Several issues are raised when levels of serum uric acid (a natural antioxidant) are low. It has previously been thought that lower uric acid levels were not associated with any problems but that may not be the case. Low uric acid levels may be associated with a molybdenum deficiency, copper toxicity, and a worsening of multiple sclerosis.
Causes and Development
Low dietary zinc
intakes cause lower uric acid
levels. This effect can be even more pronounced in women taking oral contraceptive medication. [Hess FM et al, 1 December 1977. "Effect of low zinc intake and oral contraceptive agents on nitrogen utilization and clinical findings in young women". The Journal of Nutrition 107 (12): pp2219-27.
Drug(s) indicated for prevention of hyperphosphataemia in patients with chronic renal failure
, can significantly reduce serum uric acid.
Treatment and Prevention
Correcting low or deficient zinc
levels can help elevate serum uric acid
. Inosine can be used to elevate uric acid levels.