Definition of Collagen:

The primary protein within white fibers of connective tissue and the organic substance found in tendons, ligaments, cartilage, skin, teeth and bone.

Topics Related to Collagen

Alport Syndrome

...related topic
“Alport syndrome is caused by a mutation in a gene for collagen.  This inherited disorder is uncommon, affecting about 2 out of 10,000 people...”

Ankylosing Spondylitis

...the condition
“Ankylosing spondylitis is an autoimmune disease which affects collagen structures, specifically the joints between the vertebrae of the spine...”
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More topics Related to Collagen


...recommendation L-Proline
“Proline is involved in the structural repair of damaged collagen in arteriosclerotic blood vessels (hardened arteries).”
...recommendation Hawthorn Berry Extract
“...Proanthocyanadins stabilize collagen to prevent cholesterol deposits on arterial walls, prevent free radical damage, reduce peripheral vascular resistance, angina, cholesterol, and increase coronary and myocardial perfusion...”

Bilberry a treatment
“...The actions of concentrated extracts have been shown to be effective in stabilizing collagen, normalizing capillary permeability, preventing platelet aggregation, and relaxing smooth muscles among other things...”

Bioflavonoids a treatment
“...They assist Vitamin C in keeping collagen, the intercellular "cement" in healthy condition; are essential for the proper absorption and use of vitamin C; prevent Vitamin C from being destroyed in the body by oxidation; are beneficial...”

Carnosine a treatment
“...Carnosine helps to prevent skin collagen cross-linking which leads to loss of elasticity and wrinkles...”

Cigarette Smoke Damage

...relationship to Buerger's Disease
“...Recent work suggests that Buerger's disease may be a reaction to tobacco of persons with a specific genetic type or an autoimmune disorder with immune cell sensitivity to some collagen types, which are constituents of blood vessels.”

Collagen Vascular Disease

...the condition
Collagen vascular disease is a class of autoimmune disease that affects collagen...”
...recommendation Physical Therapy
“Physical therapy or gentle exercise can be used to treat collagen vascular disease...”


...related topic
“A disease affecting collagen.”

Concern Over Wrinkled Skin

...the condition
“...into two main layers: the exterior epidermis, including the stratum corneum ("horny" outer layer), and the dermis below, which contains capillaries, hair follicles, sebaceous glands and the fibers (collagen and elastin) that give the skin its strength and elasticity...”
...relationship to Cigarette Smoke Damage
“...It decreases the formation of collagen, the skin's main structural component, and may reduce the water content of the skin, all of which increase wrinkling...”
...recommendation Vitamin C (Ascorbic Acid)
“...Ascorbic acid increases the synthesis of collagen more than five-fold in cultures of human skin...”


...related topic
“...It is also involved with vitamin C in the formation of collagen and the proper functioning in central nervous system...”

Copper Deficiency

...the condition
“...Low copper levels may also affect collagen formation and thus tissue health and healing...”

Cosmetics / Moisturizers a treatment
“...Ingredients that are often added to moisturizers include lanolin (from sheep's wool, it may cause an allergic reaction), vitamins, essential fatty acids, collagen, elastin, and keratin...”


...related topic
“A protein that is similar to collagen and is the chief constituent of elastic fibers.”


...related topic
“...Fibroblasts produce collagen and elastin.”

Fluoride Toxicity

...relationship to Osteoporosis - Osteopenia
“Fluorides destroy collagen, which is the glue that adds strength to the bones.”

GLA (Gamma Linolenic Acid) a treatment
“...Ageing: GLA's anti-inflammatory and rejuvenating powers increase cell resilience and moisten the fatty layer beneath the skin, delivering a multitude of beautifying benefits such as ... combating collagen loss...”


...related topic
“...A natural antacid and sweetener, it is involved in the syntheses of DNA, phospholipids and collagen.”

Glycolic Acid a treatment
“...Once inside the cell, it stimulates the skin to make new, healthier collagen and elastin fibers in the deeper dermis, improving sun damage and wrinkling...”


...related topic
“...This protein cross-linking is characteristic of long-life proteins and is notable in the eye and in collagen.  It is likened to "rusting" of tissue and contributes to the aging process.”

Gotu Kola a treatment
“...Integumentary: Inflammations; burns (2nd & 3rd degree-topical & systemic usage); ulcers; leprous sores; cellulite; poor wound healing (topical); keloids; to Improve integrity of collagen matrix; help treat & reduce scarring after surgery; scleroderma; stimulates hair & nail growth; increases vascularization of connective tissue; increases mucin formation & structural...”

Gout / Hyperuricemia

...recommendation Increased Fruit/Vegetable Consumption
“...These compounds are flavonoid molecules that give these fruits their deep red-blue color, and are remarkable in their ability to prevent collagen destruction.”


...related topic
“Pink, fleshy overgrowth of capillaries and collagen within a wound.”

Grape Seed Extract a treatment
“...The actions of PCOs include decreasing capillary permeability (vitamin "P"), inhibiting the breakdown of collagen, and free radical scavenging...”

Hawthorn Berry Extract a treatment
“...Hawthorn is good for arthritis because it helps stabilize collagen, the protein found in joints that are destroyed by inflammatory diseases...”

Heparin a treatment
“...Some conditions that appear to be sensitive to heparin include ... Arthritis (Inhibits cell accumulation, collagen destruction and angiogenesis)...”

Hives (Urticaria)

...the condition
“...heat or sun, cold, light, pressure from bracelets and clothes or scratching, vibration, exercise; Secondary urticaria: infections (e.g. hepatitis B virus, candida albicans, streptococcal bacteria), collagen vascular diseases, autoimmune diseases or other metabolic disorders, cancer, psychological, hypothyroidism, polycythemia vera, protoporphyria (even without excessive sun exposure)...”

Hot Applications (Thermotherapy) a treatment
“...Whirlpool baths promote vasodilation and help stretch collagen tissue.  Ultrasound Therapy A method of applying deep heat to tissues using high-frequency sound waves...”

Hyperbaric Oxygen a treatment
“...Collagen deposition and synthesis depend on an oxygen-dependent prolyl-hydroxylase hydroxylation of proline...”
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More topics Related to Collagen

Hypertension (High Blood Pressure)

...the condition
“...This condition is associated with kidney disease (e.g. chronic glomerulonephritis or pyelonephritis, polycystic renal disease, collagen disease of the kidney, obstructive uropathy) or pheochromocytoma, Cushing's syndrome, primary aldosteronism, hyperthyroidism, myxedema, coarctation of the aorta, or renovascular disease...”

Increased Fruit/Vegetable Consumption a treatment
“...In test tube and animal studies, they have been shown to protect collagen, one of the most important components of capillary walls...”


...related topic
“A nodular, firm, movable, nonencapsulated, often linear mass of scar tissue, tender and frequently painful, consisting of wide, irregularly distributed bands of collagen, usually occurring after trauma, surgery, a burn, or severe acne, more common among people of African origin.”

L-Lysine a treatment
“...It is necessary for proper growth and helps form collagen which comprises bone cartilage and connective tissues...”

L-Proline a treatment
“Proline is a non-essential amino acid that aids in the production of collagen and helps reduce the loss of collagen due to the aging process...”

Mercury Toxicity (Amalgam Illness)

...relationship to Multiple Sclerosis
“...Mercury has long been linked to autoimmune diseases such as MS because of its affinity to attach to collagen tissue, which is the most common protein in the body...”

Mitral Valve Prolapse

...recommendation Magnesium
“...A magnesium deficiency ... hinders the mechanism by which fibroblasts degrade defective collagen (connective tissue abnormalities are common in mitral valve prolapse)...”

MSM (Methyl Sulfonyl Methane) a treatment
“...MSM provides an essential sulfur foundation that the body needs to form proteins and collagen (connective tissue), synthesize and activate vitamins, produce enzymes and immunoglobulin, and maintain the immune system...”


...recommendation Boron
“...It does alleviate and seems to cure arthritis either by acting against whatever organism may cause rheumatoid diseases and/or as a membrane catalyst that permits repair of damaged cartilage and collagen.”

Osteoporosis - Osteopenia

...recommendation Bone Density Scan
“...A new urine test utilizes the two most specific markers of bone resorption – the collagen crosslinks pyridinium/pyridinoline (PYD) and deoxypyridinium/deoxypyridinoline (DPYD or DPD) – to identify elevated levels of bone loss before excessive damage occurs...”

Platelet Aggregation (Clotting)

...the condition
“...Several organic substances may promote platelet clumping which include collagen, ADP, the catecholamines, certain immune complexes and fatty acids...”

Poor/Slow Wound Healing

...the condition
“...Granulation occurs, which means that special cells called fibroblasts make collagen to fill in the wound...”
...relationship to Alcohol-related Problems
“...Alcohol impairs the early inflammatory response; it inhibits wound closure, development of new blood vessels, and collagen production; it alters the protease balance at the wound site, which is needed to remove foreign matter and dead tissue; it decreases resistance to infectious microorganisms.”
...relationship to Low HGH (Human Growth Hormone)
“...HGH stimulates the production of collagen, which sticks wounds together, strengthens weakened tissue, gives skin more elasticity and helps wounds of the skin or bone heal faster and stronger.”
...recommendation Vitamin C (Ascorbic Acid)
“Vitamin C is crucial for the proper function of the enzyme protocollagen hydroxylase which produces collagen, the primary constituent of the granulation tissue that heals a wound and the key component in blood vessel walls...”
...recommendation Superoxide Dismutase
“...SOD should be supplemented to encourage new tissue to grow, to enhance collagen, and to reduce swelling...”
...recommendation Gotu Kola
“...Centella improves collagen formation and angiogenesis...”
...recommendation Topical Estrogen
“...Wound size, collagen levels, and fibronectin levels all improved with topical estrogen, indicating improved wound healing...”
...recommendation Copper
“...Copper supplementation enhances bone healing, working with vitamin C to create strong collagen, and creating cross-links in collagen and elastin that give strength to proteins...”
...recommendation L-Arginine
“...In a clinical study published in a major medical journal, arginine supplementation significantly increased the amount of reparative collagen synthesized at the site of a "standard wound" (an incision 5cm long and 1mm in diameter) made in healthy volunteers...”

Prolotherapy a treatment
“...Fibroblasts increase in number at the sites of injection and over the course of four to six weeks secrete a substance called collagen which is a very strong and relatively inelastic substance...”

Rheumatoid Arthritis

...recommendation Boron
“...It does alleviate and seems to cure arthritis either by acting against whatever organism may cause rheumatoid diseases and/or as a membrane catalyst that permits repair of damaged cartilage and collagen.”


...related topic
“...Collagen, the protein glue that holds us together, contains silicon in silanolate form...”

Silicone Breast Implant Problems

...the condition
“...Autoantibodies to collagen and extracellular matrix proteins and abnormalities of cell-mediated immunity have been found in women with silicone implants and not in controls...”

Sjogren's Syndrome

...the condition
“...Scleroderma causes the body to accumulate too much collagen, a protein commonly found in the skin...”

Sulfur Requirement

...the condition
“...Sulfur is also a constituent of bones, teeth, and collagen (the protein in connective tissue)...”

Threonine a treatment
“An essential amino acid, Threonine is anti-aging, helps form Elastin and Collagen, supports the immune system, produces antibodies, helps digestive and intestinal tract function, and boosts metabolism.”

Tonsil Stones

...the condition
“Alternative names: Tonsillolith, Tonsil Stone Tonsil stones are irregularly-shaped, whitish-yellow, very foul-smelling globs of calcium, collagen, mucus and bacteria that get caught in the back of the throat...”

Torn, weak, or Stretched Ligaments or Tendons

...the condition
“...The torn or strained ligament is really millions of tears of these strands which are molecules of collagen.  Loose ligaments allow the joint to move beyond its normal range of motion...”

Vitamin C

...related topic
“...Vitamin C is important for maintenance of bones, teeth, collagen and blood vessels (capillaries), enhances iron absorption and red blood cell formation, helps in the utilization of carbohydrates and synthesis of fats and proteins, aids in fighting...”

Vitamin C Requirement

...the condition
“...It helps the body build and maintain collagen; heal wounds and bruises; keep the immune system healthy; maintain healthy bones, teeth, gums, red blood cells, and blood vessels; repair bone fractures...”

Vocal Cord Paresis / Paralysis

...the condition
“...Several options are available, including injection with various substances such as collagen, silicone, or body fat...”
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