Monoamine Oxidase

Definition of Monoamine Oxidase:

Monoamine oxidases (MAOs) are a family of enzymes that catalyze the removal of an amine group from a variety of monoamines.  Type A (MAO-A) deactivates epinephrine, norepinephrine, and serotonin; MAO-B metabolizes dopamine and phenylethylamine.

MAO inhibitors are antidepressants that block the action of MAO, thus raising the levels of monoamine neurotransmitters such as norepinephrine, epinephrine, dopamine, and serotonin – which have significant effects on mood and behavior.

Also: MAO, MAO inhibitor, MAO inhibitors, MAO-A, MAO-B, Monoamine Oxidase Inhibitor, Monoamine Oxidase Inhibitors, Monoamine Oxidases

Topics Related to Monoamine Oxidase

(Prescription) Drug Side-Effects

...our question about Your melatonin level
“Certain drugs, for example MAO inhibitors, Fluvoxamine and Desipramine, can increase melatonin levels.”

Addictions / Addictive Tendencies

...the condition
“...Do not take L-Tyrosine if using a MAO inhibitor drug.  Gamma Amino Butyric Acid (GABA) – may help relax and reduce cravings...”
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More topics Related to Monoamine Oxidase


...related topic
“Literally, substances meant to oppose depressions or sadness, and generally heterocyclic types such as Elavil, MAO inhibitors like phenelzine, or lithium carbonate...”

Broad Beans a treatment
“...Broad beans should be avoided by those taking monoamine oxidase (MAO) inhibitors due to their high tyramine content...”


...relationship to Estrogens Low
“Low estrogen levels trigger the brain to release MAO, an enzyme in the brain which breaks down and destroys the neurotransmitter, serotonin...”

Ephedra (Ma Huang) a treatment
“...Individuals with heart conditions, high blood pressure or on MAO inhibitors (a class of antidepressants) should avoid the use of ephedra altogether...”

Hydrazine Sulfate a treatment
“...WARNING!  Hydrazine sulfate is a monoamine oxidase (MAO) inhibitor and is incompatible with tranquilizers, barbiturates, alcohol and other central nervous system depressants...”

Hypotension (Low Blood Pressure)

...the condition
“ any of the following ... Drug-induced, including alcohol toxicity, anesthesia, antianxiety agents, antihypertensives, calcium channel blockers, diuretics, general anesthetics, antiarrhythmics, monoamine oxidase inhibitors, narcotic analgesics, tranquilizers, vasodilators...”

Licorice Root a treatment
“...Licorice may interfere with corticosteroid medications and antidepressants known as MAO inhibitors.”
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More topics Related to Monoamine Oxidase

Premenstrual Syndrome PMS A (Anxiety)

...the condition
“...Estrogens appear to affect mood by suppressing MAO-A while enhancing MAO-B, resulting in increased levels of epinephrine, norepinephrine and serotonin (all normally deactivated by MAO-A) and decreased levels of dopamine and phenylethylamine (both...”

Premenstrual Syndrome PMS D (Depression)

...the condition
“...The depression in PMS-D patients is usually associated with low levels of biogenic amines in the synaptic vesicles of the Central Nervous System, most likely due to increased MAO-A levels as a result of decreased peripheral estrogen...”


...the condition
“...Platelets deficient in MAO (monoamine oxidase); Schizophrenia can appear suddenly and without warning...”

Selegiline a treatment
“...Selegiline blocks the enzyme monoamine oxidase type B, which forms one of the metabolic pathways for dopamine in the brain...”

St John's Wort a treatment
“...The action of hypericin appears to be based on the its ability to inhibit monoamine oxidase inhibitors; a class of enzymes involved in serotonin degradation...”

Tyramine-containing Foods Avoidance a treatment
“...The authors of this study concluded that pizzas from large chain commercial outlets are safe for consumption with MAO inhibitors.  However, they recommended caution when ordering from smaller outlets or with gourmet pizzas that may use aged cheeses...”

Weight Loss a treatment
“...Also, your healthcare professional needs to be aware of any other medications you are taking or have taken within the last 14 days, especially monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil)...”
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