Inflammation of the spleen, caused by a variety of conditions ranging from exposure to hemolytic chemicals, systemic infections lodged in the spleen, even cancer. Splenomegaly: For practical purposes a term interchangeable with splenitis, since neither will have the usual symptoms associated with inflammation. Splenomegaly is often associated with viral hepatitis, mononucleosis, typhoid fever and abnormally high levels of red blood cells or platelets.
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