Monoamine Oxidase

Definition of Monoamine Oxidase:

An enzyme catalyzing the removal of an amine group from a variety of substrates, including norepinephrine and dopamine.  MAO inhibitors block the action of MAO, thus raising the levels of the monoamine neurotransmitters such as norepinephrine, epinephrine, dopamine, and serotonin – which have significant effects on mood and behavior.  Epinephrine, norepinephrine and serotonin are normally deactivated by MAO-A while dopamine and phenylethylamine are normally metabolized by MAO-B.

Also: MAO

Topics Related to Monoamine Oxidase

(Prescription) Drug Side-Effects

...our question about Your melatonin level
“Certain drugs, for example MAO inhibitors, Fluvoxamine and Desipramine, can increase melatonin levels.”

Addictions / Addictive Tendencies

...the condition
“...Do not take L-Tyrosine if using a MAO inhibitor drug...”
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More topics Related to Monoamine Oxidase


...related topic
“Literally, substances meant to oppose depressions or sadness, and generally heterocyclic types such as Elavil, MAO inhibitors like phenelzine, or lithium carbonate...”

Broad Beans a treatment
“...Broad beans should be avoided by those taking monoamine oxidase (MAO) inhibitors due to their high tyramine content...”


...relationship to Estrogens Low
“Low estrogen levels trigger the brain to release MAO, an enzyme in the brain which breaks down and destroys the neurotransmitter, serotonin...”

Ephedra (Ma Huang) a treatment
“...Individuals with heart conditions, high blood pressure or on MAO inhibitors (a class of antidepressants) should avoid the use of ephedra altogether...”

Hydrazine Sulfate a treatment
“...WARNING!  Hydrazine sulfate is a monoamine oxidase (MAO) inhibitor and is incompatible with tranquilizers, barbiturates, alcohol and other central nervous system depressants...”

Hypotension (Low Blood Pressure)

...the condition
“ any of the following ... Drug-induced, including alcohol toxicity, anesthesia, antianxiety agents, antihypertensives, calcium channel blockers, diuretics, general anesthetics, antiarrhythmics, monoamine oxidase inhibitors, narcotic analgesics, tranquilizers, vasodilators...”
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More topics Related to Monoamine Oxidase

Premenstrual Syndrome PMS A (Anxiety)

...the condition
“...Estrogens appear to affect mood by suppressing type A-monoamine oxidase (MAO) while enhancing type B-MAO...”


...the condition
“...Platelets deficient in MAO (monoamine oxidase); Schizophrenia can appear suddenly and without warning...”

Selegiline a treatment
“...Selegiline blocks the enzyme monoamine oxidase type B, which forms one of the metabolic pathways for dopamine in the brain...”

St John's Wort a treatment
“...The action of hypericin appears to be based on the its ability to inhibit monoamine oxidase inhibitors; a class of enzymes involved in serotonin degradation...”

Tyramine-containing Foods Avoidance a treatment
“...The authors of this study concluded that pizzas from large chain commercial outlets are safe for consumption with MAO inhibitors...”

Weight Loss a treatment
“...Also, your healthcare professional needs to be aware of any other medications you are taking or have taken within the last 14 days, especially monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil)...”
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