochloric Acid (Trial)
“Some doctors report that 50% of patients with autoimmune disease are also hypochlorhydric (have low stomach acid)...”
...recommendation DHEA
“Some doctors report finding that a high percentage of patients with autoimmune disorders, such as thyroiditis, are also deficient in DHEA, and should be tested...”
...recommendation Selenium
“Three months of supplementation with 200mcg selenium daily reduced thyroid peroxidase antibodies (TPOAb) but had no effect on Tg antibodies (TgAb) in a well-controlled study of 70 women with autoimmune thyroiditis...”

Cigarette Smoke Damage

...relationship to Chronic Thyroiditis
“...The association was most pronounced in autoimmune disorders (Graves' disease and autoimmune thyroiditis), although there was still a strong association for non-autoimmune thyroid disorders...”
...relationship to Hyperthyroidism
“...The association was most pronounced in autoimmune disorders (Graves' disease and autoimmune thyroiditis), although there was still a strong association for non-autoimmune thyroid disorders...”
...relationship to Buerger's Disease
“...Recent work suggests that Buerger's disease may be a reaction to tobacco of persons with a specific genetic type or an autoimmune disorder with immune cell sensitivity to some collagen types, which are constituents of blood vessels...”

Cirrhosis of the Liver

...the condition
“...Autoimmune hepatitis is caused by a problem with the immune system...”

Collagen Vascular Disease

...the condition
“Collagen vascular disease is a class of autoimmune disease that affects collagen...”

Cytomegalovirus (CMV) Infection

...relationship to Sjogren's Syndrome
“...researchers published their research findings in the journal Immunity that chronic cytomegalovirus (CMV) infection can lead to the development of Sjogren's syndrome, the second-most common autoimmune disease...”

Depression

...recommendation against Melatonin
“On the basis of theoretical ideas about how melatonin works, some authorities specifically recommend against using it for depression, schizophrenia, autoimmune diseases and other serious illnesses, and in pregnant or nursing women...”

Dermatitis Herpetiformis

...the condition
“...DH is related to celiac disease since both are autoimmune disorders caused by gluten intolerance, but they are separate diseases...”

Dermatomyositis

...the condition
“...Both are thought to be autoimmune diseases, in which the body's immune system attacks the muscles...”

DHEA

...as a treatment
“...In over 2,500 medical references regarding this substance, there are some excellent articles in the prevention of cancer, arteriosclerosis, autoimmune diseases such as lupus, chronic fatigue syndrome, Alzheimer's disease, hypercholesterolemia, depression and osteoporosis...”

Diabetes Insipidus

...the condition
“...Causes and Development: Causes of central DI include surgical removal of the hypothalamus, tumors of the hypothalamus or the pituitary gland, infection of the pituitary gland, autoimmune damage of the pituitary gland, and familial disease of the pituitary gland...”

Diabetes Type 1.5

...the condition
“...This sort of diabetes is sometimes called Slow Onset Type 1 or Latent Autoimmune Diabetes in Adults (LADA)...”

Diabetes Type II

...relationship to Autoimmune Tendency
“Type 2 diabetes is in the process of being redefined as an autoimmune disease rather than just a metabolic disorder...”

DMSO Topically

...as a treatment
“...use it for all sorts of inflammatory conditions, from people with rheumatoid arthritis to people with chronic low back inflammatory-type symptoms, silicon immune toxicity syndromes and any kind of autoimmune process...”

Encephalitis

...the condition
“... Damage to nerve cells in such cases is caused not by the viral infection, however, but most likely by an autoimmune reaction, in which the body's immune system attacks its own brain tissue...”

Enlarged Spleen

...the condition
“...hypertension); Sclerosing cholangitis; Wilson's disease; Biliary atresia; Cystic fibrosis; Hemolytic anemias Thalassemia; Hemoglobinopathies; Hemolytic anemia due to G6PD deficiency; Idiopathic autoimmune hemolytic anemia; Immune hemolytic anemia; Cancers Leukemia; Lymphoma; Hodgkin's disease; Other causes Sarcoidosis; Sickle cell splenic crisis; Banti's syndrome; Felty syndrome; Signs...”

Environmental Illness / MCS

...relationship to Autoimmune Tendency
“Reports of autoimmune markers in MCS patients, like most MCS data, are inconsistent...”

Fish Oils

...as a treatment
“...also suggest that fish oil may be helpful in Raynaud's phenomenon (a condition in which a person's hands and feet show abnormal sensitivity to cold temperatures), psoriasis, sickle-cell anemia, the autoimmune disease lupus, and a form of kidney disease called IgA nephropathy...”

Gastritis

...the condition
“...Laboratory Findings ... Intrinsic-factor antibodies occur in many cases of autoimmune chronic gastritis that result in pernicious anaemia...”

Glutamine

...as a treatment
“...Glutamine is a "brain food"; it helps build and maintain muscle; useful in weight loss and bodybuilding; used to treat arthritis, autoimmune diseases, fibrosis, intestinal disorders (such as Crohn's disease, irritable bowel disease, ulcerative colitis), lupus, connective tissue disease and tissue damage from radiation...”

Gluten Sensitivity / Celiac Disease

...the condition
“...Celiac disease is considered an autoimmune disorder because the body's own immune system causes the damage...”

Guillain-Barre Syndrome

...the condition
“...Some theories suggest an autoimmune mechanism, in which the patient's defense system of antibodies and white blood cells are triggered into damaging the nerve covering or insulation, leading to weakness and abnormal sensation...”

Hemolytic Anemia

...the condition
“...Autoimmune Hemolytic Anemia includes any of a large group of anemias involving autoantibodies against red cell antigens...”

Histamine Therapy

...as a treatment
“...administering small doses of histamine is meant to balance out the parts of the immune system that stimulates allergies or auto-immunity, and the parts of the immune system that keep the allergic or autoimmune reactions under control...”

Hives (Urticaria)

...the condition
“...hepatitis B virus, candida albicans, streptococcal bacteria), collagen vascular diseases, autoimmune diseases or other metabolic disorders, cancer, psychological, hypothyroidism, polycythemia vera, protoporphyria (even without excessive sun exposure)...”
...relationship to Autoimmune Tendency
“Some forms of chronic hives have an autoimmune origin which means, in about 30% of patients, that the immune system is producing antibodies against normal substances in the body and triggering the release of histamine by mast cells...”

Hot Applications (Thermotherapy)

...as a treatment
“...Therapeutic use of heat may help treat this chronic pain condition, characterized by musculoskeletal aches, Lupus is a chronic autoimmune disease that can cause joint pain and inflammation (arthritis)...”

Hyperthyroidism

...the condition
“...There is a genetic predisposition to autoimmune disorders and infections and stress play a part...”
...relationship to Autoimmune Tendency
“The leading cause of hyperthyroidism is Graves' disease, which is an autoimmune disorder...”
...recommendation Selenium
“...Barbara Gasnier reported the findings at the 83rd Annual Meeting of the Endocrine Society in Denver, Colorado that selenium supplementation may prevent progression of autoimmune thyroid disease, especially during the onset of the disease...”
...recommendation Test for DHEA
“Some doctors report finding that a high percentage of patients with autoimmune disorders, such as Graves' disease, are also deficient in DHEA, and should be tested...”
...recommendation Hydrochloric Acid (Trial)
“Some doctors report that 50% of patients with autoimmune disease are also hypochlorhydric...”
...recommendation Gluten-free Diet
“Some doctors recommend the complete avoidance of gluten/gliadin and dairy products when this allergy is suspected in cases of Graves' disease or other autoimmune disease...”

Hypothyroidism

...the condition
“...Caused in almost all cases by autoimmune disease, the result is that the immune system goes awry and begins gradually to destroy the thyroid gland...”
...relationship to Megaloblastic Anemia / Pernicious Anemia
“Pernicious anemia is associated with other autoimmune conditions such as Hashimoto's disease, a form of hypothyroidism...”

Immune System Imbalance (TH2 Dominance)

...the condition
“...The inability to respond adequately with a Th1 response can result in chronic infection and cancer; an overactive Th2 response can contribute to allergies, various syndromes and play a role in autoimmune disease...”

Immunotherapy

...as a treatment
“...Immune suppression dampens an abnormal immune response in autoimmune diseases or reduces a normal immune response to prevent rejection of transplanted organs or cells...”

Increased Intestinal Permeability / Leaky Gut

...the condition
“...This is how autoimmune diseases, like MS or arthritis "work"...”
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More topics Related to Autoimmune Disease

Iritis

...related topic
“...Rheumatoid Iritis: An autoimmune (rheumatoid factor) inflammation of the iris...”

Juvenile Rheumatoid Arthritis

...recommendation Bacteria / Pathogen Testing by PCR
“An Autoimmune/Arthritis Disease Panel (Blood) can test for the presence of Mycoplasma fermentans, Mycoplasma pneumoniae and Epstein-Barr Virus (EBV)...”

LDN - Low Dose Naltrexone

...as a treatment
“...FDA-approved naltrexone, in a low dose (only 3mg), can boost the immune system, helping those with HIV/AIDS, cancer, and autoimmune diseases...”

Liver Function Test Requirement

...the condition
“...The presence of these antibodies can indicate primary biliary cirrhosis, chronic active hepatitis, and certain other autoimmune disorders...”

Lupus, SLE (Systemic Lupus Erythematosus)

...the condition
“Systemic Lupus Erythematosus (SLE) is a chronic, potentially fatal autoimmune disease characterized by exacerbations and remissions with many clinical manifestations, and may mimic infectious mononucleosis, lymphoma or other systemic disease...”
...relationship to Chronic Thyroiditis
“Approximately 10% of lupus patients have thyroid antibodies, and autoimmune thyroiditis occasionally coexists with SLE...”
...recommendation Hydrochloric Acid (Trial)
“Stomach acid levels are generally lower in patients with autoimmune diseases...”
...recommendation MSM (Methyl Sulfonyl Methane)
“"MSM has been shown to be clinically helpful in lupus and may be beneficial in other autoimmune disorders as well...”
...recommendation Test for DHEA
“DHEA is almost always low in patients with autoimmune conditions such as SLE...”

Megaloblastic Anemia / Pernicious Anemia

...the condition
“...Diagnosis and Tests: Between 50 and 75% of patients with pernicious anemia have antibodies to IF, and 93% have antibodies to parietal cells which means this is another autoimmune disorder...”
...relationship to Chronic Thyroiditis
“Pernicious anemia is more common in people who have other autoimmune diseases such as thyroiditis...”

Melatonin

...as a treatment
“...On the basis of theoretical ideas about how melatonin works, some authorities specifically recommend against using it for depression, schizophrenia, autoimmune diseases and other serious illnesses, or by pregnant or nursing women...”

Mercury Toxicity (Amalgam Illness)

...relationship to Multiple Sclerosis
“...Mercury has long been linked to autoimmune diseases such as MS because of its affinity to attach to collagen tissue, which is the most common protein in the body...”

Monocytes Elevated

...the condition
“...Causes and Development: An increased number of monocytes in the blood (monocytosis) occurs in response to chronic infections, in autoimmune disorders, in blood disorders, and in cancers...”

Motherhood Issues

...recommendation against Melatonin
“On the basis of theoretical ideas about how melatonin works, some authorities specifically recommend against using it for depression, schizophrenia, autoimmune diseases and other serious illnesses, and in pregnant or nursing women...”

Multiple Sclerosis

...the condition
“...MS is not a genetically transmitted disease; it may be an autoimmune disease, with some part of the body attacking itself...”
...recommendation Calcium-2AEP
“Calcium EAP protects the myelin sheath from damage by an autoimmune response...”

Muscle Pains (Myalgia)

...the condition
“...However, muscle pain can accompany many other conditions such as infectious disease, autoimmune disease, parasitosis and other problems...”

Myasthenia Gravis

...the condition
“Myasthenia gravis is a chronic autoimmune neuromuscular disease characterized by fatigue and varying degrees of episodic weakness of the voluntary muscles...”
...relationship to Autoimmune Tendency
“About 5-10% of patients with myasthenia gravis also have other autoimmune diseases...”
...recommendation Gluten-free Diet
Autoimmune diseases in general have a higher prevalence of gluten intolerance...”
...recommendation Hydrochloric Acid (Trial)
“Stomach acid levels are generally lower in patients with autoimmune diseases...”
...recommendation Test for DHEA
“DHEA is almost always low in patients with autoimmune conditions such as myasthenia gravis...”
...recommendation Essential Fatty Acids
“Essential fatty acids have been shown to suppress autoimmune attacks in general and to help protect myelin sheaths...”

Neem

...as a treatment
“...Arthritis: The different types of arthritis ailments can be attributed to autoimmune disorders, infections, the result of wear and tear on the joints or inflammation...”

Neutropenia

...the condition
“...This may be related to having an autoimmune condition, such as...”
...relationship to Autoimmune Tendency
Autoimmune disease can cause chronic neutropenia...”

Oral Lichen Planus

...the condition
“Oral lichen planus is an autoimmune inflammatory condition affecting the mucous membranes of the mouth...”

Osteonecrosis

...the condition
“...Rheumatoid Arthritis is an inflammatory autoimmune disease in which the body's natural defenses against foreign agents (antibodies & lymphocytes) attack healthy joints...”

Panic Attacks

...the condition
“...Occasionally an under-active thyroid condition called Hashimoto's autoimmune thyroiditis, known as HAIT or, simply, thyroiditis has been associated with a range of anxiety symptoms including panic attack...”
...relationship to Chronic Thyroiditis
“Hashimoto's autoimmune thyroiditis has been associated with a range of anxiety symptoms including panic attack...”
...recommendation Test Thyroid Function
“Hashimoto's autoimmune thyroiditis has been associated with a range of anxiety symptoms including panic attack...”

Pleurisy

...the condition
“...The underlying medical conditions that can cause pleurisy are numerous and include ... Autoimmune conditions such as lupus, rheumatoid arthritis and autoimmune hepatitis...”

Pregnancy-Related Issues

...recommendation against Melatonin
“On the basis of theoretical ideas about how melatonin works, some authorities specifically recommend against using it for depression, schizophrenia, autoimmune diseases and other serious illnesses, and in pregnant or nursing women...”

Psoriasis

...the condition
“...It may be aggravated by injury or irritation (cuts, burns, rash, insect bites), and it may be severe in immunosuppressed people (such as with chemotherapy for cancer, or with AIDS) or those who have autoimmune disorders such as rheumatoid arthritis...”

Rashes

...the condition
“...Stress, hormonal changes, genetic predisposition, and autoimmune problems are among the factors thought to be associated with some skin rashes...”

Retinitis Pigmentosa

...relationship to Lupus, SLE (Systemic Lupus Erythematosus)
“Systemic Lupus Erythematosus (SLE) is an autoimmune disease sometimes misdiagnosed as retinitis pigmentosa...”
...relationship to Sjogren's Syndrome
“Sjogren's is an autoimmune disease sometimes misdiagnosed as retinitis pigmentosa...”

Rheumatoid Arthritis

...related topic
“A long-term, destructive connective tissue disease that results from the body rejecting its own tissue cells (autoimmune reaction)...”
...our question about Eye moistness or dryness
“"Dry eye" is a symptom of certain autoimmune diseases like rheumatoid arthritis and Sjogren's syndrome...”
...recommendation Therapeutic Fasting
“...Fasting can cause regression of some autoimmune and inflammatory disorders, such as rheumatoid arthritis...”
...recommendation Bacteria / Pathogen Testing by PCR
“An Autoimmune/Arthritis Disease Panel (Blood) can test for the presence of Mycoplasma fermentans, Mycoplasma pneumoniae and Epstein Barr Virus (EBV)...”

Scleroderma

...the condition
“Scleroderma is a rare, chronic autoimmune disease that causes skin to thicken and tighten...”
...related topic
“An autoimmune disease of the connective tissue, characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body...”

Sickle Cell Trait / Disease

...the condition
“...If the anemia is the result of autoimmunity, managing it may include avoiding suspect medications, treating related infections and taking immunosuppressive drugs, such as corticosteroids...”

Sjogren's Syndrome

...the condition
“Sjogren's (Sjögren's, pronounced SHOW-grins) syndrome is an autoimmune disease in which the immune system targets moisture-producing glands and causes dryness in the mouth and eyes...”
...our question about Eye moistness or dryness
“"Dry eye" is a symptom of certain autoimmune diseases like rheumatoid arthritis and Sjogren's syndrome, in which the body's immune system mistakenly attacks the tear ducts and saliva glands...”

Stiff Man Syndrome

...the condition
“...The disorder's cause is unknown, although evidence is pointing increasingly to the fact that it is an autoimmune disorder...”

Susceptibility To Miscarriages

...the condition
“...However, some have underlying autoimmune tendencies and should be appropriately evaluated...”
...relationship to Lupus, SLE (Systemic Lupus Erythematosus)
“...Although most women who suffer recurrent miscarriages do not have clinical signs of SLE, many exhibit autoimmune phenomena which is similar to that seen in SLE patients...”

Tendency Toward Postpartum Depression

...recommendation against Melatonin
“On the basis of theoretical ideas about how melatonin works, some authorities specifically recommend against using it for depression, schizophrenia, autoimmune diseases and other serious illnesses, and in pregnant or nursing women...”

Test Immune System Function

...as a treatment
“...Dysregulation of the immune system may result in autoimmune diseases, allergies, infections or tumors...”

Therapeutic Fasting

...as a treatment
“...Conditions responding to fasting include: Headaches, hypoglycemia, diabetes, autoimmune diseases, cardiovascular disease, hypertension, acne and eczema, tinnitus, vertigo, fibromyalgia, glaucoma, cervical dysplasia, chronic neck and back pain, polymyalgia rheumatica, and many...”

Thymic Factors

...as a treatment
“...Lower thymic hormone levels in the blood are associated with depressed immunity, and are typical of the elderly, individuals with chronic infections, autoimmune disorders, cancer and AIDS patients...”

Thyroiditis

...related topic
“Inflammation of the thyroid; there are several forms of thyroiditis, including chronic or Hashimoto's thyroiditis (also called autoimmune or chronic lymphocytic thyroiditis), subacute thyroiditis, and painless or postpartum thyroiditis...”

Ulcerative Colitis

...recommendation Hydrocortisone
“Ulcerative colitis is both an autoimmune disorder and sensitive to stress...”
...recommendation Test for DHEA
“DHEA can be a factor in autoimmune problems, which some consider ulcerative colitis to be...”

Ultraviolet Light Therapy

...as a treatment
“...Inflammatory disease Acne; Allergic gastritis; Arthritis; Autoimmune thyroiditis; Bursitis; Boils; Mastitis; Osteomyelitis; Pancreatitis; Periodontitis; Peritonitis; Rhinitis, sinusitis; Septicemia; Diseases due to inadequate peripheral circulation...”

Urticaria

...related topic
“...It can be caused by metabolic diseases, medications, infectious diseases, autoimmune disease, or physical sensitivity...”

Vitiligo

...the condition
“...The body may destroy its own tissue (an autoimmune reaction)...”

Vulvodynia / Vestibulitis

...relationship to Yeast / Candida Infection
“...[Autoimmunity as a factor in recurrent vaginal candidiasis and the minor vestibular gland syndrome...”

Weakened Immune System

...the condition
“...Such conditions include, but are not limited to, multiple sclerosis, fibromyalgia, autoimmune disorders in general, primary chronic polyarthritis, chronic candidiasis, cancer, neurodermatitis, ulcerative colitis, Crohn's disease, food and other allergies, Chronic Fatigue Syndrome...”
...relationship to Non-Hodgkin's Lymphoma
“Non-Hodgkin's lymphoma is more common among people with inherited immune deficiencies, autoimmune diseases, or HIV/AIDS, and among people taking immunosuppressant drugs following organ transplants...”

Zinc Toxicity

...relationship to Autoimmune Tendency
“Prolonged large doses of zinc may, by lowering manganese levels, increase susceptibility to autoimmune reactions...”
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