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Malic Acid
 


Malic acid, also known as hydroxysuccinic acid, is a naturally occurring acid found in apples as well as other fruits. Malic acid has gained its way into the list of supplemental ingredients as a support for the condition known as fibromyalgia (FM). It has been postulated that FM is caused by local hypoxic (low oxygen) conditions within muscle fibers. The low oxygen levels require ATP to be made in an anaerobic environment, a set of reactions in which malate (the anion of malic acid) and magnesium are both required. Malic acid, along with magnesium have been successful in some preliminary trials in patients with FM. Dosages of Malic acid ranged from 1200-2400mg per day.





GLOSSARY

Adenosine Triphosphate (ATP)
A compound consisting of the nucleotide adenosine attached through its ribose group to three phosphoric acid molecules. It serves to store energy in muscles which is released when it is hydrolyzed to adenosine diphosphate.

Anaerobic (Anaerobically)
Of, relating to, or being activity in which the body incurs an oxygen debt (for example weight training or resistive exercises) and does not immediately burn off a lot of calories and fat.

Fibromyalgia (FMS)
Originally named fibrositis, it is a mysteriously debilitating syndrome that attacks women more often than men. It is not physically damaging to the body in any way, but is characterized by the constant presence of widespread pain that often moves about the body. Fibromyalgia can be so severe that it is often incapacitating.

Magnesium
An essential mineral. The chief function of magnesium is to activate certain enzymes, especially those related to carbohydrate metabolism. Another role is to maintain the electrical potential across nerve and muscle membranes. It is essential for proper heartbeat and nerve transmission. Magnesium controls many cellular functions. It is involved in protein formation, DNA production and function and in the storage and release of energy in ATP. Magnesium is closely related to calcium and phosphorus in body function. The average adult body contains approximately one ounce of magnesium. It is the fifth mineral in abundance within the body--behind calcium, phosphorus, potassium and sodium. Although about 70 percent of the body's magnesium is contained in the teeth and bones, its most important functions are carried out by the remainder which is present in the cells of the soft tissues and in the fluid surrounding those cells.

Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.




Last updated: Oct 08, 2008


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