Although catechin is found in several plants, none contain sufficient amounts to reach the levels used in trials; thus, catechin supplements are needed.
Because of its potential to cause side-effects on rare occasions [Conn HO. Cyanidanol: will a hepatotrophic drug from Europe go west? Hepatology 1983;3: pp.121-3], catechin should be used only under medical supervision.
Catechin has helped people with acute viral hepatitis , as well as individuals with chronic hepatitis , though not all studies have found a benefit. A typical amount used in successful trials is 500-750mg three times per day.
 Blum AL, Doelle W, Kortum K, et al. Treatment of acute viral hepatitis with (+)-cyanidanol-3. Lancet 1977;2: pp.1153-5
 Suzuki H, Yamamoto S, Hirayama C, et al. Cianidanol therapy for HBs-antigen-positive chronic hepatitis: a multicenter, double-blind study. Liver 1986;6: pp.35-44
 Bar-Meir S, Halpern Z, Gutman M, et al. Effect of (+)-cyanidanol-3 on chronic active hepatitis: A double blind controlled trial. Gut 1985;26: pp.975-9
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