Unexplained Sore, Tender Or Aching Muscles

What Causes Tender Muscles?

Tender muscles can have various causes, ranging in severity from 'minor' to 'generally fatal'.  Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

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Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms.  In order to diagnose tender muscles, we could:

  • Research the topic
  • Find a doctor with the time
  • Use a diagnostic computer system.
The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "tender muscles" as a symptom.  Here are eight of many possibilities (more below):
  • Vitamin D Need
  • Multiple Chemical Sensitivity
  • Silicone Disease
  • Lupus (SLE)
  • Valley Fever (Coccidioidomycosis)
  • Pulmonary Fibrosis
  • Guillain-Barre Syndrome
  • High Histamine

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
frequent confusion/disorientation
unsound sleep
frequent infections
loss of appetite
specific muscle weakness
swollen cervical nodes
heaviness of the legs
history of non-vaginal candidiasis
multiple painful inguinal nodes
frequent sore throats
poor tolerance of heat
being highly motivated
... and more than 90 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of tender muscles:
Cause Probability Status
Valley Fever (Coccidioidomycosis) 96% Confirm
Guillain-Barre Syndrome 28% Unlikely
Silicone Disease 13% Unlikely
High Histamine 3% Ruled out
Lupus (SLE) 3% Ruled out
Vitamin D Need 3% Ruled out
Multiple Chemical Sensitivity 1% Ruled out
Pulmonary Fibrosis 1% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate having muscle problems / disease, The Analyst™ will ask further questions including this one:
Do your muscles ache, or feel generally sore or tender to the touch for no obvious reason? Do not include sore muscles that are due to obvious causes such as flu or heavy exercise.
Possible responses:
→ No / there's an obvious reason / don't know
→ Minor muscle soreness/tenderness in the past only
→ Major muscle soreness/tenderness in the past only
→ Current minor muscle soreness/tenderness
→ Current major muscle soreness/tenderness
Based on your response to this question, which may indicate history of tender muscles, tender muscles or very tender muscles, The Analyst™ will consider possibilities such as:
Allergy to Foods (Hidden)

Muscle pain can be due to food allergies.  Such pains will disappear after elimination of the offending foods from the diet.

Guillain-Barre Syndrome

Gradually muscle pain is experienced in the large muscles, such as the thighs, back and shoulders.  Pain in the lower back, buttocks or thighs is common, and is often the earliest symptom.  Deep, aching muscle pain is common.


Flu-like illness and muscle aches are generally present in cases of malaria.

Valley Fever (Coccidioidomycosis)

One third of patients with disseminated coccidioidomycosis have musculoskeletal involvement.

Concerned or curious about your health?  Try The Analyst™
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