Your Vitamin B6 Level

What Causes Abnormal Vitamin B6 Levels?

To successfully treat and prevent recurrence of abnormal vitamin B6 levels we need to understand and — if possible — remove the underlying causes and risk factors.  We need to ask: "What else is going on inside the body that might allow abnormal vitamin B6 levels to develop?"

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Accurate diagnosis of the factors behind abnormal vitamin B6 levels consists of three steps:

Step 1: List the Possible Causative Factors

Identify all disease conditions, lifestyle choices and environmental risk factors that can lead to abnormal vitamin B6 levels.  Here are two possibilities:
  • Pyroluria
  • Nutritional Deficiency Anemia

Step 2: Build a Symptom Checklist

Identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
no social support group
being prone to 'stitches'
lighter/paler skin color
moderate alcohol consumption
a few white spots on fingernails
chronic nausea
being an unsocial person
being a recovered alcoholic
forgetting dreams
sensitivity to bright light
joint pain/swelling/stiffness
severe fatigue after slight exertion
... and so on

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of abnormal vitamin B6 levels:
Cause Probability Status
Nutritional Deficiency Anemia 99% Confirm
Pyroluria 53% Possible
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate having had recent lab tests, The Analyst™ will ask further questions including this one:
Vitamin B6 (pyridoxine). Unit: ng/mL [nmol/L]
Possible responses:
→ Don't know
→ Confirmed deficiency in the past
→ Under 4 [16] (low)
→ 4 to 18 [16-73] (normal)
→ Over 18 [73] (elevated)
Based on your response to this question, which may indicate history of B6 deficiency, low B6 levels, normal B6 levels or high B6 levels, The Analyst™ will consider possibilities such as:

A functional pyridoxine deficiency is common in pyroluria (often seen in alcoholics), due not so much to inadequate intake as impaired conversion to its active form, pyridoxal-5-phosphate, and enhanced degradation.

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