Transferrin Saturation Test

Transferrin Saturation Test: Overview

The transferrin saturation test is a sensitive and relatively inexpensive biochemical measure of iron overloading.

Diagnose your symptoms now!
  • let The Analyst™ find what's wrong
  • identify any nutritional deficiencies
  • have a doctor review your case (optional)

Colds, inflammation, liver disease, and malignancies can falsely lower test values.


Transferrin is a blood protein that picks up iron absorbed by the intestines and transports it from one location to another.  When iron absorption is abnormally high, transferrin proteins become more saturated with iron.  An elevated test value therefore reflects an increase in iron absorption.


Several factors can falsely elevate test values, including the use of vitamin C, dietary supplements containing iron, medicinal iron, and estrogen preparations.  Patients should avoid these products for 24 hours prior to the fasting blood draw.  The placebos contained in some oral contraceptive packages may contain iron.  These iron-containing placebos should be avoided for 24 hours prior to the fasting blood draw.

On This Page

Transferrin Saturation Test:

Transferrin Saturation Test can help with the following:


Hemochromatosis (Iron overload)

The first step in working up a patient with suspected iron overload is the transferrin saturation measurement in a fasting blood draw.  Pathologic blood loss or a history of frequent blood donations should be considered reasons for normal iron status in patients who nevertheless have symptoms consistent with hemochromatosis.

Report by The Analyst™
Click to see sample report
Health problems rarely occur in isolation or for obvious reasons

Your body is a highly complex, interconnected system.  Instead of guessing at what might be wrong, let us help you discover what is really going on inside your body based on the many clues it is giving.

Our multiple symptom checker provides in-depth health analysis by The Analyst™ with full explanations, recommendations and (optionally) doctors available for case review and answering your specific questions.


Very useful: is highly recommended for
Very useful:
is highly recommended for
We use cookies for traffic analysis, advertising, and to provide the best user experience