Chronic Eosinophilic Leukemia
(CEL)

Chronic Eosinophilic Leukemia (CEL): Overview

Chronic eosinophilic leukemia (CEL) is a highly rare disease in which too many eosinophils (a type of white blood cell) are found in the bone marrow, blood, and other tissues.

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Causes and Development

CEL is generally caused by overactivation of the oncogene PDGFRA through a chromosome translocation event.

Prognosis; Complications

CEL is extremely manageable with the use of Gleevec, which suppresses the oncogenic effects of PDGFRA.

CEL may stay the same for many years, or it may progress quickly to acute leukemia.

On This Page

CEL Leukemia:

Chronic Eosinophilic Leukemia (CEL) suggests the following may be present:

Circulation

Tumors, Malignant

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suggests