Alternative Names: Guaiphenesin.
Guaifenesin's neurological properties first became known in the the lated 1940s, and it still used in veterinary medicine to anesthetize horses being prepped for surgery. When contrasted with other propanediol drugs used for this purpose, guaifenesin causes less destruction of red blood cells and is more soluble in water.
Guaifenesin comes as a regular and extended-release (long-acting) tablet and capsule and liquid to take by mouth. Guaifenesin comes alone and in combination with antihistamines, cough suppressants, and decongestants. It is sold as pills or syrups under many brand names and is also included in many over-the-counter cough and cold remedies.
Guaifenesin is frequently combined with dextromethorphan, an antitussive. Under normal circumstances this combination leads to fewer, but more productive coughs.
Guaifenesin thins the mucus in the air passages and makes it easier to cough up the mucus and clear the airways, allowing you to breathe more easily. It relieves the coughs of colds, bronchitis, and other lung infections.
Guaifenesin was chosen for the experimental guaifenesin protocol in the 1990s as a treatment for fibromyalgia, and proponents of the guaifenesin protocol believe that it cures fybromyalgia by removing excess phosphate from the body. A lesser publicized and thus lesser known fact among fibromyalgia sufferers is that guaifenesin has a skeletal muscle relaxant property, and a form of guaifenesin known as guafenesin carbomate is used for this purpose. This may explain some of the symptomatic relief experienced by fibromyalgia sufferers who take guaifenesin.