Our Question About
Your Urine MMA Level



In the 'Lab Values - Nutrients' section of our in-depth questionnaire we ask the following question about your urine MMA level:
 
Urine MMA. Normal levels are below 3.8ug of MMA per mg of creatinine (below 3.6umol MMA per mmol of creatinine); Elevated levels are anything above this.
# Your answer ...indicates/suggests
1 "Don't know"
2 "Normal" Risk factor: Normal urine MMA levels
3 "Elevated" Risk factor: Elevated urine MMA levels




Your answer to the question above will affect the likelihoods of the conditions below.  Any answers in green reduce the likelihood of the condition.
 
Answers # Condition Comment
    3     Vitamin B12 Requirement The UMMA test is a functional assay. UMMA reflects cobalamin (Vitamin B12) activity at the tissue/cellular level since MMA levels are directly related to a B12-dependent metabolic pathway. The conversion of MMA to succinic acid requires vitamin B12. The metabolic pathway is: MMA --> (coenzyme B12 ) --> succinic acid.

Vitamin B12 deficiency impedes this pathway and causes MMA levels to increase. Thus, as water builds up behind a dam, high UMMA levels indicate a vitamin B12 deficiency.
  2       Vitamin B12 Requirement --






Last updated: Dec 30, 2011