Premenstrual Syndrome

What Causes Premenstrual Syndrome?

In order to deal properly with premenstrual syndrome we need to understand and — if possible — remove the underlying causes and risk factors.  We need to ask: "What else is going on inside the body that might allow premenstrual syndrome to develop?"

Diagnose your symptoms now!
  • let The Analyst™ find what's wrong
  • see your health summarized and in detail
  • have a doctor review your case (optional)

Accurate diagnosis of the factors behind premenstrual syndrome consists of three steps:

Step 1: List the Possible Causative Factors

Identify all disease conditions, lifestyle choices and environmental risk factors that can lead to premenstrual syndrome.  Here are five possibilities:
  • Copper Toxicity
  • Low Melatonin
  • Magnesium Need
  • Manganese Need
  • Low Progesterone

Step 2: Build a Symptom Checklist

Identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
forgetting dreams
eating during sleep hours
leg cramps caused by walking
elevated estrogen levels
being postmenopausal
hot flashes during & after period
jaundiced skin
difficulty falling asleep
elevated basophil count
current birth control pill use
unsound sleep
disturbed sleep
... and more than 40 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of premenstrual syndrome:
Cause Probability Status
Manganese Need 99% Confirm
Magnesium Need 13% Unlikely
Low Melatonin 4% Ruled out
Copper Toxicity 2% Ruled out
Low Progesterone 2% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate being premenopausal or being perimenopausal, The Analyst™ will ask further questions including this one:
Do you suffer from Premenstrual Syndrome (PMS)?
Possible responses:
→ No / don't know
→ Minor
→ Moderate
→ Serious
→ Severe
Based on your response to this question, which may indicate PMS, The Analyst™ will consider possibilities such as:
Low Melatonin Level

Melatonin can exhibit strong effects on the reproductive system, and the activity of the female hormones estrogen and progesterone is closely tied with its regulation of the sleep-wake cycle.  Abnormal biological rhythms and sleep-wake cycle disturbances are often a primary feature of periodic depression, another common characteristic of PMS.  Melatonin imbalances have been specifically linked to PMS.

A study reported finding that women with PMS had an earlier decline in melatonin secretion, resulting in a shorter overall secretion time.  "The data demonstrate that women with premenstrual syndrome have chronobiological abnormalities of melatonin secretion... The fact that these patients respond to treatments that affect circadian physiology, such as sleep deprivation and phototherapy, suggests that circadian abnormalities may contribute to the pathogenesis of premenstrual syndrome." [Arch Gen Psychiatr 1990;47(12): pp.1139-46]

Magnesium Requirement

Magnesium deficiency is strongly implicated as a causative factor in PMS.  Red Blood Cell magnesium levels in PMS patients have been shown to be significantly lower than in normal subjects.  The deficiency is characterized by a generalized hyperesthesia syndrome (with generalized aches and pains), and a lower premenstrual pain threshold.  One clinical trial of magnesium in PMS showed a reduction of nervousness in 89%, mastalgia in 96%, and weight gain in 95%.

Manganese Requirement

In a double blind study of women with normal menstrual cycles, lower dietary manganese (1.0mg versus 5.6mg) was found to increase mood and pain symptoms during the premenstrual phase. [Am J ObstetGynecol. 1993 May; 168(5): pp.1417-23]

Concerned or curious about your health?  Try The Analyst™
Symptom Entry
Symptom Entry
Diagnosis
Diagnosis
Suggestions
Suggestions
LifeMeter
LifeMeter®
Full Explanations
Explanations
Optional Doctor Review
Review (optional)
We use cookies for traffic analysis, advertising, and to provide the best user experience