Trypsin: Overview

Trypsin, is a digestive enzyme that acts to degrade protein.

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Trypsin is one of the three principal digestive proteinases, the other two being pepsin and chymotrypsin.


Trypsin is a proteolytic enzyme formed from trypsinogen, when it is cleaved by the actions of peptidase.  Trypsinogen (an inactive form) is formed in the pancreas, while the conversion to trypsin takes place in the small intestines where trypsin acts to help digest proteins.

As a proteolytic enzyme, trypsin is found in digestive aids and other formulation where this enzymatic activity is desired.


Trypsin is partial to cleaving proteins at arginine and lysine amino acid residues.  Trypsin continues the process of digestion (which began in the stomach) in the small intestine where a slightly alkaline environment (about pH 8) promotes its maximal enzymatic activity.

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