Glutathione

Definition of Glutathione:

A natural sulfur-bearing peptide formed from the linking of three amino acids: glutamic acid, cysteine and glycine.  Glutathione acts as an antioxidant and detoxicant and is involved with the selenium-containing enzyme glutathione peroxidase.  Glutathione is also involved in amino acid transport across cell membranes and is a powerful free radical scavenger and antioxidant that removes unwanted substances from the body.

Topics Related to Glutathione

Alpha Lipoic Acid

...as a treatment
“...It also regenerates other antioxidants like vitamin C, vitamin E and glutathione.  Lipoic acid fights free radical damage in both fatty and watery regions of cells and helps to recycle other antioxidants in what is described as "antioxidant synergism"...”

Alzheimer's Disease

...recommendation Melatonin
“...After exposing nerve cells to inorganic mercury, neurobiologists observed a toxic reaction that reduced cellular levels of the antioxidant glutathione by 30%, triggered the release of plaque-forming β-amyloid peptides, and spurred the hyperphosphorylation of tau-protein – all pivotal mechanisms in the development and progression of...”
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More topics Related to Glutathione

Antioxidant Requirement

...the condition
“...Upon oxidation, these micronutrients need to be regenerated in the biological setting, hence the need for further coupling to other reducing systems such as glutathione/glutathione disulfide, dihydrolipoate/lipoate, or NADPH/NADP+ and NADH/NAD+.  No one antioxidant can achieve this outcome alone...”
...relationship to Parkinson's Disease
“...Numerous studies have shown that Parkinson's disease victims have low levels of natural antioxidants (glutathione and superoxide dismutase) and high levels of iron in the substantia nigra areas of their brains...”

Cabbage Family Vegetables

...as a treatment
“...These agents seem to stimulate the production of protective enzymes such as glutathione that detoxify carcinogens.”

Cancer, General

...recommendation Coffee Enema
“...Dr. Lee Wattenberg, MD was able to show that substances found in coffee – kahweol and cafestol palmitate – promote the activity of a key enzyme system, glutathione S-transferase...”

Cataracts

...the condition
“...The lens, like many other tissues of the body, is dependent on adequate levels and activities of superoxide dismutase (SOD), catalase, glutathione (GSH), and adequate levels of the accessory antioxidants vitamins E and C and selenium, to help prevent free radical damage...”

COPD (Chronic Obstructive Pulmonary Disease)

...recommendation Test Antioxidant Status
“...Deficiencies of glutathione and vitamins E and C were found in patients with COPD...”

Cysteine

...related topic
“...It is important for keratin synthesis, a protein found in skin, hair and nails and is a component of coenzyme A and glutathione.”

Cysteine / N-Acetylcysteine (NAC)

...as a treatment
“...to bind metals such as cadmium and mercury, able to prevent acetaldehyde poisoning (from chronic alcohol or cigarette smoking), and has the ability to increase the activities of both Vitamin B6 and glutathione.  NAC helps the body synthesize glutathione, an important antioxidant...”

Cystine

...as a treatment
“...The N-Acetyl form of Cysteine; helps prevent chemotherapy side-effects and radiation therapy side effects; increases glutathione levels in the lungs, kidneys, liver and bone marrow and has an anti-aging effect on the body...”

Glutamic Acid

...related topic
“Involved in the synthesis of DNA, glutathione and some amino acids...”

Glutamine

...as a treatment
“...Take care not to confuse glutamine with substances that have similar-sounding names, such as glutathione, glutamic acid, gluten, and monosodium glutamate...”

Heavy Metal Toxicity

...recommendation L-Glutathione
“One of the body's normal mechanisms for dealing with heavy metals involves glutathione and normal levels of this protein should thus be ensured...”

Hepatitis

...recommendation L-Glutathione
Glutathione (500mg twice a day) or N-acetyl cysteine (200mg two to three times per day) provide liver cleansing and antioxidant support.”
...recommendation Dandelion
“...It also stimulates the liver's production of Glutathione S-transferase (GST) — an important antioxidant that also helps cleanse the blood.”

Immune System Imbalance (TH2 Dominance)

...recommendation L-Glutathione
Glutathione levels in antigen-presenting cells determine whether Th1 or Th2 response patterns predominate...”

L-Glutathione

...as a treatment
Glutathione is one of the major sulfur-containing compounds in the human body...”
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More topics Related to Glutathione

Liver Detoxification / Support Requirement

...recommendation Coffee Enema
“...It is pivotal in the formation of more glutathione, one of the main conjugation chemicals, enabling toxins to be eliminated via bile into the small intestine...”

Liver Detoxification Phase II Support

...as a treatment
“...These fragments then progress to Phase 2, where they are bound to molecules such as glutathione, glycine and sulfate...”

Liver Detoxification Profile

...as a treatment
“...In addition, glutathione, glutathione peroxidase, superoxide dismutase, plasma cysteine, and plasma sulfate are assessed from fasting blood specimens.”

Macular Degeneration

...recommendation L-Glutathione
“Researchers have found that age-related macular degeneration correlates with low glutathione levels.  When taking into consideration other variables such as smoking, age, cardiovascular disease and multivitamin use, depletion of glutathione by itself was thought to be a major...”

Mercury Toxicity (Amalgam Illness)

...recommendation L-Glutathione
Glutathione can cross the blood-brain barrier; it can remove mercury, cadmium and other toxic metals from the brain.”

Methionine

...as a treatment
“...Methionine is one of only two amino acids that contains a sulfur group, important for methionine's role in the pathway of glutathione "charging"...”

MSM (Methyl Sulfonyl Methane)

...as a treatment
“...It also contributes a sulfur to the body needed to make vitamins such as B1 and the antioxidant amino acid glutathione.  It also helps the liver excrete toxins...”

NAC

...related topic
“...A sulfur compound that is a precursor of glutathione.”

Parkinson's Disease

...recommendation Glutamine
“Raising glutathione levels (a potent antioxidant and detoxifier) will provide a protective effect...”
...recommendation Alpha Lipoic Acid
“Increases glutathione levels.  See the link between Parkinson's Disease and Glutathione.”
...recommendation L-Glutathione
“Since the discovery more than a decade ago that Parkinson's patients suffer from a profound deficiency of the powerful brain antioxidant glutathione, medical researchers have been actively exploring techniques to administer this naturally-occurring chemical...”
...recommendation Cysteine / N-Acetylcysteine (NAC)
“Both cysteine and NAC increase glutathione levels.”
...recommendation Coffee Enema
“Increases glutathione levels in the liver...”

Schisandra Berry

...as a treatment
“...Schisandra lignans appear to protect the liver by activating the enzymes in liver cells that produce glutathione, an important antioxidant substance...”

Selenium

...as a treatment
“...The antioxidant properties of selenium are related to this interaction as well as its active selenoprotein involvement in glutathione metabolism...”

Vitamin E

...as a treatment
“...Vitamin E is able to take free electrons and transfer them to vitamin C, glutathione, or CoQ-10; molecules that are less fat soluble than vitamin E...”
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