In the 'Lab Values - Nutrients' section of our in-depth questionnaire we ask the following question about your urine MMA level:
Urine MMA. Normal levels are below 3.8ug of MMA per mg of creatinine (below 3.6umol MMA per mmol of creatinine); Elevated levels are anything above this.
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Your answer
...indicates/suggests
1
"Don't know"
2
"Normal"
Risk factor: Normal urine MMA levels
3
"Elevated"
Risk factor: Elevated urine MMA levels
Your answer to the question above will affect the likelihoods of the conditions below.
Any answers in greenreduce the likelihood of the condition.
The UMMA test is a functional assay. UMMA reflects cobalamin (Vitamin B12) activity at the tissue/cellular level since MMA levels are directly related to a B12-dependent metabolic pathway. The conversion of MMA to succinic acid requires vitamin B12. The metabolic pathway is: MMA --> (coenzyme B12 ) --> succinic acid.
Vitamin B12 deficiency impedes this pathway and causes MMA levels to increase. Thus, as water builds up behind a dam, high UMMA levels indicate a vitamin B12 deficiency.