Have you used proton pump inhibitors (PPIs) such as Prilosec (Nexium) or Prevacid?
Possible responses:→ No / don't know
→ Minor use in the past
→ Significant use in the past
→ Currently using for up to 6 months
→ Currently using for over 6 months
Research suggests that gastritis and ulcers are triggered by bacterial overgrowth, rather than by stomach acidity. Long-term treatment of patients with potent acid blockers (proton pump inhibitors) which produce a more alkaline environment that is unfriendly to acid-tolerant bacteria such as Helicobacter pylori, may actually allow the overgrowth of other types of bacteria in the stomach, including Lactobacillus, Enterobacter, Staphylococcus and Propionibacterium which can result in inflammation, gastritis and ulceration. [Gastroenterology, Jan 2002]
Prilosec (omeprazole) has been shown to decrease B12 absorption.
Gastric acid secretion plays an important role in the regulation of zinc absorption in men. Drugs that keep stomach pH values of 3 or greater for at least 24 hours may predispose individuals to zinc deficiency.