Biopsy

Definition of Biopsy:

Removal of a sample of tissue from a living being for diagnosis.  A pathologist later uses a microscope to look for certain features, such as cancer cells, in the sample.  A fine-needle aspiration biopsy involves inserting a thin needle to remove a small amount of tissue, sometimes using CT or ultrasound to guide the needle.  A core biopsy involves obtaining a sample of tissue with a thick needle or by inserting a thin, lighted tube (laparoscope) into a small incision in the abdomen.  Another biopsy method is to remove tissue during an operation.

Topics Related to Biopsy

Adenomyosis

...the condition
“...20% of women have adenomyosis, the exact rate of incidence of adenomyosis is unknown because a diagnosis can be made only after a pathologist examines uterine wall samples obtained during surgery or biopsy...”

Alport Syndrome

...the condition
“...The diagnosis of Alport Syndrome is done by a careful family history and a kidney biopsy (examination of a small piece of tissue taken from the kidney)...”
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More topics Related to Biopsy

Anemia

...the condition
“...A bone marrow biopsy may also be required...”

Arrhythmias/Dysrhythmias

...relationship to Magnesium Requirement
“Myocardial magnesium was measured in 8 young patients (mean age 32) with ventricular tachycardia of less than 30 seconds in duration who underwent endomyocardial biopsy...”

Barrett's Esophagus

...the condition
“...Diagnosis and Tests: The premalignant lining of Barrett's esophagus can be seen at endoscopy and diagnosed by endoscopic biopsy...”
...relationship to Esophageal Cancer
“...If Barrett's esophagus is diagnosed, regular follow-up endoscopic biopsy evaluations are recommended for the early detection of changes that could lead to cancer...”

Bile Duct Cancer

...the condition
“...Diagnosis and Tests: In addition to a complete medical history and medical examination, diagnostic procedures for bile duct cancer may include ... Biopsy...”

Bladder Cancer

...the condition
“...The cystoscope can also take tissue samples for biopsy to determine whether cancer cells are present...”

Breast Cancer

...the condition
“...The definitive diagnosis of breast cancer can only be made by doing a surgical biopsy...”

Budd-Chiari Syndrome

...the condition
“...Physical examination may find that the liver is enlarged; further testing may include ... Liver biopsy, to confirm diagnosis and see if cirrhosis is present...”

Cancer, General

...recommendation Bacteria / Pathogen Testing by PCR
“An Infectious Agents in Cancer Panel (Blood or Tissue Biopsy) can test for the presence of Helicobacter pylori, Hepatitis B, Human Papilloma Virus (6, 11, 16, 18) and Epstein-Barr Virus (EBV)...”

Canker Sores (Aphthous Ulcers)

...relationship to Gluten Sensitivity / Celiac Disease
“...Gluten enteropathy had been excluded by biopsy in the patients who responded to the gluten-free diet...”

Carcinoid Cancer

...the condition
“...The diagnosis is not usually suspected prior to surgery but is then established by biopsy...”

Cardiomyopathy

...relationship to Magnesium Requirement
“Myocardial magnesium was measured in 8 young patients (mean age 32) with ventricular tachycardia of less than 30 seconds in duration who underwent endomyocardial biopsy...”

Cervical Dysplasia

...the condition
“...This can only be determined through biopsy...”

Chronic Lymphocytic Leukemia (CLL)

...the condition
“...The pattern of the lymphocytes in the biopsy of the marrow can be one useful factor in determining the probable rate of progression of the disease...”

Cirrhosis of the Liver

...the condition
“...A liver biopsy will confirm the diagnosis...”

Colon Cancer

...the condition
“...Diagnosis and Tests: Laboratory Findings ... Biopsy of colonic tumor is necessary for definitive diagnosis...”

Coronary Disease / Heart Attack

...recommendation Bacteria / Pathogen Testing by PCR
“A Cardiovascular Disease Panel (Blood or Tissue Biopsy) can test for the presence of Chlamydia pneumoniae, Mycoplasma pneumoniae, Helicobacter pylori, Cytomegalovirus (CMV) and Human Herpes Virus 6 (HHV-6)...”

Creutzfeldt-Jakob Disease

...the condition
“...The only way to confirm a diagnosis of CJD is by brain biopsy or autopsy...”

Dermatitis Herpetiformis

...the condition
“...Diagnosis and Tests: DH is diagnosed through a skin biopsy, which involves removing a tiny piece of skin near the rash and testing it for the IgA antibody...”

Dermatomyositis

...the condition
“...He or she will also take a small sample of tissue from the affected muscle (a muscle biopsy), to check for abnormalities...”

Diarrhea

...the condition
“...Endoscopy usually is more specific than X-ray studies because it allows direct inspection of the mucosa, detection of superficial lesions, and the ability to biopsy the mucosa...”

Eczema

...the condition
“...A skin lesion biopsy may be performed, but is not always required to make the diagnosis...”

Endometrial Cancer

...the condition
“...Diagnosis and Tests: Endometrial cancer can be diagnosed by using endometrial biopsy or by dilatation and curettage (D&C) of the uterus...”

Endometrial Hyperplasia

...the condition
“...Diagnosis and Tests: Diagnosis can only be made by a pathologist who examines a sample of tissue removed from the thickened lining by a sampling procedure such as endometrial biopsy or dilatation and curettage (D&C)...”

Enlarged Spleen

...the condition
“...Blood tests such as a CBC; Ultrasound; Abdominal film or CT scan; Bone marrow biopsy; Other tests to check for underlying disorders...”

Environmental Illness / MCS

...the condition
“...If serum levels are negative and suspicion is high, a fat biopsy must be performed to complete the diagnosis...”

Esophageal Cancer

...the condition
“...Diagnosis of esophageal cancer symptoms is usually conducted through an X-ray method known as the barium swallow, and may also include endoscopy along with a biopsy, and a CT scan of the chest and abdomen...”

Fatty Liver

...the condition
“...Your doctor can confirm the diagnosis with blood tests for liver function, and by performing a liver biopsy...”

Gallbladder Cancer

...the condition
“...As with most cancers, a biopsy can be used to confirm diagnosis...”

Gastritis

...the condition
“...Gastritis can be diagnosed by biopsy and specimen examination under a microscope, where the presence of increased white blood cells is seen...”

Gastroscopy

...related topic
“...The same instrument can be used to take a sample from any areas that look suspicious (biopsy) which are sent for examination in a laboratory...”

Glomerulonephritis

...our question about Foamy urine
“IgAN is suspected when protein and blood (visible or not) are found in the urine, and is ultimately diagnosed by biopsy...”

Headaches

...the condition
“...If your symptoms are suggestive your doctor will perform a blood test and possibly a biopsy (the removal of a small piece of tissue under local anaesthetic for testing)...”

Hemochromatosis (Iron overload)

...the condition
“...4% of African Americans who underwent liver biopsy during medical care delivery...”

Hepatitis

...the condition
“...Your provider will request a blood test, possibly a urine test and, in a few cases, a liver biopsy...”
...recommendation Lecithin / Choline
“...Signs of liver damage on biopsy were significantly reduced in this study...”

Hodgkin's Lymphoma

...the condition
“...The final diagnosis depends on a biopsy, in which a surgeon removes a sample of lymphatic tissue (part or all of a lymph node) so that a pathologist can examine it under a microscope to check for cancer cells...”

Intestinal Malabsorption Syndrome

...the condition
“...Intestinal biopsy may show mucosal villous atrophy, tumor, or inflammation...”

Iron Deficiency Anemia

...relationship to Gluten Sensitivity / Celiac Disease
“...Patients with both positive titers underwent intestinal biopsy, and in 10 patients (5%), results were positive for celiac disease...”

Kaposi's Sarcoma

...the condition
“...KS may be suspected if the characteristic skin lesions are present, but a biopsy (tissue sample) is usually necessary to confirm the diagnosis...”
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More topics Related to Biopsy

Leukemia

...the condition
“...If leukemia is suspected then the next step is bone marrow aspiration or biopsy...”

Liver Cancer

...the condition
“...MRI; Angiogram; Biopsy; If liver cancer is diagnosed, the stage – or extent – of the disease needs to be determined in order to plan the best treatment...”

Lupus, SLE (Systemic Lupus Erythematosus)

...the condition
“...Some criteria, such as a biopsy diagnosis of kidney lupus, can carry more weight...”

Lyme Disease

...recommendation Bacteria / Pathogen Testing by PCR
“A Lyme/Tick Panel (Blood or Tissue Biopsy) can test for the presence of Borrelia burgdorferi (Lyme Disease), Babesia microti (Babesiosis), Ehrlichia chaffeensis (Ehrlichiosis) and Rickettsia rickettsii (Rocky Mountain Spotted Fever)...”

Male Breast Cancer

...the condition
“...Biopsy may be needed for confirmation...”
...our question about Nipple discharge color
“...Although it may very well turn out to be nothing, it should always be followed up with mammography and biopsy if any mammographic abnormality is found...”

Male-Specific Cancer Screening

...as a treatment
“...Men with a high result may be advised to have a biopsy to find out if cancer is present...”

Mastocytosis

...the condition
“...diagnosed by the appearance of the skin (characteristic lesions that are dark-brown and fixed: urticaria pigmentosa), and confirmed by finding an abnormally high number of mast cells through a skin biopsy...”

Melanoma

...the condition
“...Contrary to circulating myths, hairy moles do NOT differentiate benign from malignant; incisional biopsy into melanoma does NOT spread the tumor...”

Mouth Cancer

...the condition
“...Diagnosis and Tests: A biopsy usually follows a visual check...”

Multiple Myeloma

...the condition
“...Bone marrow aspiration or bone marrow biopsy can detect an increase in the number of plasma cells in the bone marrow...”

Myelofibrosis

...the condition
“...Diagnosis and Tests: A complete blood count, blood smear, bone marrow biopsy, and genetic testing are the methods generally used to confirm a diagnosis and rule out other causes of the symptoms...”

Myeloproliferative Neoplasm

...the condition
“...Diagnosis and Tests: Bone marrow aspiration and biopsy with cytogenetic studies are required in most, but not all, patients...”

Nephrotic Syndrome

...the condition
“...In order to diagnose one of the kidney disorders which cause nephrotic syndrome, a small sample of the kidney (biopsy) will need to be removed for examination...”

Non-Hodgkin's Lymphoma

...the condition
“...A biopsy is needed to make a final diagnosis...”

Osteomyelitis

...the condition
“...Once a likely site of infection has been identified, a bone biopsy will identify the specific bacteria that are present...”

Osteonecrosis of the Jaw

...the condition
“...However, a bone biopsy of the affected area can show positive signs of jawbone inflammation...”

Pelvic Inflammatory Disease (PID)

...the condition
“...The doctor may also order other tests such as a sonogram, endometrial biopsy, or laparoscopy to distinguish between PID and other serious problems that may mimic PID...”

Pleurisy

...the condition
“...In addition, a sample of tissue (pleural biopsy) for microscopic analysis may be obtained if your doctor is concerned that the fluid collection may be caused by tuberculosis or cancer...”

Polycythemia Vera

...the condition
“...Rarely, a bone marrow biopsy is needed...”

Polymyositis

...the condition
“...A muscle biopsy is used to confirm the presence of muscle inflammation typical only of polymyositis...”

Prostate Cancer

...the condition
“...Biopsy...”

Psoriasis

...the condition
“...A piece of skin can be cut out (biopsy) and sent for pathology testing to be quite sure of the diagnosis...”

Rectal Cancer

...the condition
“...An abnormal Pap smear shows signs of excessive cell growth and is followed by a colposcopy – the internal examination of specific lesions or areas of cell growth for biopsy...”

Sarcoidosis

...the condition
“...Diagnosis and Tests: Types of testing for sarcoidosis include: CBC; chem-7 or chem-20; ACE levels; chest X-ray; lymph node biopsy; skin lesion biopsy; bronchoscopy; open lung biopsy; gallium scan; nerve biopsy...”

Seizure Disorder

...relationship to Gluten Sensitivity / Celiac Disease
“...In a second group of 9 patients, celiac disease was not recognized because of mild or absent symptoms, but the diagnosis was confirmed by jejunal biopsy...”

Sjogren's Syndrome

...the condition
“...One is generally considered to have definite Sjogren's if one has dry eyes, dry mouth, and a positive lip biopsy...”

Soft Tissue Sarcoma

...the condition
“...However, the only way to confirm the diagnosis is with a biopsy...”

Steatorrhea

...the condition
“...Structural abnormalities of the small bowel are detected by barium studies and/or biopsy...”

Stomach Cancer

...the condition
“...Laboratory Findings ... Gastroscopic biopsy and cytology – essential for diagnosis...”

Test for Gluten Sensitivity

...as a treatment
“...The following tests can be ordered when trying to determine a patient's sensitivity to gluten ... Intestinal biopsy (for detecting suspected celiac disease, but is also prone to false negative results)...”

Test for Parasites

...as a treatment
“...Sometimes a biopsy of the small intestines is taken, a small amount of tissue that is examined for parasitic infestation...”

Test Histamine Levels

...as a treatment
“...Possibilities are: skin tests, RAST, or challenge tests; biopsy and/or CT scan...”

Thymoma

...the condition
“...Doctors can usually tell by taking a tissue sample (biopsy) and looking at it under a microscope...”

Thyroid Cancer

...the condition
“...An ultrasound may also be used to help find the thyroid lump during a needle biopsy...”

Toxoplasmosis

...the condition
“...Diagnosis and Tests: Diagnosis involves looking for toxoplasmosis antibodies in the blood, a CT scan of the brain, an MRI of the head, a slit-lamp examination of the eyes, and/or brain biopsy...”

Trichinosis

...the condition
“...Diagnosis and Tests: Common tests ... Muscle biopsy (trichinella cysts are seen in the muscle)...”

Ulcerative Colitis

...the condition
“...Laboratory findings ... Definitive diagnosis requires a colonic mucosal biopsy...”

Vaginal Dryness

...recommendation Korean Ginseng
“...When examined microscopically, the biopsy specimens showed typical atrophy, with thinned epithelial layer and little to no mucous production...”

Yeast / Candida Infection

...recommendation Bacteria / Pathogen Testing by PCR
“A Panfungal Panel (Blood or Tissue Biopsy) can test for the presence of several hundred human pathogenic fungal species...”
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