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Hydrocortisone
  Hydrocortisone
 Recommended for…
 


Alternative Names: Cortisol, Cortef™.

Hydrocortisone is a prescription drug. It is, however, the identical hormone to one of the naturally occurring compounds secreted by the adrenal gland cortex (outside layer) in response to stress or low blood sugar. The correct and safe use of low dose cortisol requires a doctor familiar with its administration.
References & Further Information


The best published source of information is the book, The Safe Uses of Cortisol by William McJeffries, MD. This paper-back book is more expensive than expected, and harder than average to find. If you cannot find a doctor to work with you, it would be better to buy the book rather than give up on the idea of a hydrocortisone trial if it is strongly indicated.





Hydrocortisone can help with the following:
Autoimmune  Ulcerative Colitis
 Ulcerative colitis is both an autoimmune disorder and sensitive to stress. Using hydrocortisol to reduce inflammation followed by physiologic replacement doses when indicated is a reasonable supportive therapeutic strategy.

Hormones

  Low Adrenal Function / Adrenal Insufficiency
 Physiologic replacement doses of oral cortisol can make a dramatic difference in cases of adrenal exhaustion. Because of side-effects induced by larger doses, many doctors are reluctant to use it and many patients are thus deprived of a valuable and needed therapy. Physiologic doses of cortisol (5-25mg per day) are safe. Lab testing can confirm the diagnosis of mild adrenocortical deficiency. A doctor experienced with cortisol use should be consulted; a typical prescription is 5mg four times per day, with an emphasis on early morning use if later doses keep you up at night, or if fewer doses are taken.

Skin-Hair-Nails

Not recommended for:
  Rosacea
 Never apply a topical steroid like cortisone to rosacea unless directed to do so by your doctor for a specific reason. Cortisone treatments can worsen rosacea over the long term and make it even more resistant to treatment.


KEY
May do some good
Highly recommended
May have adverse consequences


GLOSSARY

Adrenal (Adrenal Gland, Adrenal Glands, Adrenals)
The adrenal glands sit on top of each kidney and consist of an outer cortex and an inner medulla. Of the 50 or so hormones the adrenals make, only cortisone and adrenaline are recognized by most people. Some of these hormones must be produced to preserve life, while others help resist stress. Other hormones from the adrenals control normal energy output (along with the thyroid) and govern the breakdown of stored energy into quick energy sources. The medulla produces epinephrine and norepinephrine, which are specifically designed to help the body deal with stressful situations. The adrenals control the body's potassium/sodium balance, which is vital for energy production. They also produce sex hormones in minute amounts, which is important for later years when the gonads drop or cease their production.

Adrenal Insufficiency (Adrenal Exhaustion, Low Adrenal Function)
A condition in which the adrenal gland is compromised in its production of epinephrine, norepinephrine, cortisol, corticosterone or aldosterone. Symptoms include primarily fatigue, weakness, decreased appetite with ensuing weight loss, as well as nausea, vomiting, abdominal pain, diarrhea or constipation, or increased pigmentation of the skin. Cortical insufficiency (low or no corticosteroids) produces a more serious condition called Addison’s Disease, characterized by extreme weakness, low blood pressure, pigmentation of the skin, shock or even death.

Autoimmune Disease (Autoimmune, Autoimmunity)
One of a large group of diseases in which the immune system turns against the body's own cells, tissues and organs, leading to chronic and often deadly conditions. Examples include multiple sclerosis, rheumatoid arthritis, systemic lupus, Bright's disease and diabetes.

Cortisol
A hormone. Its most important function is to help the body respond to stress. It also helps regulate your body's use of protein, carbohydrates and fat; it helps maintain blood pressure and cardiovascular function; it stems inflammation.

Hormones (Hormone)
Chemical substances secreted by a variety of body organs that are carried by the bloodstream and usually influence cells some distance from the source of production. Hormones signal certain enzymes to perform their functions and, in this way, regulate such body functions as blood sugar levels, insulin levels, the menstrual cycle, and growth. These can be prescription, over-the-counter, synthetic or natural agents. Examples include adrenal hormones such as corticosteroids and aldosterone; glucagon, growth hormone, insulin, testosterone, estrogens, progestins, progesterone, DHEA, melatonin, and thyroid hormones such as thyroxine and calcitonin.

Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.

Steroid (Steroids)
Any of a large number of hormonal substances with a similar basic chemical structure containing a 17-carbon 14-ring system and including the sterols and various hormones and glycosides.

Topical
Most commonly 'topical application': Administration to the skin.

Ulcerative Colitis (Colitis Ulcerosa)
Ulceration of the colon and rectum, usually long-term and characterized by rectal bleeding or blood in the stool, frequent urgent diarrhea/bowel movements each day, abdominal pain.




Last updated: Oct 08, 2008


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