What Causes Unexplained Sadness?

Unexplained sadness can have various causes, ranging in severity from 'worrying' to 'very serious'. Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

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Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms. In order to diagnose unexplained sadness, we could:

Research the topic
Find a doctor with the time
Use a diagnostic computer system.

The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "unexplained sadness" as a symptom. Here are four possibilities:

Depression
Bipolar Disorder
Hypothyroidism
PMS D

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:

premenstrual abdominal bloating

occasional racing thoughts

very low free T4

elevated TSH

missing outer third of eyebrows

history of frequent dieting

depression with some anxiety

yellow/yellowish fingernails

T3-only thyroid hormone use

much reduced sense of smell

regular sleep paralysis

frequent colds/flus

... and more than 60 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of unexplained sadness:

Cause	Probability	Status
Depression	99%	Confirm
PMS D	29%	Unlikely
Bipolar Disorder	1%	Ruled out
Hypothyroidism	0%	Ruled out

* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

In the Emotional Symptoms section of the questionnaire, The Analyst™ will ask the following question about unexplained crying/sadness/tears:

Do you cry or become teary/sad for no reason?

Possible responses:

→ No / don't know
→ Very rarely - no more than once a year
→ Occasionally - a few times a year
→ Regularly - at least once a month
→ Often - several times a week

Based on your response to this question, which may indicate unexplained sadness/crying, regular unexplained sadness/crying or frequent unexplained sadness/crying, The Analyst™ will consider possibilities such as:

Bipolar Disorder, Manic-Depressive

Depression

Hypothyroidism

Premenstrual Syndrome PMS D (Depression)

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