Megaloblastic Anemia

Definition of Megaloblastic Anemia:

A condition in which the bone marrow produces large, abnormal, immature red blood cells (megaloblasts).  Anemia is a disorder in which the number of red blood cells is lower than normal.

Topics Related to Megaloblastic Anemia

Birth Control Pill Issues

...the condition
“...Birth control pills tend to cause folic acid depletion and increase the risk of cervical dysplasia and vascular thrombosis, stroke, and possibly megaloblastic anemia.  B-vitamins...”

Chemotherapy Side-Effects

...relationship to Megaloblastic Anemia / Pernicious Anemia
“Some chemotherapy agents are known inhibitors of folic acid enzymes and as such can induce a megaloblastic anemia.”
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More topics Related to Megaloblastic Anemia

Folic Acid Deficiency

...the condition
“...In pregnancy, this megaloblastic anemia is of great concern...”

Megaloblastic Anemia / Pernicious Anemia

...the condition
“...If either is lacking in the diet, or if the absorption of either is impaired, megaloblastic anemia may result...”
...relationship to Tapeworm Infection
“Signs of infection with large tapeworms (especially with the broad fish tapeworm, Diphyllobothrium latum) include conditions associated with vitamin B12 deficiency such as megaloblastic anemia.”
...relationship to Bacterial Dysbiosis
“Abnormal bacterial populations may consume cobalamin, contributing to B12 deficiency states and resulting in megaloblastic anemia.”
...recommendation Test for B12 Levels
“A vitamin B12 deficiency is the most common cause of megaloblastic anemia.  When testing facilities are not available or cannot be afforded, intramuscular or sublingual B12, with or without folic acid, can be used to see if symptoms improve...”
...recommendation Test Folic Acid Levels
“...CAUTION: It is always important to discover the underlying deficiency that is causing a megaloblastic anemia.  Higher doses of folic acid (greater than 1mg per day) may improve or mask the anemia caused by a B12 insufficiency...”
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More topics Related to Megaloblastic Anemia

Nutritional Deficiency Anemia

...the condition
“...Iron, vitamin B12 and folate deficiencies can also produce forms of nutritional anemia – Iron Deficiency Anemia and Megaloblastic Anemia.”

Tendency Toward Postpartum Depression

...the condition
“...When postpartum depression occurs with megaloblastic anemia, the depression many times responds extremely well to folate supplementation...”

Vitamin B12 Requirement

...our question about Vegetarian, vegan or raw-food diet
“...Vitamin B12 deficiency is the most common cause of megaloblastic anemia.  Both long-term low dietary consumption and poor absorption are responsible for the final outcome of a B12 deficiency, namely megaloblastic anemia and neurological symptoms...”
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