Abdominal Distension, Swelling

What Causes Swollen, Enlarged, Or Distended Abdomen?

Swollen, enlarged, or distended abdomen can have various causes, ranging in severity from 'minor' to 'generally fatal'.  Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

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Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms.  In order to diagnose swollen, enlarged, or distended abdomen, we could:

  • Research the topic
  • Find a doctor with the time
  • Use a diagnostic computer system.
The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "swollen, enlarged, or distended abdomen" as a symptom.  Here are eight of many possibilities (more below):
  • Diverticular Disease
  • A Weight Problem
  • Kidney Stones
  • Crohn's Disease
  • Enlarged Spleen
  • Giardia
  • Hookworms
  • Constipation

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
kidney stones in family members
frequent unexplained nausea
painful urination
high dairy product consumption
rotten egg burps
occasional unexplained fevers
having loose stools
mild meal-induced pain
recent onset blood in urine
Crohn's disease in remission
weak urine stream
moderate hypogastric pain
... and more than 70 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of swollen, enlarged, or distended abdomen:
Cause Probability Status
Hookworms 92% Confirm
A Weight Problem 23% Unlikely
Kidney Stones 20% Unlikely
Enlarged Spleen 1% Ruled out
Diverticular Disease 1% Ruled out
Constipation 1% Ruled out
Giardia 1% Ruled out
Crohn's Disease 1% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate abdominal discomfort, The Analyst™ will ask further questions including this one:
Do you experience any abdominal swelling / distension that does not appear to be meal-, gas- or weight-related? In other words, is your abdomen larger than it should be?
Possible responses:
→ No / probably meal/gas/weight-related / don't know
→ Slight, comes and goes with or without meals
→ Slight, always present with or without meals
→ Significant, comes and goes with or without meals
→ Significant, always present with or without meals
Based on your response to this question, which may indicate either slight abdominal distension or significant abdominal distension, The Analyst™ will consider possibilities such as:
(Prescription) Drug Side-Effects

Certain medications, including those containing lactulose or sorbitol, may cause bloating.

Abdominal Hernia

A strangulated hernia may cause abdominal distension.


A study of 51 women, 26 with endometriosis and 25 without, found that a significantly larger proportion of women with endometriosis than control subjects experienced abdominal bloating (96% vs. 64%) [J Obstet Gynaecol Can.  2009 Dec; 31(12): pp1159-71]

Enlarged Lymph Nodes

Enlarged Lymph Nodes also suggests the following possibilities:

Hormone Imbalance

Hormonal fluctuations such as those occurring with pregnancy or at the start of a menstrual period (these raise progesterone levels) can slow down gut motility and cause food to pass more slowly through the digestive system, sometimes causing bloating and/or constipation.

Nutritional Deficiency

Low protein intake can manifest as edema of the hands and feet, swollen abdomen, irritability, anorexia, a peeling rash, hair discoloration, and a large fatty liver.  The abdominal swelling is due to (1) ascites caused by hypoalbuminemia and (2) an enlarged fatty liver.

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