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Heavy metal toxicity is a very general subject and people experience widely varying symptoms in response to heavy metal poisoning.
There are many individual metals causing varying degrees of illness based on acute and chronic exposures. Heavy metals is the term used for a group of elements that have particular weight characteristics. They are on the "heavier" end of the periodic table of elements. Some heavy metals - such as cobalt, copper, iron, manganese, molybdenum, vanadium, strontium, and zinc - are essential to health in trace amounts. Others are non-essential and can be harmful to health in excessive amounts. These include cadmium, antimony, chromium, mercury, lead, and arsenic - these last three being the most common in cases of heavy metal toxicity.
Causes & Development Sources of toxicity can include environmental, water supply, industrial, hobbies, and others, thus a full history of the person's work and living habits can help pinpoint potential heavy metal sources.
Causes of arsenic toxicity include ingestion of arsenic (found in insect poisons), skin contact (e.g. some linseed oils) and even drinking water.
Signs & Symptoms As an example of the scope of a heavy metal's toxicity, lead can affect the nervous system, gastrointestinal system, cardiovascular system, blood production, kidneys, and reproductive system.
Symptoms of heavy metal toxicity include mental confusion, pain in muscles and joints, headaches, short-term memory loss, gastrointestinal upsets, food intolerances/allergies, vision problems, chronic fatigue, and others. The symptoms are so vague that it is difficult to diagnose based on symptoms alone.
Arsenic Symptoms include nausea or vomiting, abdominal pain, diarrhea, garlic odor on breath, excessive salivation, headache, vertigo, fatigue, paresthesia, paralysis, kidney failure, progressive blindness, and mental impairment. Signs include mottled brown skin, hyperkeratosis (increased pigmentation) of palms and soles, cutis edema, transverse striate Leukonychia, perforation of nasal septum, eyelid edema, coryza, limb paralysis and reduced deep tendon reflexes. Mental symptoms include apathy, dementia, and anorexia.
Lead Signs and Symptoms include combinations of gastrointestinal complaints, hypertension, fatigue, hemolytic anemia, abdominal pain, nausea, constipation, weight loss, peripheral neuropathy, cognitive dysfunction, arthralgias, headache, weakness, convulsions, irritability, impotence, loss of libido, depression, depression of thyroid and adrenal function, chronic renal failure, gout. A patient with lead poisoning may have a combination of symptoms - or no symptoms at all until the condition has progressed. Mental symptoms include restlessness, insomnia, irritability, confusion, excitement, anxiety, delusions, and disturbing dreams.
Mercury Mercury toxicity has been linked to, among other things, mercury dental fillings, particularly when people have a large number of them. Symptoms include a metallic taste in the mouth, excess salivation, gingivitis, tremors, stomach and kidney troubles. Mental symptoms include shyness, irritability, apathy and depression, psychosis, mental deterioration, and anorexia.
Diagnosis & Tests If a specific diagnosis cannot be made, a general approach to metal toxicity may be beneficial. The list of heavy metals includes mercury, lead, aluminum, antimony, arsenic, bismuth, cadmium, chromium, cobalt, copper, silver, zinc and tin. Mercury poisoning will be dealt with separately as "Mercury Poisoning (Amalgam Illness)".
Arsenic Useful lab tests include Urinalysis (Oliguria, Hematuria, Hemoglobinuria); Complete Blood Count and Peripheral Smear (Macrocytic Anemia); Tissue Exam (reveals arsenic deposits - urine, nails, hair) and Serum Arsenic levels.
Treatment & Prevention The first step in treating any heavy metal toxicity is to identify the toxic elements and begin the removal process. The easiest screening process is a Hair Analysis. Additional testing involves the use of chelating drugs along with a 24-hour urine collection to determine levels of heavy metals. From here, treatment is based on the individual and will usually involve the use of metal chelating drugs or intravenous EDTA chelation. For many patients, intravenous Vitamin C and replacement mineral infusions are also recommended to support the body through the metal removal process. Once laboratory tests indicate that the heavy metals are undetectable, treatment is considered complete. Often many - if not all - symptoms previously experienced will have resolved, though some may linger, indicating residual damage to organ systems. Therapies can then be targeted to these systems and any specific problems remaining.
Symptoms will often begin to improve within weeks or even days of commencing treatment. Therapy may last from 6 months to 2 years.
Prognosis; Complications Although complete cure is possible, many people suffer the effects of toxicity for extended periods. Some of the damage, for instance to the liver or brain, may not be fully reversible. Others find that their food intolerances will not be completely remedied. Only time will answer that question.
Cadmium may promote skeletal demineralization and increase bone fragility and fracture risk.
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Signs, symptoms & indicators of Heavy Metal Toxicity:
Conditions that suggest Heavy Metal Toxicity:
Risk factors for Heavy Metal Toxicity: |  |  |  | | Addictions | Cigarette Smoke Damage | Tobacco smoking is the most important single source of cadmium exposure in the general population. It has been estimated that about 10% of the cadmium content of a cigarette is inhaled through smoking. The absorption of cadmium from the lungs is much more effective than that from the gut, and as much as 50% of the cadmium inhaled via cigarette smoke may be absorbed.
On average, smokers have 4-5 times higher blood cadmium concentrations and 2-3 times higher kidney cadmium concentrations than non-smokers. Despite the high cadmium content in cigarette smoke, there seems to be little exposure to cadmium from passive smoking. No significant effect on blood cadmium concentrations could be detected in children exposed to environmental tobacco smoke. |
| Supplements and Medications |
(Past) aluminum-based antacid use | Antacids that contain aluminum are potentially dangerous. They should not be freely used for a condition that will respond to an increase in water intake such as stomach ulcers. |
Counter-indicators:
Heavy metal detoxification use | Symptoms - Environment |
Exposure to old building materials
Significant/severe/mild diesel exhaust exposure |
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Heavy Metal Toxicity can lead to:
Heavy Metal Toxicity could instead be:
Recommendations and treatments for Heavy Metal Toxicity: |  |  |  | | Amino Acid / Protein | L-Glutathione
Cysteine / N-Acetyl-Cysteine (NAC) | Cysteine acts as a complexing agent by attaching itself to lead and carrying it out of the body. It is a heavy metal scavenger and liver protector. |
L-Lysine | Lysine has a beneficial effect on lead toxicity. |
| Botanical |
Chlorella | Chlorella can mobilize mercury from inside the brain and from non-neurologic structures (muscles, ligaments, connective tissue and bone). |
Sodium Alginate | Binds with unwanted toxic metals and removes them from the body through the intestinal tract. |
Garlic | Garlic chelates heavy metals such as cadmium, gold, lead and mercury, and acts as a detoxifier. |
| Detoxification |
Heavy Metal Detoxification / Avoidance
Chelation Therapy | EDTA is so effective at removing unwanted minerals and metals from the blood, it has been the standard-FDA-approved-treatment for lead, mercury, aluminum and cadmium poisoning for more than 50 years. |
Attapulgite | Activated Attapulgite (clay) chelates (bonds) with heavy metals throughout the intestinal tract. |
| Diet |
High/Increased Fiber Diet | Sodium alginate as well as other gel-forming fibers have been shown to inhibit heavy metal uptake in the gut. |
Cilantro | Shown in clinical trials and research to mobilize mercury, tin and other toxic metals stored in the brain and spinal cord and move them rapidly out of those tissues. This is a revolutionary discovery and makes Cilantro the first known substance that mobilizes mercury from the CNS (Central Nervous System). |
| Hormone |
Melatonin | Lab Tests/Rule-Outs |
Hair Analysis | Hair analysis is a reasonable and inexpensive first step toward diagnosing heavy metal toxicity. |
| Mineral |
Magnesium Malate | Magnesium malate may be one of the few compounds capable of pulling aluminum from the body over time. |
Selenium | Selenium is able to combine with metals such as cadmium and mercury to reduce their toxicity. |
Zinc | Zinc inhibits the uptake of cadmium and lead by various tissues in the body. Zinc is a well known antagonist to copper. It has been used to treat Wilson's Disease (in which there is an excess of copper). |
| Nutrient |
Alpha Lipoic Acid | Sources of sulfur such as alpha lipoic acid, MSM and garlic are helpful for protection against heavy metals in general and specifically useful in mercury toxicity. Alpha lipoic acid should not be used alone, as it only mobilizes mercury with a weak bond. Without additional chelators present, such as DMPS or DMSA, the mercury may just redistribute elsewhere in the body instead of being removed. |
| Vitamins |
Vitamin C (Ascorbic Acid) | Helps to protect us from heavy metals, particularly lead and arsenic which can poison certain enzyme reactions in the body. |
Bioflavonoids | Bioflavonoids are known for their ability to chelate (bond with and remove) metals from the body. |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Proven definite or direct link |  |  | Strongly counter-indicative |  |  | May do some good |  |  | Likely to help |  |  | Highly recommended |
GLOSSARY
Abdomen (Abdominal) That part of the body between the chest and the hips that contains the stomach, intestines, liver, bladder, pancreas and other organs.
Acute An illness or symptom of sudden onset, which generally has a short duration.
Adrenal (Adrenal Gland, Adrenal Glands, Adrenals) The adrenal glands sit on top of each kidney and consist of an outer cortex and an inner medulla. Of the 50 or so hormones the adrenals make, only cortisone and adrenaline are recognized by most people. Some of these hormones must be produced to preserve life, while others help resist stress. Other hormones from the adrenals control normal energy output (along with the thyroid) and govern the breakdown of stored energy into quick energy sources. The medulla produces epinephrine and norepinephrine, which are specifically designed to help the body deal with stressful situations. The adrenals control the body's potassium/sodium balance, which is vital for energy production. They also produce sex hormones in minute amounts, which is important for later years when the gonads drop or cease their production.
Allergy (Allergies) Hypersensitivity caused by exposure to a particular antigen (allergen), resulting in an increased reactivity to that antigen on subsequent exposure, sometimes with harmful immunologic consequences.
Alzheimer's Disease (Alzheimer's) A progressive disease of the middle-aged and elderly, characterized by loss of function and death of nerve cells in several areas of the brain, leading to loss of mental functions such as memory and learning. Alzheimer's disease is the most common cause of dementia.
Amino Acid (Amino Acids) An organic acid containing nitrogen chemical building blocks that aid in the production of protein in the body. Eight of the twenty-two known amino acids are considered "essential," and must be obtained from dietary sources because the body can not synthesize them.
Anemia (Anaemia, Anemias) A condition resulting from an unusually low number of red blood cells or too little hemoglobin in the red blood cells. The most common type is iron-deficiency anemia in which the red blood cells are reduced in size and number, and hemoglobin levels are low. Clinical symptoms include shortness of breath, lethargy and heart palpitations.
Anorexia Nervosa (Anorexia) An eating disorder characterized by excess control - a morbid fear of obesity leads the sufferer to try and limit or reduce their weight by excessive dieting, exercising, vomiting, purging and use of diuretics. Sufferers are typically more than 15% below the average weight for their height/sex/age and typically have amenorrhea (if female) or low libido (if male). 1-2% of female teenagers are anorexic.
Antacid (Antacids) Neutralizes acid in the stomach, esophagus, or first part of the duodenum.
Antagonist (Antagonists) A chemical substance that interferes with the uptake, assimilation and/or physiological action of another, especially by combining with and blocking its nerve receptor.
Anxiety Apprehension of danger, or dread, accompanied by nervous restlessness, tension, increased heart rate, and shortness of breath unrelated to a clearly identifiable stimulus.
Bioflavonoid (Bioflavonoids, Flavonoid, Flavonoids) Vitamin P. Any of a group of colored flavones (crystalline compounds) found next to the peel in many fruits. Essential for the stability and absorption of ascorbic acid.
Cardiovascular Pertaining to the heart and blood vessels.
Central Nervous System (CNS) A collective term for the brain, spinal cord, their nerves, and the sensory end organs. More broadly, this can even include the neurotransmitting hormones instigated by the CNS that control the chemical nervous system, the endocrine glands.
Chelation Chelation therapy uses EDTA or other supplements that carry heavy metals such as lead, cadmium and arsenic, as well as other foreign substances, from the body. In the process of chelation, a larger protein molecule surrounds or encloses a mineral atom. The purpose of chelation is to increase the flow of blood to the vital organs and tissues of the body by reducing calcium deposits in the arteries and blood vessels.
Chlorella A freshwater, nutritive, single-celled green algae superfood; a regenerative tonic, blood builder, anti-viral, anti-biotic, and anti-carcinogenic that enhances the immune system. It facilitates heavy metals being removed (chelated) from the body.
Chromium Chromium is a mineral that becomes a part of the glucose tolerance factor (GTF). Chromium aids in insulin utilization and blood sugar control. By controlling blood sugar, chromium helps prevent the damage caused by glucose, which is called glycation. Chromium helps maintain normal cholesterol levels and improves high-density lipoprotein levels. Chromium is also important in building muscle and reducing obesity.
Chronic (Chronicity) Usually referring to chronic illness: Illness extending over a long period of time.
Chronic Fatigue Syndrome (CFS, Chronic Fatigue) A disorder of unknown cause that lasts for prolonged periods and causes extreme and debilitating exhaustion as well as a wide range of other symptoms such as fever, headache, muscle ache and joint pain, often resembling flu and other viral infections. Also known as Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS), Chronic Epstein-Barr Virus (CEBV), Myalgic Encephalomyelitis (ME), "Yuppy Flu" and other names, it is frequently misdiagnosed as hypochondria, psychosomatic illness, or depression, because routine medical tests do not detect any problems.
Chronic Renal Failure (Chronic Renal Insufficiency, Kidney Failure, Renal Insufficiency) (CRF) Irreversible, progressive impaired kidney function. The early stage, when the kidneys no longer function properly but do not yet require dialysis, is known as Chronic Renal Insufficiency (CRI). CRI can be difficult to diagnose, as symptoms are not usually apparent until kidney disease has progressed significantly. Common symptoms include a frequent need to urinate and swelling, as well as possible anemia, fatigue, weakness, headaches and loss of appetite. As the disease progresses, other symptoms such as nausea, vomiting, bad breath and itchy skin may develop as toxic metabolites, normally filtered out of the blood by the kidneys, build up to harmful levels. Over time (up to 10 or 20 years), CRF generally progresses from CRI to End-Stage Renal Disease (ESRD, also known as Kidney Failure). Patients with ESRD no longer have kidney function adequate to sustain life and require dialysis or kidney transplantation. Without proper treatment, ESRD is fatal.
Complete Blood Count (CBC) A set of measurements that are generally determined by specially designed machines that analyze the different components of blood in less than a minute. The values generally included are:- White blood cell count (WBC). The number of white blood cells in a volume of blood. Normal range varies slightly between laboratories but is generally between 4,300 and 10,800 cells per cubic millimeter. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 10^9 cells per liter.
- Automated white cell differential. A machine-generated percentage of the different types of white blood cells, usually split into granulocytes, lymphocytes, monocytes, eosinophils, and basophils.
- Red cell count (RBC). The number of red blood cells in a volume of blood. Normal range varies slightly between laboratories but is generally between 4.2 - 5.9 million cells per cubic millimeter. This can also be referred to as the erythrocyte count and can be expressed in international units as 4.2 - 5.9 x 10^12 cells per liter.
- Hemoglobin (Hb). The amount of hemoglobin in a volume of blood. Normal range for hemoglobin is different between the sexes and is approximately 13 - 18 gm/dl for men and 12 - 16 for women (international units 8.1 - 11.2 millimoles/liter for men, 7.4 - 9.9 for women).
- Hematocrit (Hct). The ratio of the volume of red cells to the volume of whole blood. Normal range for hematocrit is different between the sexes and is approximately 45 - 52% for men and 37 - 48% for women.
- Mean cell volume (MCV). The average volume of a red cell. This is a calculated value derived from the hematocrit and red cell count. Normal range is 86 - 98 femtoliters.
- Mean cell hemoglobin (MCH). The average amount of hemoglobin in the average red cell. This is a calculated value derived from the measurement of hemoglobin and the red cell count. Normal range is 27 - 32 picograms.
- Mean cell hemoglobin concentration (MCHC). The average concentration of hemoglobin in a given volume of red cells. This is a calculated volume derived from the hemoglobin measurement and the hematocrit. Normal range is 32 - 36%.
- Red cell distribution width (RDW). A measurement of the variability of red cell size. Higher numbers indicate greater variation in size. Normal range is 11 - 15.
- Platelet count. The number of platelets in a volume blood. Platelets play a vital role in blood clotting. Normal range varies slightly between laboratories but is in the range of 150,000 - 400,000 per cubic millimeter (150 - 400 x 10^9 per liter).
Constipation (Constipated) Difficult, incomplete, or infrequent evacuation of dry, hardened feces from the bowels.
Copper An essential mineral that is a component of several important enzymes in the body and is essential to good health. Copper is found in all body tissues. Copper deficiency leads to a variety of abnormalities, including anemia, skeletal defects, degeneration of the nervous system, reproductive failure, pronounced cardiovascular lesions, elevated blood cholesterol, impaired immunity and defects in the pigmentation and structure of hair. Copper is involved in iron incorporation into hemoglobin. It is also involved with vitamin C in the formation of collagen and the proper functioning in central nervous system. More than a dozen enzymes have been found to contain copper. The best studied are superoxide dismutase (SOD), cytochrome C oxidase, catalase, dopamine hydroxylase, uricase, tryptophan dioxygenase, lecithinase and other monoamine and diamine oxidases.
Cysteine A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. Cysteine is a sulfur-bearing amino acid with antioxidant properties. It is important for keratin synthesis, a protein found in skin, hair and nails and is a component of coenzyme A and glutathione.
Dementia (Senile Dementia) An acquired progressive impairment of intellectual function. Marked compromise exists in at least three of the following mental activity spheres: memory, language, personality, visuospatial skills, and cognition (i.e. abstraction and calculation).
Diarrhea Excessive discharge of contents of bowel.
Edema Abnormal accumulation of fluids within tissues resulting in swelling.
EDTA Ethylene Diamine Tetraacetic Acid. An organic molecule used in chelation therapy.
Enzymes (Enzyme) Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.
Gastrointestinal (GI, GI Tract) Pertaining to the stomach, small and large intestines, colon, rectum, liver, pancreas, and gallbladder.
Gingivitis Inflammation of the fibrous tissues that surround the teeth.
Glucose A sugar that is the simplest form of carbohydrate. It is commonly referred to as blood sugar. The body breaks down carbohydrates in foods into glucose, which serves as the primary fuel for the muscles and the brain.
Glutamine A "conditionally essential" amino acid, glutamine is considered to be a brain fuel. Glutamine has been used therapeutically for alcoholism, mild depression and to reduce the craving for sweets. Glutamine is very important in the functioning of the metabolism and muscle maintenance. Glutamine supplementation can help prevent muscle and other tissue breakdown by providing the body with nitrogen and fuel.
Glutathione A natural sulfur-bearing peptide formed from the linking of three amino acids: glutamic acid, cysteine and glycine. Glutathione acts as an antioxidant and detoxicant and is involved with the selenium-containing enzyme glutathione peroxidase. Glutathione is also involved in amino acid transport across cell membranes and is a powerful free radical scavenger and antioxidant that removes unwanted substances from the body.
Gout A disease characterized by an increased blood uric acid level and sudden onset of episodes of acute arthritis.
Hair Analysis A painless and easy way to test for levels of toxic and essential minerals. A small amount of hair is taken from the nape of the neck and the mineral content of the hair is determined. A computerized analysis reveals the person's condition for the last three months.
Hematuria Blood in the urine.
Hemolytic Anemia Anemia caused by excessive destruction of red blood cells.
Hyperkeratosis Thickening of the skin.
Hypertension High blood pressure. Hypertension increases the risk of heart attack, stroke, and kidney failure because it adds to the workload of the heart, causing it to enlarge and, over time, to weaken; in addition, it may damage the walls of the arteries.
Hypoglycemia A condition characterized by an abnormally low blood glucose level. Severe hypoglycemia is rare and dangerous. It can be caused by medications such as insulin (diabetics are prone to hypoglycemia), severe physical exhaustion, and some illnesses.
Iron An essential mineral. Prevents anemia: as a constituent of hemoglobin, transports oxygen throughout the body. Virtually all of the oxygen used by cells in the life process are brought to the cells by the hemoglobin of red blood cells. Iron is a small but most vital, component of the hemoglobin in 20,000 billion red blood cells, of which 115 million are formed every minute. Heme iron (from meat) is absorbed 10 times more readily than the ferrous or ferric form.
Kidneys (Kidney, Renal) Bean-shaped organs, each about the size of a fist. They are located near the middle of the back, just below the rib cage. The kidneys are sophisticated reprocessing machines, each day handling about 50 gallons of blood to sift out about half a gallon of waste products and extra water. The waste and extra water become urine, which flows to the bladder through tubes called ureters. The actual filtering occurs in tiny units inside the kidneys called nephrons. Every kidney has about a million nephrons. In a nephron, a glomerulus -- which is a tiny blood vessel, or capillary -- intertwines with a tiny urine-collecting tube called a tubule. A complicated chemical exchange takes place, as waste materials and water leave your blood and enter your urinary system. The kidneys recycle chemicals such as sodium, phosphorus, and potassium and thus regulate their levels. Renal: Pertaining to the kidneys.
Lipoic acid (Thioctic Acid) A sulfur-containing coenzyme used in the energy process which is also an extremely powerful antioxidant capable of trapping many different types of free radicals in the body. Has been used therapeutically in the treatment of AIDS and diabetes because of the synergy between alpha-lipoic acid and vitamin E and the interlocking cycles which lead to better optimization of antioxidant nutrients. It is also able of chelating (pulling out) heavy metals such as lead, cadmium and mercury.
Liver (Hepatic) The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.
Lung (Lungs, Pulmonary) Organ of the body, located in the chest cavity which is designed to bring oxygen from the air into the blood stream, while also expelling carbon dioxide and other waste gases out of the body. Pulmonary: Related to the lungs.
Lysine Essential amino acid. Important for growth, tissue repair, and the production of hormones, enzymes and antibodies. Research indicates that lysine may be useful in the treatment of migraine and herpes simplex. Precursor to carnitine in the body.
Magnesium An essential mineral. The chief function of magnesium is to activate certain enzymes, especially those related to carbohydrate metabolism. Another role is to maintain the electrical potential across nerve and muscle membranes. It is essential for proper heartbeat and nerve transmission. Magnesium controls many cellular functions. It is involved in protein formation, DNA production and function and in the storage and release of energy in ATP. Magnesium is closely related to calcium and phosphorus in body function. The average adult body contains approximately one ounce of magnesium. It is the fifth mineral in abundance within the body--behind calcium, phosphorus, potassium and sodium. Although about 70 percent of the body's magnesium is contained in the teeth and bones, its most important functions are carried out by the remainder which is present in the cells of the soft tissues and in the fluid surrounding those cells.
Manganese An essential mineral found in trace amounts in tissues of the body. Adults normally contain an average of 10 to 20mg of manganese in their bodies, most of which is contained in bone, the liver and the kidneys. Manganese is essential to several critical enzymes necessary for energy production, bone and blood formation, nerve function and protein metabolism. It is involved in the metabolism of fats and glucose, the production of cholesterol and it allows the body to use thiamine and Vitamin E. It is also involved in the building and degrading of proteins and nucleic acid, biogenic amine metabolism, which involves the transmitting of nerve impulses.
Metabolism (Metabolic, Metabolize, Metabolizes, Metabolizing) The chemical processes of living cells in which energy is produced in order to replace and repair tissues and maintain a healthy body. Responsible for the production of energy, biosynthesis of important substances, and degradation of various compounds. Also defined as the sum total of changes in an organism in order to achieve a balance (homeostasis): Catabolic burns up, anabolic stores and builds up; the sum of their work is metabolism.
Mineral (Minerals) Plays a vital role in regulating many body functions. They act as catalysts in nerve response, muscle contraction and the metabolism of nutrients in foods. They regulate electrolyte balance and hormonal production, and they strengthen skeletal structures.
Molybdenum An essential trace element. It helps regulate iron stores in the body and is a key component of at least three enzymes: xanthine oxidase, aldehyde oxidase and sulfite oxidase. These enzymes are involved with carbohydrate metabolism, fat oxidation and urine metabolism. The average adult has about 9mg of molybdenum concentrated mostly in the liver, kidney, adrenal glands, bones and skin. Molybdenum deficiencies are associated with esophageal cancer, sexual impotency and tooth decay.
Nausea Symptoms resulting from an inclination to vomit.
Nervous System A system in the body that is comprised of the brain, spinal cord, nerves, ganglia and parts of the receptor organs that receive and interpret stimuli and transmit impulses to effector organs.
Neuritis Nerve inflammation, commonly accompanying other conditions such as tendonitis, bursitis or arthritis. Neuritis is usually accompanied by neuralgia (nerve pain).
Neuropathy A group of symptoms caused by abnormalities in motor or sensory nerves. Symptoms include tingling or numbness in hands or feet followed by gradual, progressive muscular weakness.
Oliguria (Oliguric) The condition of passing small amounts (under 500ml) of urine per day.
Paresthesia A skin sensation, such as burning, prickling, itching, or tingling, with no apparent physical cause.
Parkinson's Disease (Parkinson's) A chronic, slowly-progressing disease of the nervous system characterized clinically by the combination of tremor, rigidity, extreme slowness of movement, and stooped posture. It is characterized pathologically by loss of dopamine in the substantia nigra.
Precursor (Precursors) A biochemical substance, such as an intermediate compound in a chain of enzymatic reactions, from which a more stable or definitive product is formed.
Protein (Proteins) Compounds composed of hydrogen, oxygen, and nitrogen present in the body and in foods that form complex combinations of amino acids. Protein is essential for life and is used for growth and repair. Foods that supply the body with protein include animal products, grains, legumes, and vegetables. Proteins from animal sources contain the essential amino acids. Proteins are changed to amino acids in the body.
Red Blood Cell (Erythrocyte, Erythrocytes, RBC, Red Blood Cells) Any of the hemoglobin-containing cells that carry oxygen to the tissues and are responsible for the red color of blood.
Selenium An essential element involved primarily in enzymes that are antioxidants. Three selenium- containing enzymes are antioxidant peroxidases and a fourth selenium-containing enzyme is involved in thyroid hormone production. The prostate contains a selenium-containing protein and semen contains relatively large amounts of selenium. Clinical studies show that selenium is important in lowering the risk of several types of cancers. In combination with Vitamin E, selenium aids the production of antibodies and helps maintain a healthy heart. It also aids in the function of the pancreas, provides elasticity to tissues and helps cells defend themselves against damage from oxidation.
Septum A membrane wall separating two or more cavities, such as the one between the nasal fossae and those separating the air sacs (alveoli) of the lungs.
Serum The cell-free fluid of the bloodstream. It appears in a test tube after the blood clots and is often used in expressions relating to the levels of certain compounds in the blood stream.
Short-Term Memory (Short Term Memory) Also known as immediate memory or working memory, this is a phase of memory in which a limited amount of information may be held for several seconds to minutes. In general, up to 7 'chunks' of information are stored for about 20 seconds.
Sodium An essential mineral that our bodies regulate and conserve. Excess sodium retention increases the fluid volume (edema) and low sodium leads to less fluid and relative dehydration. The adult body averages a total content of over 100 grams of sodium, of which a surprising one-third is in bone. A small amount of sodium does get into cell interiors, but this represents only about ten percent of the body content. The remaining 57 percent or so of the body sodium content is in the fluid immediately surrounding the cells, where it is the major cation (positive ion). The role of sodium in the extracellular fluid is maintaining osmotic equilibrium (the proper difference in ions dissolved in the fluids inside and outside the cell) and extracellular fluid volume. Sodium is also involved in nerve impulse transmission, muscle tone and nutrient transport. All of these functions are interrelated with potassium.
Stomach A hollow, muscular, J-shaped pouch located in the upper part of the abdomen to the left of the midline. The upper end (fundus) is large and dome-shaped; the area just below the fundus is called the body of the stomach. The fundus and the body are often referred to as the cardiac portion of the stomach. The lower (pyloric) portion curves downward and to the right and includes the antrum and the pylorus. The function of the stomach is to begin digestion by physically breaking down food received from the esophagus. The tissues of the stomach wall are composed of three types of muscle fibers: circular, longitudinal and oblique. These fibers create structural elasticity and contractibility, both of which are needed for digestion. The stomach mucosa contains cells which secrete hydrochloric acid and this in turn activates the other gastric enzymes pepsin and rennin. To protect itself from being destroyed by its own enzymes, the stomach’s mucous lining must constantly regenerate itself.
Thyroid (Thyroid Gland) The thyroid gland is an organ with many veins, anchored around the front of the throat near the voice box. It is essential to normal body growth in infancy and childhood. It absorbs iodine from the diet and releases thyroid hormones - iodine-containing compounds that help govern the rate of the body's metabolism (its total life processes), affecting body temperature, and regulating protein, fat and carbohydrate catabolism in all cells. They keep up growth hormone release, skeletal maturation, and heart rate, force, and output. They promote central nervous system growth, stimulate the making of many enzymes, and are necessary for muscle tone and vigor. To a high degree, metabolism is regulated by the hormone thyroxine, which can be made by the thyroid if enough organic iodine is available. An enlarged thyroid gland that is not cancer is sometimes called goitre.
Ulcer (Ulceration, Ulcers) Lesion on the skin or mucous membrane.
Vanadium Non-essential mineral. It is believed that Vanadium is probably essential to growth and involved in fat metabolism. A vanadium deficiency can increase blood cholesterol and triglyceride levels.
Vertigo The sensation of spinning or whirling; a state in which you or your surroundings seem to whirl dizzily.
Vitamin C (Ascorbic Acid) A water-soluble antioxidant vitamin essential to the body's health. When bound to other nutrients, for example calcium, it would be referred to as "calcium ascorbate". As an antioxidant, it inhibits the formation of nitrosamines (a suspected carcinogen). Vitamin C is important for maintenance of bones, teeth, collagen and blood vessels (capillaries), enhances iron absorption and red blood cell formation, helps in the utilization of carbohydrates and synthesis of fats and proteins, aids in fighting bacterial infections, and interacts with other nutrients. It is present in citrus fruits, tomatoes, berries, potatoes and fresh, green leafy vegetables.
Zinc An essential trace mineral. The functions of zinc are enzymatic. There are over 70 metalloenzymes known to require zinc for their functions. The main biochemicals in which zinc has been found to be necessary include: enzymes and enzymatic function, protein synthesis and carbohydrate metabolism. Zinc is a constituent of insulin and male reproductive fluid. Zinc is necessary for the proper metabolism of alcohol, to get rid of the lactic acid that builds up in working muscles and to transfer it to the lungs. Zinc is involved in the health of the immune system, assists vitamin A utilization and is involved in the formation of bone and teeth.
Last updated: Apr 20, 2009
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