In order to deal properly with premenstrual syndrome we need to understand and — if possible — remove the underlying causes and risk factors. We need to ask: "What else is going on inside the body that might allow premenstrual syndrome to develop?"
Accurate diagnosis of the factors behind premenstrual syndrome consists of three steps:
|Low Progesterone||3%||Ruled out|
|Manganese Need||3%||Ruled out|
|Low Melatonin||2%||Ruled out|
Do you suffer from Premenstrual Syndrome (PMS)?
Possible responses:→ No / don't know
Estrogen results in increased copper absorption. Copper is closely related to estrogen metabolism, so an imbalance can cause many female health problems such as premenstrual syndrome. Taking extra zinc and vitamin B6 before the menstrual period can reduce copper levels and thus the symptoms of PMS.
Melatonin can exhibit strong effects on the reproductive system, and the activity of the female hormones estrogen and progesterone is closely tied with its regulation of the sleep-wake cycle. Abnormal biological rhythms and sleep-wake cycle disturbances are often a primary feature of periodic depression, another common characteristic of PMS. Melatonin imbalances have been specifically linked to PMS.
A study reported finding that women with PMS had an earlier decline in melatonin secretion, resulting in a shorter overall secretion time. "The data demonstrate that women with premenstrual syndrome have chronobiological abnormalities of melatonin secretion... The fact that these patients respond to treatments that affect circadian physiology, such as sleep deprivation and phototherapy, suggests that circadian abnormalities may contribute to the pathogenesis of premenstrual syndrome." [Arch Gen Psychiatr 1990;47(12): pp.1139-46]
In a double blind study of women with normal menstrual cycles, lower dietary manganese (1.0mg versus 5.6mg) was found to increase mood and pain symptoms during the premenstrual phase. [Am J ObstetGynecol. 1993 May; 168(5): pp.1417-23]