Liver Enlargement

What Causes Enlarged Liver?

In order to hopefully treat and prevent recurrence of enlarged liver we need to understand and — if possible — remove the underlying causes and risk factors.  We need to ask: "What else is going on inside the body that might allow enlarged liver to develop?"

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Accurate diagnosis of the factors behind enlarged liver consists of three steps:

Step 1: List the Possible Causative Factors

Identify all disease conditions, lifestyle choices and environmental risk factors that can lead to enlarged liver.  Here are four possibilities:
  • Leukemia
  • Cancer In General
  • Sarcoidosis
  • Infectious Mononucleosis

Step 2: Build a Symptom Checklist

Identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
postauricular node problems
major joint pain/swelling/stiffness
much reduced sense of smell
frequent confusion/disorientation
painful axillary nodes
minor problem with cysts
resolved atypical recent headaches
excessive thirst
multiple painful inguinal nodes
very great unexplained weight loss
having a high fever
sweating mildly at night
... and more than 40 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of enlarged liver:
Cause Probability Status
Sarcoidosis 98% Confirm
Cancer In General 12% Unlikely
Leukemia 0% Ruled out
Infectious Mononucleosis 0% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate liver problems, The Analyst™ will ask further questions including this one:
Is your liver enlarged? This may have been diagnosed by a doctor, or you may be able to feel a lump/discomfort/pain when you press gently under your right ribcage.
Possible responses:
→ Don't know
→ No, confirmed normal
→ Possibly - I think I can feel it
→ Yes, confirmed slight enlargement
→ Yes, confirmed significant enlargement
Based on your response to this question, which may indicate normal sized liver, possible enlarged liver or enlarged liver, The Analyst™ will consider possibilities such as:
Cancer, General

The liver is a common site for metastatic cancer.

Infectious Mononucleosis - Mono

Mild enlargement of the liver may occur.

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