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Senile Dementia
  Senile Dementia
 Signs, symptoms, indicators
 Conditions that suggest it
 Contributing risk factors
 Conditions suggested by it
 Treatment recommendations
 Prevention
 


Senile dementia is a disease caused by degeneration of the brain cells. It is different from normal senility in the elderly in that the patient's brain function will gradually deteriorate resulting in progressive loss of memory and mental abilities, and noticeable personality changes. Causes & Development


Dementia is always caused by an underlying disease or condition. Brain tissue is damaged, and functioning is diminished. The most common cause of dementia is Alzheimer's disease, a progressive brain disorder causing deterioration in memory and thought processes.

Causes include:
  • Huntington disease, a progressive degenerative disease that causes dance-like movements and mental deterioration
  • Atherosclerosis, or hardening of the arteries
  • Multiple sclerosis, a disorder of the sheath that lines the brain and spinal cord
  • HIV, the immunodeficiency disorder that leads to AIDS
  • Parkinson's disease, a degenerative disorder of part of the nervous system
  • Creutzfeld-Jakob disease, a rapidly progressing degenerative disorder of the nervous system causing problems with walking, talking, and the senses
  • Pick's disease, a disorder of the brain that causes slowly progressing dementia
  • Viral or bacterial encephalitis, an inflammation of the brain
  • Lewy body disease, a degenerative disease of the nervous system
  • Normal pressure hydrocephalus, or increased cerebrospinal fluid in the brain
  • Chronic subdural hematoma, or bleeding between the brain lining and brain tissue
  • Brain tumor
  • Wilson disease, a rare disease causing an accumulation of copper in the liver, brain, kidneys, and corneas
  • Neurosyphilis, an infection of the nervous system by the syphilis bacteria, which causes weakness and mental deterioration
  • Progressive supranuclear palsy, also known as Steele-Richardson-Olszewski syndrome, a rare disorder of late middle age that causes widespread neurological problems.
Certain abnormalities of a person's metabolism or hormones may also be responsible for the development of dementia, including the following: In some of these cases, dementia can be reversed by removing the toxic agent or bringing vitamin levels back to normal.

Signs & Symptoms
Symptoms at the early stage include the following:
  • Forgetting recent events (distant memories also fade as the disease progresses)
  • Experiencing difficulty in reasoning, calculation, and accepting new things
  • Becoming confused over time, place and direction
  • Impaired judgment
  • Changes in personality
  • Becoming passive and losing initiative.
Symptoms at the middle stage include the following:
  • Losing cognitive ability, such as the ability to learn, judge, and reason
  • Becoming emotionally unstable, and easily losing temper or becoming agitated
  • Needing help to simply live from day to day
  • Confusing night and day; disturbing others' normal sleeping time.
Symptoms at the later stage include the following:
  • Losing all cognitive ability
  • Becoming entirely incapable of self-care, including eating, bathing, and so on
  • Neglecting personal hygiene
  • Incontinence
  • Losing weight gradually
  • Walking unsteadily and becoming confined to bed.
Treatment & Prevention
Senile dementia that is caused by depression, poor nutrition, thyroid dysfunction, drug poisoning, alcoholism, and so on, can often be corrected by treating the underlying problem.

Alzheimer's disease and multi-infarct dementia are degenerative diseases, and up to now there is no effective treatment. It is best to recognize the symptoms early and be diagnosed and assessed by a doctor. There are currently some medications available to slow the progress of Alzheimer's disease.

If you recognize the symptoms of senile dementia in a family member, these steps should be taken:
  • Consult your doctor to confirm the diagnosis.
  • Join a family support group for senile dementia patients. This will help to ease the pressure of looking after the patient through sharing of experience.
  • Take advantage of social services such as day care centers for the elderly.
  • Explain your loved one's illness to your relatives and neighbors to gain their understanding and support.
  • Make alterations in your home environment to prevent accidents.
  • Establish a daily routine for the patient to reduce his or her feelings of confusion.
  • Have the patient wear a wrist bracelet labeled with his name and telephone number. Always have a recent photo of the patient at home so that it will help to find him if he or she gets lost.
There is up till now no effective way to prevent Alzheimer's disease. However, multi-infarct dementia is caused by damaged blood vessels, and can be prevented through healthy living habits.





Signs, symptoms & indicators of Senile Dementia:
Symptoms - Mind - General  Occasional/frequent confusion/disorientation

Conditions that suggest Senile Dementia:
Aging  Parkinson's Disease
 Memory impairment and cognitive dysfunction are rarely encountered in early stage Parkinson's disease. However, about 30% of Parkinson's disease victims eventually develop Alzheimer's disease or other forms of dementia.

Symptoms - Mind - General

  Senile dementia (confirmed)

Risk factors for Senile Dementia:
Addictions  Alcohol-related Problems
 Alcoholism is a possible cause of senile dementia.

Childhood

  Down's Syndrome
 Although many people with Down's syndrome do develop dementia in their later years, this is by no means inevitable. Research indicates that although the incidence of dementia in people with Down's syndrome is similar to that of the general population, it occurs some 20-30 years earlier.

Circulation

  Stroke
 Multi-infarct dementia is caused by a series of minor strokes. It usually results from damage to the small blood vessels in the brain causing deprivation of blood supply to the brain cells thus affecting its function. Patients' abilities will decline in a step-like pattern.

  Atherosclerosis
 Atherosclerosis is a risk factor for reduced circulation in the brain, sometimes called ischemic vascular dementia (IVD).

  Hypertension
 Hypertension is a risk factor for reduced circulation in the brain, sometimes called ischemic vascular dementia (IVD).

Diet

  Consequences of Poor Diet
 Poor nutrition is one possible cause of senile dementia.

Drug Side-Effects

  (Prescription) Drug Side-Effects
 Drug poisoning can cause senile dementia.

Mental

  Depression

Symptoms - Glandular

  Poorly controlled diabetes
  Reasonably controlled diabetes
 Hypertension, diabetes and heart disease are risk factors for reduced circulation in the brain, sometimes called ischemic vascular dementia (IVD).

Symptoms - Mind - General

  Suspected senile dementia

Senile Dementia suggests the following may be present:
Circulation  Hypertension
 Hypertension is a risk factor for reduced circulation in the brain, sometimes called ischemic vascular dementia (IVD).

Recommendations and treatments for Senile Dementia:
Botanical  Ginkgo Biloba

Hormone

  DHEA

Nutrient

  NADH
 Because of its potential to stimulate endogenous L- DOPA synthesis, 17 patients in one study with symptoms ranging from mild cognitive decline to severe dementia received oral NADH as the disodium salt 10mg in the morning 30 minutes before breakfast. All showed a significant improvement in mental function within 8-12 weeks.

  Meyer's Cocktail

Preventive measures against Senile Dementia:
Diet  Alcohol Avoidance

Habits

  Tobacco Avoidance
 The best way to prevent multi-infarct dementia is to avoid smoking and alcohol, maintain a balanced diet, take regular exercise, have a positive attitude, and keep high blood pressure and diabetes under control.

  Aerobic Exercise


KEY
Weak or unproven link
Strong or generally accepted link
Proven definite or direct link
May do some good
Highly recommended


GLOSSARY

AIDS
Acquired Immune Deficiency Syndrome. An immune system deficiency disorder that suddenly alters the body's ability to defend itself. The AIDS virus invades the T4 helper/inducer lymphocytes and multiplies, causing a breakdown in the body's immune system, eventually leading to overwhelming infection and/or cancer, with ultimate death.

Alzheimer's Disease (Alzheimer's)
A progressive disease of the middle-aged and elderly, characterized by loss of function and death of nerve cells in several areas of the brain, leading to loss of mental functions such as memory and learning. Alzheimer's disease is the most common cause of dementia.

Arterial (Arteries, Artery)
Blood that leaves the heart. When it leaves the right ventricle, it is venous blood; and when it leaves the left ventricle, through the aorta, it is fresh and oxygenated. After it has passed out to the capillaries and started to return, it is venous blood.

Atherosclerosis
Common form of arteriosclerosis associated with the formation of atheromas which are deposits of yellow plaques containing cholesterol, lipids, and lipophages within the intima and inner media of arteries. This results in a narrowing of the arteries, which reduces the blood and oxygen flow to the heart and brain as well as to other parts of the body and can lead to a heart attack, stroke, or loss of function or gangrene of other tissues.

Bacteria (Bacterial, Bacterium)
Microscopic germs. Some bacteria are "harmful" and can cause disease, while other "friendly" bacteria protect the body from harmful invading organisms.

Chronic (Chronicity)
Usually referring to chronic illness: Illness extending over a long period of time.

Cobalamin (B12, B-12, Cobalamine, Vitamin B12)
Essential for normal growth and functioning of all body cells, especially those of bone marrow (red blood cell formation), gastrointestinal tract and nervous system, it prevents pernicious anemia and plays a crucial part in the reproduction of every cell of the body i.e. synthesis of genetic material (DNA).

Copper
An essential mineral that is a component of several important enzymes in the body and is essential to good health. Copper is found in all body tissues. Copper deficiency leads to a variety of abnormalities, including anemia, skeletal defects, degeneration of the nervous system, reproductive failure, pronounced cardiovascular lesions, elevated blood cholesterol, impaired immunity and defects in the pigmentation and structure of hair. Copper is involved in iron incorporation into hemoglobin. It is also involved with vitamin C in the formation of collagen and the proper functioning in central nervous system. More than a dozen enzymes have been found to contain copper. The best studied are superoxide dismutase (SOD), cytochrome C oxidase, catalase, dopamine hydroxylase, uricase, tryptophan dioxygenase, lecithinase and other monoamine and diamine oxidases.

Dementia (Senile Dementia)
An acquired progressive impairment of intellectual function. Marked compromise exists in at least three of the following mental activity spheres: memory, language, personality, visuospatial skills, and cognition (i.e. abstraction and calculation).

Diabetes Mellitus (Diabetes, Diabetic, Diabetics)
A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.

Endogenous
From within the body, either a native function or the product of the extended colony. Normal flora in the colon are considered endogenous.

Gland (Glands)
The glandular system is one of the most important and complicated systems of the body. Gland tissue can be either an organ or general tissue that secretes chemicals and there are two types of gland: exocrine and endocrine. Those glands which secrete chemicals through tubules or ducts are called exocrine and include sweat, tear and salivary glands. Ductless glands - part of the endocrine system - secrete special chemicals (hormones) directly into the blood.

Hematoma
Localized blood clot within an organ or tissue.

Hormones (Hormone)
Chemical substances secreted by a variety of body organs that are carried by the bloodstream and usually influence cells some distance from the source of production. Hormones signal certain enzymes to perform their functions and, in this way, regulate such body functions as blood sugar levels, insulin levels, the menstrual cycle, and growth. These can be prescription, over-the-counter, synthetic or natural agents. Examples include adrenal hormones such as corticosteroids and aldosterone; glucagon, growth hormone, insulin, testosterone, estrogens, progestins, progesterone, DHEA, melatonin, and thyroid hormones such as thyroxine and calcitonin.

Human Immunodeficiency Virus (HIV)
A retrovirus associated with onset of advanced immunodeficiency syndrome (AIDS).

Hypertension
High blood pressure. Hypertension increases the risk of heart attack, stroke, and kidney failure because it adds to the workload of the heart, causing it to enlarge and, over time, to weaken; in addition, it may damage the walls of the arteries.

Hyperthyroidism (Hyperthyroid)
An abnormal condition of the thyroid gland resulting in excessive secretion of thyroid hormones characterized by an increased metabolism and weight loss.

Hypothyroidism (Hypothyroid)
Diminished production of thyroid hormone, leading to low metabolic rate, tendency to gain weight, and sleepiness.

Incontinence (Incontinent)
The inability to retain urine in the bladder for a reasonable length of time. It is can be caused by urethral irritation, loss of tone to the basement muscle of the bladder (the trigone), scarification or growths on the urethral lining, nerve damage, or emotional stress.

Ischemia (Ischemic)
Localized tissue anemia due to obstruction of the inflow of arterial blood. A decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels.

Kidneys (Kidney, Renal)
Bean-shaped organs, each about the size of a fist. They are located near the middle of the back, just below the rib cage. The kidneys are sophisticated reprocessing machines, each day handling about 50 gallons of blood to sift out about half a gallon of waste products and extra water. The waste and extra water become urine, which flows to the bladder through tubes called ureters. The actual filtering occurs in tiny units inside the kidneys called nephrons. Every kidney has about a million nephrons. In a nephron, a glomerulus -- which is a tiny blood vessel, or capillary -- intertwines with a tiny urine-collecting tube called a tubule. A complicated chemical exchange takes place, as waste materials and water leave your blood and enter your urinary system. The kidneys recycle chemicals such as sodium, phosphorus, and potassium and thus regulate their levels. Renal: Pertaining to the kidneys.

Liver (Hepatic)
The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.

Metabolism (Metabolic, Metabolize, Metabolizes, Metabolizing)
The chemical processes of living cells in which energy is produced in order to replace and repair tissues and maintain a healthy body. Responsible for the production of energy, biosynthesis of important substances, and degradation of various compounds. Also defined as the sum total of changes in an organism in order to achieve a balance (homeostasis): Catabolic burns up, anabolic stores and builds up; the sum of their work is metabolism.

Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.

Multiple Sclerosis (MS)
Demyelinating disorder of the central nervous system, causing patches of sclerosis (plaques) in the brain and spinal cord, manifested by loss of normal neurological functions, e.g. muscle weakness, loss of vision, and mood alterations.

Nervous System
A system in the body that is comprised of the brain, spinal cord, nerves, ganglia and parts of the receptor organs that receive and interpret stimuli and transmit impulses to effector organs.

Niacin (B3, B-3, Niacinamide, Vitamin B3)
A coenzyme B-complex vitamin that assists in the breakdown of carbohydrates, fats and proteins. Essential for the health of the skin, nerves, tongue and digestive system. It is found in every cell of the body and is necessary for energy production. Niacin is also needed for DNA formation.

Parkinson's Disease (Parkinson's)
A chronic, slowly-progressing disease of the nervous system characterized clinically by the combination of tremor, rigidity, extreme slowness of movement, and stooped posture. It is characterized pathologically by loss of dopamine in the substantia nigra.

Steroid (Steroids)
Any of a large number of hormonal substances with a similar basic chemical structure containing a 17-carbon 14-ring system and including the sterols and various hormones and glycosides.

Syndrome
A medical condition characterized by a collection of related symptoms (what the patient feels) and signs (what a doctor can observe or measure).

Syphilis
A sexually-transmitted disease, with symptoms in the early contagious stages being a sore on the genitalia, a rash, patches of flaking tissue, fever, a sore throat, and sores in the mouth or anus.

Thiamine (B1, B-1, Thiamin, Vitamin B1)
A B-complex vitamin that acts as a coenzyme necessary for the conversion of carbohydrates into glucose, which is burned in the body for energy. It is essential for the functioning of the nervous system.

Thyroid (Thyroid Gland)
The thyroid gland is an organ with many veins, anchored around the front of the throat near the voice box. It is essential to normal body growth in infancy and childhood. It absorbs iodine from the diet and releases thyroid hormones - iodine-containing compounds that help govern the rate of the body's metabolism (its total life processes), affecting body temperature, and regulating protein, fat and carbohydrate catabolism in all cells. They keep up growth hormone release, skeletal maturation, and heart rate, force, and output. They promote central nervous system growth, stimulate the making of many enzymes, and are necessary for muscle tone and vigor. To a high degree, metabolism is regulated by the hormone thyroxine, which can be made by the thyroid if enough organic iodine is available. An enlarged thyroid gland that is not cancer is sometimes called goitre.

Vascular Dementia
Mental incapacity due to inadequate blood flow to the brain.




Last updated: Apr 27, 2008


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