Pernicious Anemia

Definition of Pernicious Anemia:

Anemia caused by vitamin B12 deficiency.  The body cannot make enough red blood cells due to lack of vitamin B12.

Topics Related to Pernicious Anemia

Addison's Disease

...the condition
“...Less commonly associated auto-immune diseases are insulin-dependent diabetes mellitus, and insufficiencies of the parathyroid glands, gonads, and vitamin B12 absorption (pernicious anemia).  There are no accurate statistics on the incidence of Addison's disease in the United States...”

Atrophic Gastritis

...relationship to Stomach Cancer
“Gastric cancer is 5 to 10 times more likely in those with chronic atrophic gastritis; the same increased incidence is also found in first-degree relatives of patients with gastric cancer and pernicious anemia.”
...relationship to Megaloblastic Anemia / Pernicious Anemia
“...Patients with antibodies to parietal cells (PCA) or intrinsic factor, or both, have atrophy of the fundal mucosa (Type A) and a very high rate of pernicious anemia, often associated with other autoimmune endocrine disorders...”
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More topics Related to Pernicious Anemia

CBC (Complete Blood Count) Test a treatment
“...In some anemias, such as pernicious anemia, the amount of variation (anisocytosis) in RBC size (along with variation in shape – poikilocytosis) causes an increase in the RDW...”


...related topic
“Essential for normal growth and functioning of all body cells, especially those of bone marrow (red blood cell formation), gastrointestinal tract and nervous system, it prevents pernicious anemia and plays a crucial part in the reproduction of every cell of the body i.e. synthesis of genetic material (DNA).”

Diabetes Type I

...relationship to Megaloblastic Anemia / Pernicious Anemia
“...The resulting inflammation and tissue damage reduces vitamin B12 absorption and may lead to Pernicious anemia, which occurs in approximately 1 in 50 adults with Type 1 Diabetes.”

Folic Acid a treatment
“...With both folic acid deficiency anemia and pernicious anemia, folic acid is usually supplemented along with vitamin B12...”


...the condition
“...Laboratory Findings ... Macrocytic anaemia due to pernicious anemia following atrophic gastritis of long duration...”


...the condition
“...Disorders such as iron deficiency anemia, pernicious anemia and other B-vitamin deficiencies, oral lichen planus, erythema multiforme, aphthous ulcer, pemphigus vulgaris, syphilis, and others...”


...relationship to Megaloblastic Anemia / Pernicious Anemia
Pernicious anemia is associated with other autoimmune conditions such as Hashimoto's disease, a form of hypothyroidism.”

Low White Blood Cell Count

...the condition
“...Neutropenia can occur in acute bacterial infections, viral infections, rickettsia disease, some parasite injections, aplastic and pernicious anemia, acute lymphoblastic leukemia, some hormone imbalances and anaphylactic shock.”


...related topic
“An abnormally large nucleated red blood cell found especially in people having pernicious anemia or certain vitamin deficiencies.”

Megaloblastic Anemia / Pernicious Anemia

...the condition
“...Eating extra yeast also seemed to relieve the symptoms of pernicious anemia, but the neurological symptoms of this disease either were not resolved or appeared later on, confirming some doctors' feelings that there were two different problems involved...”
...our question about Your serum iron level
“Elevated serum iron can occur as a result of pernicious anemia.”
...relationship to Alzheimer's Disease
Pernicious Anemia can be mistaken for Alzheimer's in older patients.”
...relationship to Chronic Thyroiditis
Pernicious anemia is more common in people who have other autoimmune diseases such as thyroiditis.”
...relationship to Vitamin B12 Requirement
“The main indicator of vitamin B12 deficiency is pernicious anemia, which in turn is due to a deficiency of intrinsic factor.”
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More topics Related to Pernicious Anemia

Multiple Sclerosis

...recommendation Test for B12 Levels
“...A vitamin B12 deficiency has very similar symptoms and is frequently misdiagnosed as MS; the type of anemia resulting from B12 deficiency is called pernicious anemia.  Additionally, researchers found in 45 MS patients that vitamin B12 levels were significantly lower in those who experienced the onset of first neurological symptoms prior to...”


...relationship to Megaloblastic Anemia / Pernicious Anemia
“Additional mental disturbances resulting from pernicious anemia include: loss of alertness, drive, self-confidence, and independence, social withdrawal, nervous irritability, headaches, insomnia, moodiness, severe agitation, lack of coordination...”

Stiff Man Syndrome

...the condition
“...Other autoimmune disorders such as diabetes, pernicious anemia (a chronic, progressive blood disorder), and thyroiditis (inflammation of the thyroid gland) may occur more frequently in patients with stiff-person syndrome...”

Stomach Cancer

...the condition
“...Pernicious anemia – this affects the lining of the stomach...”

Test for B12 Levels a treatment
“...Of pernicious anemia sufferers, 70% have these antibodies...”

Urinary Retention

...the condition
“...antihistamines, alcohol, and other pharmaceutical drugs; Conditions affecting the autonomic or peripheral nerve, including Autonomic Neuropathy, Diabetes Mellitus, Guillain-Barré Syndrome, Pernicious Anemia, Poliomyelitis, Spinal cord injury, Syphilitic infection of the spinal cord; Conditions affecting the brain, including Cardiovascular Disease, Multiple Sclerosis, Brain Tumor, Normal...”

Vitamin B12 (Cobalamine) a treatment
“...In the early to mid 1800s, an unrecognized vitamin B12 deficiency was referred to as pernicious anemia because it was almost always fatal...”


...the condition
“...Even though most people with vitiligo are in good general health, they are at greater risk of ... Pernicious anemia (vitamin B12 deficiency)...”
...relationship to Megaloblastic Anemia / Pernicious Anemia
“There is a particularly high incidence of vitiligo among individuals with pernicious anemia, and vice versa...”
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