Pippali rasayana is a traditional Ayurvedic formulation consisting of Piper longum and Butea monosperma (palash).
Pippali rasayana (PR) has traditionally been used in the treatment of chronic dysentery and worm infestations.
Researchers Agarwal et al investigated the antigiardial and immunostimulatory effects of Pippali rasayana (PR). Agarwals' research team conducted a double-blind, placebo-controlled trial with 50 subjects, all of whom had clinical signs and symptoms of giardiasis, as well as giardia trophozoites and cysts in the stool. Twenty-five subjects received active treatment (1gm PR three times daily), while the others received a placebo. Alter 15 days of treatment, complete disappearance of G. lamblia from the stools was seen in 92% of the PR group and 20% in the placebo group. Diarrhea and the presence of mucous in the stool were also significantly reduced. There was also an improvement in cell-mediated immune status, as assessed by the leukocyte migration inhibition test.
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