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Alternative Names: Nutrasweet, Equal, Spoonful, and Equal-Measure.
The story of Aspartame is interesting in how it was discovered, how it was approved for use, and how it remains on the market. Because of the many different reports of adverse reactions, we do not recommend its use, especially if you have any of the symptoms or conditions it has been linked to.
Reasons For Use Adverse effects reported from short-term and/or long-term use of Aspartame include: Seizures and convulsions, dizziness, tremors, migraines and severe headaches (triggered or caused by chronic intake), memory loss (common toxicity effect), slurring of speech, confusion, numbness or tingling of extremities, chronic fatigue, depression, insomnia, irritability, panic attacks (common aspartame toxicity reaction), marked personality changes, phobias, rapid heart beat (tachycardia - another frequent reaction), asthma, chest pains, hypertension (high blood pressure), nausea or vomiting, diarrhea, abdominal pain, swallowing pain, itching, hives / urticaria, other allergic reactions, blood sugar control problems (e.g. hypoglycemia or hyperglycemia), menstrual cramps and other menstrual problems or changes, impotency and sexual problems, food cravings, weight gain, hair loss / baldness or thinning of hair, burning urination & other urination problems, excessive thirst or excessive hunger, bloating, edema (fluid retention), infection susceptibility, joint pain, brain cancer (in pre-approval studies on animals), death.
Aspartame Disease may mimic symptoms of, or worsen: Fibromyalgia, arthritis, multiple sclerosis (MS), Parkinson's disease, lupus, multiple chemical sensitivities (MCS), diabetes and diabetic Complications, seizures, Alzheimer's disease, birth defects, chronic fatigue syndrome, lymphoma, Lyme's disease, attention deficit disorder (ADD and ADHD), panic disorder, depression and other psychological disorders.
Directions Check all labels very carefully (including vitamins and pharmaceuticals). Look for the word "aspartame" on the label and avoid it. (Also, it is a good idea to avoid "acesulfame-k" or "sunette.") Finally, avoid getting nutrition information from junk food industry PR organizations such as IFIC or organizations that accept large sums of money from the junk and chemical food industry such as the American Dietetic Association.
Products containing Aspartame include instant breakfasts, breath mints, cereals, sugar-free chewing gum, cocoa mixes, coffee beverages, desserts, candies, juice beverages, laxatives, multivitamins, milk drinks, pharmaceuticals, medicines and supplements, shake mixes, soft drinks, tabletop sweeteners, tea beverages, instant teas and coffees, topping mixes, wine coolers, and yogurt amongst other things. The list is almost endless: always read the label.
Expected Outcome It often takes at least sixty days without any aspartame to see a significant improvement in any conditions it may be contributing to. Improvement in health is also often accompanied by weight loss.
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Aspartame (Nutrasweet) Avoidance can help with the following: |  |  |  | | Aging | Alzheimer's Disease | Autoimmune |
Multiple Sclerosis | Circulation |
Mitral Valve Prolapse | Immunity |
Chronic Fatigue / Fibromyalgia Syndrome | Infections |
Lyme Disease
Epstein-Barr virus (EBV)
Post-Polio Syndrome | Mental |
Depression | A double blind study on the effects of aspartame on persons with mood disorders was conducted by Dr. Ralph G. Walton. Since the study wasn't funded/controlled by the makers of aspartame, The Nutrasweet Company refused to sell him the aspartame. Walton was forced to obtain and certify it from an outside source.
The study showed a large increase in serious symptoms for persons taking aspartame. Since some of the symptoms were so serious, the Institutional Review Board had to stop the study. Three of the participants had said that they had been "poisoned" by aspartame. Walton concludes that "individuals with mood disorders are particularly sensitive to this artificial sweetener; its use in this population should be discouraged."
Aware that the experiment could not be repeated because of the danger to the test subjects, Walton was recently quoted as saying, "I know it causes seizures. I'm convinced also that it definitely causes behavioral changes. I'm very angry that this substance is on the market. I personally question the reliability and validity of any studies funded by the Nutrasweet Company."
There are numerous reported cases of low brain serotonin levels, depression and other emotional disorders that have been linked to aspartame and often are relieved by stopping the intake of aspartame. Researchers have pointed out that increasing in phenylalanine levels in the brain, which can and does occur in persons without PKU, leads to a decreased level of the neurotransmitter serotonin, which leads to a variety of emotional disorders. Dr William M. Pardridge of UCLA testified before the US Senate that a youth drinking four 16-ounce bottles of diet soda per day would lead to an enormous increase in phenylalanine levels. |
Panic Attacks
Anxiety | Metabolic |
Aspartame Side-Effects | For those who have chronic health problems that have not responded to other interventions, a trial of avoiding aspartame for several weeks to months may produce noticeable benefits. |
Migraine/Tension Headaches
Meniere's Disease | Musculo-Skeletal |
Carpal Tunnel Syndrome | Nervous System |
Seizure Disorder | In 1984, there were 3 reports about large amounts of Aspartame causing a lowering of the seizure threshold and therefore increasing seizure activity. The Center for Disease Control in Atlanta did a review of this and were unable to find any cause or effect relationship at normal doses. More recently, Aspartame has been found to be unsuitable for some children with generalized absence Epilepsy. A Queen's University study looked at the brain-wave patterns in 10 children and the effects of the artificial sweetener "NutraSweet". A 40% increase in abnormal brain-wave activity associated with absence seizures was found in this study. However, there was no effect on the actual number of seizures. Research on this topic is continuing. |
| Organ Health |
Diabetes Type II | The American Diabetes Association (ADA) is actually recommending this chemical poison to persons with diabetes. According to research conducted by H.J. Roberts, a diabetes specialist, a member of the ADA, and an authority on artificial sweeteners, aspartame:
1) Leads to the precipitation of clinical diabetes. 2) Causes poorer diabetic control in diabetics on insulin or oral drugs. 3) Leads to the aggravation of diabetic complications such as retinopathy, cataracts, neuropathy and gastroparesis. 4) Causes convulsions.
In a statement concerning the use of products containing aspartame by persons with diabetes and hypoglycemia, Roberts says: "Unfortunately, many patients in my practice, and others seen in consultation, developed serious metabolic, neurologic and other complications that could be specifically attributed to using aspartame products. This was evidenced by:
"The loss of diabetic control, the intensification of hypoglycemia, the occurrence of presumed 'insulin reactions' (including convulsions) that proved to be aspartame reactions, and the precipitation, aggravation or simulation of diabetic complications (especially impaired vision and neuropathy) while using these products.
"…dramatic improvement of such features after avoiding aspartame, and the prompt predictable recurrence of these problems when the patient resumed aspartame products, knowingly or inadvertently."
Roberts goes on to say: "I regret the failure of other physicians and the American Diabetes Association (ADA) to sound appropriate warnings to patients and consumers based on these repeated findings which have been described in my corporate-neutral studies and publications." |
| Tumors, Malignant |
Brain Tumor | According to researchers and physicians studying the adverse effects of aspartame, brain tumors can be triggered or worsened by ingesting aspartame.
In 1981 Satya Dubey, an FDA statistician, stated that the brain tumor data on aspartame was so "worrisome" that he could not recommend approval of NutraSweet. In a two-year study conducted by the manufacturer of aspartame, twelve of the 320 rats fed a normal diet and aspartame developed brain tumors while none of the control rats had tumors. Five of the twelve tumors were in rats given a low dose of aspartame. The approval of aspartame was a violation of the Delaney Amendment which was supposed to prevent cancer-causing substances such as methanol (formaldehyde) and DKP from entering our food supply.
The late Dr Adrian Gross, an FDA toxicologist, testified before the US Congress that aspartame was capable of producing brain tumors. This made it illegal for the FDA to set an allowable daily intake at any level. He stated in his testimony that Searle's studies were "to a large extent unreliable" and that "at least one of those studies has established beyond any reasonable doubt that aspartame is capable of inducing brain tumors in experimental animals..." He concluded his testimony by asking, "What is the reason for the apparent refusal by the FDA to invoke for this food additive the so-called Delaney Amendment to the Food, Drug and Cosmetic Act? ... And if the FDA itself elects to violate the law, who is left to protect the health of the public?"
In the mid-1970s it was discovered that the manufacturer of aspartame falsified studies in several ways. One of the techniques used was to cut tumors out of test animals and put them back in the study. Another technique used to falsify the studies was to list animals that had actually died as surviving the study. Thus, the data on brain tumors was likely worse than discussed above. In addition, a former employee of the manufacturer of aspartame, Raymond Schroeder, told the FDA on July 13, 1977 that the particles of DKP were so large that the rats could discriminate between the DKP and their normal diet.
It is interesting to note that the incidence of brain tumors in persons over 65 years of age has increased 67% between the years 1973 and 1990. Brain tumors in all age groups has jumped 10%. The greatest increase has come during the years 1985-1987.
In his book, Aspartame (NutraSweet). Is it Safe?, Roberts gives evidence that aspartame can cause a particularly dangerous form of cancer - primary lymphoma of the brain. |
Non-Hodgkin's Lymphoma | Uro-Genital |
Pregnancy-Related Issues | Dr Diana Dow Edwards, a researcher, was funded by Monsanto to study possible birth defects caused by the ingestion of aspartame. After preliminary data showed damaging information about aspartame, funding for the study was cut off. A separate genetic pediatrician at Emory University has testified that aspartame is causing birth defects.
In the book, While Waiting: A Prenatal Guidebook by George R. Verrilli, M.D. and Anne Marie Mueser, it is stated that aspartame is suspected of causing brain damage in sensitive individuals: a fetus may be at risk for these effects. Some researchers have suggested that high doses of aspartame may be associated with problems ranging from dizziness and subtle brain changes to mental retardation. |
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Aspartame (Nutrasweet) Avoidance can help prevent the following:
KEY |  | May do some good |  |  | Likely to help |  |  | Highly recommended |
GLOSSARY
Abdomen (Abdominal) That part of the body between the chest and the hips that contains the stomach, intestines, liver, bladder, pancreas and other organs.
Alzheimer's Disease (Alzheimer's) A progressive disease of the middle-aged and elderly, characterized by loss of function and death of nerve cells in several areas of the brain, leading to loss of mental functions such as memory and learning. Alzheimer's disease is the most common cause of dementia.
Arthritis (Arthritic) Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. It occurs in various forms, such as bacterial arthritis, osteoarthritis, or rheumatoid arthritis. Osteoarthritis, the most common form, is characterized by a gradual loss of cartilage and often an overgrowth of bone at the joints.
Aspartame A low-calorie sweetener used in a variety of foods and drinks and as a tabletop sweetener. It is about 200 times sweeter than sugar and is commonly known by names such as NutraSweet, Equal, Spoonful or Equal-Measure.
Asthma (Asthmatic) A lung disorder marked by attacks of breathing difficulty, wheezing, coughing, and thick mucus coming from the lungs. The episodes may be triggered by breathing foreign substances (allergens) or pollutants, infection, vigorous exercise, or emotional stress. Extrinsic Asthma is triggered by pollen, chemicals or some other external agent; Intrinsic Asthma is triggered by boggy membranes, congested tissues, or other native causes… even adrenalin stress or exertion.
Cancer Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.
Carpal Tunnel Syndrome A common, painful defect of the wrist and hand. It is caused by pressure on the middle nerve in the carpal tunnel. The syndrome is seen more often in women, especially in pregnant and in menopausal women. Symptoms may result from a blow, swelling, a tumor, rheumatoid arthritis, or a small carpal tunnel that squeezes the nerve. Pain may be infrequent or constant and is often most intense at night.
Cataract (Cataracts) A steadily worsening disease of the eye in which the lens becomes cloudy as a result of the precipitation of proteins. Most cataracts are caused by the functions of the body breaking down. Eye trauma, such as from a puncture wound, may also result in cataracts.
Chronic (Chronicity) Usually referring to chronic illness: Illness extending over a long period of time.
Chronic Fatigue Syndrome (CFS, Chronic Fatigue) A disorder of unknown cause that lasts for prolonged periods and causes extreme and debilitating exhaustion as well as a wide range of other symptoms such as fever, headache, muscle ache and joint pain, often resembling flu and other viral infections. Also known as Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS), Chronic Epstein-Barr Virus (CEBV), Myalgic Encephalomyelitis (ME), "Yuppy Flu" and other names, it is frequently misdiagnosed as hypochondria, psychosomatic illness, or depression, because routine medical tests do not detect any problems.
Cramp (Cramping, Cramps) A sudden, involuntary, painful muscular contraction.
Crave (Craving, Cravings) To have a strong desire for; to feel the need for.
Diabetes Mellitus (Diabetes, Diabetic, Diabetics) A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.
Diarrhea Excessive discharge of contents of bowel.
Edema Abnormal accumulation of fluids within tissues resulting in swelling.
Epilepsy Chronic brain disorder associated with some seizures and, typically, alteration of consciousness.
Epstein Barr Virus (EBV, Epstein-Barr Virus) A virus that causes infectious mononucleosis and that is possibly capable of causing other diseases in immunocompromised hosts.
FDA The (American) Food and Drug Administration. It is the official government agency that is responsible for ensuring that what we put into our bodies - particularly food and drugs - is safe and effective.
Fibromyalgia (FMS) Originally named fibrositis, it is a mysteriously debilitating syndrome that attacks women more often than men. It is not physically damaging to the body in any way, but is characterized by the constant presence of widespread pain that often moves about the body. Fibromyalgia can be so severe that it is often incapacitating.
Hyperglycemia (Hyperglycemic) Elevations of blood glucose, either from the various types of diabetes, excessive sugar intake (short term) or from adrenalin or stimulant causes.
Hypertension High blood pressure. Hypertension increases the risk of heart attack, stroke, and kidney failure because it adds to the workload of the heart, causing it to enlarge and, over time, to weaken; in addition, it may damage the walls of the arteries.
Hypoglycemia A condition characterized by an abnormally low blood glucose level. Severe hypoglycemia is rare and dangerous. It can be caused by medications such as insulin (diabetics are prone to hypoglycemia), severe physical exhaustion, and some illnesses.
Insulin A hormone secreted by the pancreas in response to elevated blood glucose levels. Insulin stimulates the liver, muscles, and fat cells to remove glucose from the blood for use or storage.
Laxative (Laxatives) A substance (food, herb, chemical) that stimulates evacuation of the bowels. Examples include cascara sagrada, senna, castor oil, aloe vera, bisacodyl, phenolphthalein and many others.
Lymphoma (Lymphomas) Any tumor of the lymphatic tissues.
Meniere's Disease (Menieres, Meniere's, Ménière's) An affliction of the middle ear characterized by vertigo, nausea, vomiting, tinnitus and progressive deafness.
Menstruation (Menses, Menstrual, Menstrual Cycle, Menstrual Cycles, Menstrual Flow, Menstrual Phase, Monthly Cycle) The periodic discharge of blood, tissue fluid and mucus from the endometrium (lining of the uterus) that usually lasts from 3 - 5 days. It is caused by a sudden reduction in estrogens and progesterone.
Metabolism (Metabolic, Metabolize, Metabolizes, Metabolizing) The chemical processes of living cells in which energy is produced in order to replace and repair tissues and maintain a healthy body. Responsible for the production of energy, biosynthesis of important substances, and degradation of various compounds. Also defined as the sum total of changes in an organism in order to achieve a balance (homeostasis): Catabolic burns up, anabolic stores and builds up; the sum of their work is metabolism.
Migraine (Migraine Headache, Migraine Headaches, Migraines) Not just a headache, but a disorder affecting the whole body, characterized by clearly defined attacks lasting from about 4 to 72 hours, separated by headache-free periods; progresses through five distinct phases. Prodrome: experienced by about 50% of migraineurs and starting up to 24 hours before the headache - changes in mood, sensory perception, food craving, excessive yawning, or speech or memory problems. Aura: experienced by about 15% and starting within an hour before the headache - disruption of vision (flashing lights, shimmering zigzag lines, blind spot) or sensation (numbness or 'pins and needles' around the lips or hand), or difficulty speaking. Headache: usually pulsating and occurring on one side of the head, it may occur on both sides of the head and alternate from side to side. Muscles in the neck and scalp may be tender; there may be nausea and the desire not to eat, move, see or hear. Resolution: the headache disappears and the body returns to normal. Resolution may occur over several hours during sleep or rest; an intense emotional experience or vomiting may also end the headache. Postdrome: After the headache stops, the sufferer feels drained, fatigued and tired. Muscles ache, emotions are volatile and thinking is slow.
Multiple Chemical Sensitivity (Chemical Hypersensitivity, Environmental Illness, MCS) The diagnostic label of Multiple Chemical Sensitivity (MCS) is being applied increasingly, although definition of the phenomenon is elusive. MCS has become more widely known and increasingly controversial as more patients receive the label. Persons with the label of multiple chemical sensitivity are said to suffer multisystem illnesses as a result of contact with - or proximity to - a spectrum of substances, including airborne agents. These may include both recognized pollutants and other pollutants ordinarily considered harmless. Some doctors believe that MCS is a purely psychological issue. Others, however, counter that the disorder can cause the kinds of problems that keep those who are affected from leading a normal life.
Multiple Sclerosis (MS) Demyelinating disorder of the central nervous system, causing patches of sclerosis (plaques) in the brain and spinal cord, manifested by loss of normal neurological functions, e.g. muscle weakness, loss of vision, and mood alterations.
Nausea Symptoms resulting from an inclination to vomit.
Neuropathy A group of symptoms caused by abnormalities in motor or sensory nerves. Symptoms include tingling or numbness in hands or feet followed by gradual, progressive muscular weakness.
Neurotransmitters (Neurotransmitter) Chemicals in the brain that aid in the transmission of nerve impulses. Various Neurotransmitters are responsible for different functions including controlling mood and muscle movement and inhibiting or causing the sensation of pain.
Ounce (Ounces, oz) Approximately 28 grams.
Panic Attack (Panic Attacks) A brief, irrational episode of fear that is perceived as so real that an individual may be driven to escape from the place or situation where it occurs. The attack is sudden and increases in severity until it leaves, usually within ten minutes. Panic attack symptoms are numerous and involve both mental and physical signs and symptoms. A panic attack can occur in other anxiety states such as agoraphobia and with certain activities and places. It may occur spontaneously without an apparent cause.
Panic Disorder A condition whereby an affected individual has recurrent and unexpected panic attacks and worries a great deal of the time about having another. The individual may also have persistent concern or fear that a panic attack might cause unrelated health problems or a demonstrable change in usual behavior. The symptoms of panic disorder must be present for at least one month to confirm the diagnosis.
Parkinson's Disease (Parkinson's) A chronic, slowly-progressing disease of the nervous system characterized clinically by the combination of tremor, rigidity, extreme slowness of movement, and stooped posture. It is characterized pathologically by loss of dopamine in the substantia nigra.
Phenylalanine Essential amino acid needed for the normal growth of infants and children. It is also needed for normal protein use all through life. Precursor to tyrosine which is used to manufacture certain hormones (epinephrine, norepinephrine, dopa, dopamine) which are important for the transmission of nerve impulses. As neurotransmitters, these substances are believed to influence mood, appetite control and memory. It is found in large amounts in milk, eggs, and other common foods.
Retinopathy An eye disorder that does not cause inflammation but results from changes in the eye (retinal) blood vessels.
Seizure (Seizures) While there are over 40 types of seizure, most are classed as either partial seizures which occur when the excessive electrical activity in the brain is limited to one area or generalized seizures which occur when the excessive electrical activity in the brain encompasses the entire organ. Although there is a wide range of signs, they mainly include such things as falling to the ground; muscle stiffening; jerking and twitching; loss of consciousness; an empty stare; rapid chewing/blinking/breathing. Usually lasting from between a couple of seconds and several minutes, recovery may be immediate or take up to several days.
Serotonin A phenolic amine neurotransmitter (C10H12N2O) that is a powerful vasoconstrictor and is found especially in the brain, blood serum and gastric membranes of mammals. Considered essential for relaxation, sleep, and concentration.
Syndrome A medical condition characterized by a collection of related symptoms (what the patient feels) and signs (what a doctor can observe or measure).
Tachycardia Excessively rapid heart rate.
Tumor (Tumors, Tumour, Tumours) An abnormal growth of tissue resulting from uncontrolled, progressive multiplication of cells and serving no physiological function; a neoplasm. Literally, a swelling; in the past the term has been used in reference to any swelling of the body, no matter what the cause. However, the word is now being used almost exclusively to refer to a neoplastic mass, and the more general usage is being discarded.
Urticaria (Hives) Commonly known as hives, urticaria is one of the most common dermatological conditions seen by allergists. Urticaria is not just an allergic disease, however. It can be caused by metabolic diseases, medications, infectious diseases, autoimmune disease, or physical sensitivity. Traditional allergies to foods or medications as well as viral illness are frequent causes of acute urticaria which usually lasts only a few hours but may last up to 6 weeks. Chronic urticaria (lasting more than 6 weeks) is more complex, given the vast number of potential triggers. Symptoms include sudden onset; initial itching; then swelling of the surface of the skin into red or skin-colored welts (wheals) with clearly defined edges; welts turn white on touching; new welts develop when the skin is scratched; usually disappear within minutes or hours. Welts enlarge, change shape, spread or join together to form large flat raised areas.
Last updated: Oct 08, 2008
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