 Vitamin Niacinamide can help with the following: | |  | | | Allergy |  Allergic Rhinitis / Hay Fever |
Autoimmune |
Diabetes Type I | Niacinamide improves ATP mitochondrial production in the face of diabetogenic chemicals and thus allows Islet cells to stay alive. The Type I honeymoon period can just be extended 12-18 months and insulin requirements may be less. |
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Infections |
 Sinusitis |
Mental |
Anxiety| | The textbook description of anxiety neurosis exactly matches the symptoms of vitamin B3 (niacin) deficiency: hyperactivity, depression, fatigue, apprehension, headache, and insomnia. It has been shown in animals to work in the brain in ways similar to drugs such as benzodiazepines (Valium-type drugs) that are used to treat anxiety. One study found that niacinamide (not niacin) could help people get through withdrawal from benzodiazepines, which is a common problem. A reasonable amount of niacinamide to take for anxiety, according to some doctors, is up to 500mg four times per day.
Niacinamide locks onto the same receptor sites in the brain as do tranquilizers such as Valium, and is a natural tranquilizer. The manufacturer of valium is also the worlds largest manufacturer of niacinamide. [Nature 278: pp.563-5,1979] |
Poor Sense of Humor| | Early signs of vitamin B3 (Niacin) depletion include the loss of a sense of humor. |
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Metabolic |
Hypoglycemia
Migraine/Tension Headaches |
Musculo-Skeletal |
Osteoarthritis| | Results may be seen in 3-4 weeks with a plateau of improvement reached at 12 weeks. The dose may be lowered at this time but if discontinued, the symptoms will come back. Intake of 500mg 3-6 times daily has commonly been recommended. Sustained release forms require less frequent dosing. [Inflamm Res 1996;45: pp.330-4] |
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Nutrients |
Vitamin B3 Requirement |
Organ Health |
Diabetes Type II| | Niacinamide improves ATP mitochondrial production in the face of diabetogenic chemicals and thus allows insulin-producing cells of the pancreas to stay alive longer. In one trial, newly diagnosed patients were given niacinamide at 25mg per kg of body weight. This restored the insulin-producing cells of the pancreas in some, slowed the cellular destruction in others and left a number no longer diabetic. Use in diabetic patients should always be monitored by a physician as insulin requirements may change. |
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Skin-Hair-Nails |
Adult Acne| | Though harder to find, a topically-applied 4% solution of niacinamide compared very favorably to Clindamycin in one trial. Oral niacinamide is unlikely to be of benefit. |
Hives| | Should be taken in combination with Tyrosine. See Hives/Tyrosine note. |
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Vitamin Niacinamide can help prevent the following:
KEY | | May do some good | | | Likely to help |
GLOSSARY
Adenosine Triphosphate (ATP)
A compound consisting of the nucleotide adenosine attached through its ribose group to three phosphoric acid molecules. It serves to store energy in muscles which is released when it is hydrolyzed to adenosine diphosphate.
Anxiety
Apprehension of danger, or dread, accompanied by nervous restlessness, tension, increased heart rate, and shortness of breath unrelated to a clearly identifiable stimulus.
Diabetes Mellitus (Diabetes, Diabetic, Diabetics)
A disease with increased blood glucose levels due to lack or ineffectiveness of insulin. Diabetes is found in two forms; insulin-dependent diabetes (juvenile-onset) and non-insulin-dependent (adult-onset). Symptoms include increased thirst; increased urination; weight loss in spite of increased appetite; fatigue; nausea; vomiting; frequent infections including bladder, vaginal, and skin; blurred vision; impotence in men; bad breath; cessation of menses; diminished skin fullness. Other symptoms include bleeding gums; ear noise/buzzing; diarrhea; depression; confusion.
Enzymes (Enzyme)
Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.
Insulin
A hormone secreted by the pancreas in response to elevated blood glucose levels. Insulin stimulates the liver, muscles, and fat cells to remove glucose from the blood for use or storage.
Kilogram (kg, kgs, Kilogramme, Kilogrammes, Kilograms)
1000 grams, 2.2lbs.
Lipid (Lipids)
Fat-soluble substances derived from animal or vegetable cells by nonpolar solvents (e.g. ether); the term can include the following types of materials: fatty acids, glycerides, phospholipids, alcohols and waxes.
Liver (Hepatic)
The largest and one of the most complex organs of the body, the liver is responsible for much of the metabolism of fats, proteins and carbohydrates. It is the site of much of the body's detoxification. It is connected very closely with digestion and the regulation of blood sugar, among many other functions. Found behind the ribs on the right side of the abdomen, it has many important functions such as removing harmful material from the blood, making enzymes and bile that help digest food, and converting food into substances needed for life and growth. Hepatic: Pertaining to the liver.
Milligram (mg, Milligrams)
0.001 or a thousandth of a gram.
Nausea
Symptoms resulting from an inclination to vomit.
Niacin (B3, B-3, Niacinamide, Vitamin B3)
A coenzyme B-complex vitamin that assists in the breakdown of carbohydrates, fats and proteins. Essential for the health of the skin, nerves, tongue and digestive system. It is found in every cell of the body and is necessary for energy production. Niacin is also needed for DNA formation.
Pancreas (Pancreatic)
Opposite the liver and behind the stomach, the pancreas has two main functions - to manufacture various enzymes for digestion, and to release hormones to help control the body's use of carbohydrates. It releases insulin to help each cell absorb glucose to burn as energy. In this way, insulin controls the amount of sugar (glucose) in the blood. Proper pancreatic function is very important: too much, too little, or no insulin production can be life-threatening. Some of the chemicals released by the pancreas are not hormones, but stimulate other glands to make hormones. Once again, balance is necessary. Nutritional requirements for the pancreas are many. Research indicates that chromium vitamins C, E, B-complex, calcium, magnesium and potassium are especially important.
Sinusitis
Inflammation of the sinuses, with causes ranging from dust to hay fever. Obstinate cases can be caused by chronic sinus infections or the continued exposure to allergens from food, pets or environmental irritants.
Tyrosine
A nonessential amino acid but may be essential for individuals with certain diseases or nutritional concerns. May be important for neurotransmitter synthesis and mood regulation. May be useful for depression, allergies and addictive states.
Urticaria (Hives)
Commonly known as hives, urticaria is one of the most common dermatological conditions seen by allergists. Urticaria is not just an allergic disease, however. It can be caused by metabolic diseases, medications, infectious diseases, autoimmune disease, or physical sensitivity. Traditional allergies to foods or medications as well as viral illness are frequent causes of acute urticaria which usually lasts only a few hours but may last up to 6 weeks. Chronic urticaria (lasting more than 6 weeks) is more complex, given the vast number of potential triggers. Symptoms include sudden onset; initial itching; then swelling of the surface of the skin into red or skin-colored welts (wheals) with clearly defined edges; welts turn white on touching; new welts develop when the skin is scratched; usually disappear within minutes or hours. Welts enlarge, change shape, spread or join together to form large flat raised areas.
Vitamin B6 (B6, B-6)
Influences many body functions including regulating blood glucose levels, manufacturing hemoglobin and aiding the utilization of protein, carbohydrates and fats. It also aids in the function of the nervous system.
Last updated: Jun 15, 2008
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