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Glossary: Dihydrotestosterone
 


Definition
A highly active form of testosterone, which influences many aspects of manly behavior, from sex drive to aggression. The conversion from testosterone to DHT is driven by an enzyme called 5-alpha reductase, which is produced in the prostate, various adrenal glands, and the scalp.

Also: DHT

Topics Related To Dihydrotestosterone
Enlarged ProstateThe Condition
"...Another theory focuses on dihydrotestosterone (DHT), a substance derived from testosterone in the prostate, which more actively stimulates prostate growth..."

Recommendation Zinc
"...Zinc has been found to inhibit the activity of 5-alpha reductase, the enzyme that irreversibly converts testosterone to dihydrotestosterone, a form which binds more avidly to the prostrate and stimulates greater growth..."

Recommendation Saw Palmetto
"...This enzyme converts the hormone testosterone to DHT..."

Erectile Dysfunction (ED, Impotence)

Recommendation Test for Hormones
"...When considering lab testing, a full panel of tests should be considered such as DHEA, testosterone (total and free), DHT, sex hormone binding globulin (SHBG), estradiol, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (best taken at 9am to avoid diurnal variations), progesterone and a PSA test..."

Female Hair Loss

The Condition
"...Most modern medical research leans toward the position that a male hormone called dehydrotestosterone (DHT), which is converted from testosterone, binds to sites on hair follicles and is a primary instigator of hair loss..."

Male Hair Loss

The Condition
"...Most modern medical research leans toward the position that a male hormone called dehydrotestosterone (DHT), which is converted from testosterone, binds to sites on hair follicles and is a primary instigator of hair loss..."

Recommendation Saw Palmetto
"This extract has been found to counteract the conversion of testosterone to DHT by inhibiting DHT binding to cellular and nuclear receptor sites, thereby increasing DHT breakdown..."

Polycystic Ovary Syndrome (PCOS)

The Condition
"...It competitively inhibits intracellular dihydrotestosterone receptors within the hair follicles..."

Prostate Cancer

Recommendation DIM (di-indolmethane)/I3C (Indole-3-Carbinol)
"...DIM also inhibited dihydrotestosterone (DHT) stimulation of DNA synthesis in the androgen-dependent cancer cells..."

Yeast / Candida Infection

Recommendation GLA (Gamma Linolenic Acid)
"GLA can help reduce candida-induced hair loss by suppressing conversion of testosterone to its derivative DHT, in the hair follicles..."





Last updated: Dec 06, 2007


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