Vitamin B1 (Thiamine)

Vitamin B1 (Thiamine): Overview

Alternative names: Thiamin, Vitamin B1 or Vitamin B-1.

Thiamine is an antioxidant nutrient that helps the body to inhibit the formation of the damaging free radicalsVitamin B1 chelates heavy metals such as lead.  It is effective in the treatment of uneven heartbeat, low blood pressure and chest pain.

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Deficiency may arise from lack of gastric acid.  Beriberi, the deficiency disease associated with inadequate thiamin intake, was first described in 1630 by the Dutch physician Bontius.  The use of polished rice and white flours as staples have lead to mild, but chronic deficiencies of thiamin; even in certain populations in the United States (especially alcoholics).


The best sources include brewer's yeast, rice husks (the part removed to make polished rice), wheat germ, sunflower and sesame seeds, peanuts, millet, grain husks, meat products, vegetables.  Vitamin B1 is destroyed by heat, sugar, alcohol, smoking.


Thiamine functions as a cofactor for several enzymes in the form of thiamine triphosphate (TPP).  TPP is also involved in a non-coenzymatic role in neuronal cells where it modulates chloride channels.


There is an absolute requirement for thiamin in the daily diet and the US RDA has set this at 1.5mg.  Thiamin is official in the U.S.P.

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Vitamin B1 (Thiamine):

Vitamin B1 (Thiamine) can help with the following:



Multiple Sclerosis

Dr. Fred Klenner, MD pioneered the use of injectable thiamine (vitamin B1) and injectable liver extract for the treatment of multiple sclerosis.  His experience and that of others is that early treatment is important in producing symptomatic relief and a state of well-being.

Myasthenia Gravis

To enhance acetylcholine levels take thiamine 100mg daily.  Additionally, Dr Fred Klenner, MD stresses the importance of thiamin in treating myasthenia gravis and recommends its use by injection.  From 30 years of experimentation he concludes that this is not a vitamin deficiency disease but one of several vitamin-dependent diseases, where the successful treatment requires dosages up to 1,000 times the minimal daily requirement that has been established for thiamin.


Painful Menstruation (Dysmenorrhea)

In a well-designed controlled trial of 556 girls with moderate to severe menstrual cramping, vitamin B1 (100mg daily by mouth) for 3 months produced startling results.  87% were cured, 8% were almost completely relieved, while only 5% were not benefited at all. [ Indian J Med Res May, 1996;103: pp.227-31]



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