Your Basophil Count

What Causes Abnormal Basophil Count?

Abnormal basophil count can have various causes, ranging in severity from 'minor' to 'generally fatal'.  Finding the true cause means ruling out or confirming each possibility – in other words, diagnosis.

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Diagnosis is usually a complex process due to the sheer number of possible causes and related symptoms.  In order to diagnose abnormal basophil count, we could:

  • Research the topic
  • Find a doctor with the time
  • Use a diagnostic computer system.
The process is the same, whichever method is used.

Step 1: List all Possible Causes

We begin by identifying the disease conditions which have "abnormal basophil count" as a symptom.  Here are eight of many possibilities (more below):
  • Tendency Toward Allergic Reactions
  • Crohn's Disease
  • Dermatitis Herpetiformis
  • Hypothyroidism
  • Hodgkin's Lymphoma
  • Low Progesterone
  • Myelofibrosis
  • Eczema

Step 2: Build a Symptom Checklist

We then identify all possible symptoms and risk factors of each possible cause, and check the ones that apply:
history of Hodgkin's lymphoma
frequent unexplained fevers
difficulty conceiving children
regular painful urge to defecate
missing outer third of eyebrows
significant amounts of occult blood
itchy/scaly nipples
swollen cervical nodes
brittle fingernails
slight afternoon/evening fatigue
poor cold weather tolerance
breast soreness during cycle
... and more than 90 others

Step 3: Rule Out or Confirm each Possible Cause

A differential diagnosis of your symptoms and risk factors finds the likely cause of abnormal basophil count:
Cause Probability Status
Low Progesterone 95% Confirm
Myelofibrosis 30% Unlikely
Dermatitis Herpetiformis 16% Unlikely
Hodgkin's Lymphoma 0% Ruled out
Hypothyroidism 0% Ruled out
Eczema 0% Ruled out
Tendency Toward Allergic Reactions 0% Ruled out
Crohn's Disease 0% Ruled out
* This is a simple example to illustrate the process

Arriving at a Correct Diagnosis

The Analyst™ is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end.

If you indicate having had recent lab tests, The Analyst™ will ask further questions including this one:
White Blood Cells - Basophil Percentage [fraction]
Possible responses:
→ Don't know
→ 0 to 2% [0.00-0.02] (normal)
→ 3 to 5% [0.03-0.05] (somewhat elevated)
→ 6 to 10% [0.06-0.10] (elevated)
→ Over 10% [0.10] (high)
Based on your response to this question, which may indicate normal basophil count, somewhat elevated basophil count, elevated basophil count or highly elevated basophil count, The Analyst™ will consider possibilities such as:
Chronic Myelogenous Leukemia (CML)

Basophil levels are normally very low, but a high basophil count can indicate a problem with the production and growth of blood cells in the bone narrow, as occurs in myeloproliferative disorders.

Eczema

Various chronic forms of dermatitis can increase basophil levels.

Progesterone Low or Estrogen Dominance

Increased estrogen can raise basophil levels.

Sinusitis

Chronic sinusitis can raise basophil levels.

... and also rule out issues such as:
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