Large Granular Lymphocyte
(LGL) Leukemia

Alternative names: T-cell Large Granular Lymphocyte Leukemia, Proliferation of large granular lymphocytes, LGL Leukemia, Tγ-lymphoproliferative Disorder, T-cell Chronic Lymphocytic Leukemia

LGL leukemia is a rare form of chronic leukemia in which the cancer cells are large and have features of either T-lymphocytes or Natural Killer Cells.  Most LGL leukemias are slow-growing, but a small number are more aggressive.

Treatment and Prevention

Drugs that suppress the immune system may be helpful, but aggressive cases are very hard to treat.

Prognosis

The 5-year survival rate is estimated to be around 90%.