Hypogonadism, Male

Hypogonadism, Male: Overview

Male hypogonadism with a deficiency of testosterone is a relatively common disorder in clinical practice and has significant effects on the fertility, sexual function, and general health of affected men. Hypogonadism can occur for a number of reasons, some relatively common and others rare.  Certain men have hypogonadism from birth while others may develop this condition later in life.  Types of hypogonadism include:
  • Primary hypogonadism (testicular failure) – Low serum testosterone levels with gonadotropins (FSH, LH) above the normal range.  Klinefelters, surgical removal, bilateral mumps related orchitis, toxic damage by alcohol, heavy metals or chemotherapy.
  • Secondary (gonadotropin) hypogonadism – Caused by a pituitary failure or pituitary-hypothalamic injury from tumors, trauma, or radiation; characterized by low serum testosterone levels, but with gonadotropins in the normal or low range

Signs and Symptoms

  • Impotence
  • Decreased sexual desire
  • Fatigue and loss of energy
  • Mood depression
  • Regression of secondary sexual characteristics (growth and maturation of prostate, seminal vesicles, penis, and scrotum; the development of male hair distribution, including facial, pubic, chest, axillary hair; laryngeal enlargement; vocal chord thickening; alterations in body musculature; fat distribution)
  • Osteoporosis.

Treatment and Prevention

In men with clinical symptoms of primary or secondary hypogonadism, the deficiency of testosterone can be treated effectively with currently available preparations.

Male Hypogonadism

Information On This Page

Signs, symptoms & indicators of Hypogonadism, Male:

Symptoms - Muscular

Conditions that suggest Hypogonadism, Male:

Hormones

Mental

Reproductive

Risk factors for Hypogonadism, Male:

Hormones

KEY

Weak or unproven link: may be a sign or symptom of; may suggest
Weak or unproven link:
may be a sign or symptom of; may suggest
Strong or generally accepted link: often suggests
Strong or generally accepted link:
often suggests
Definite or direct link: increases risk of
Definite or direct link:
increases risk of