In the 'Supplements And Medications' section of our in-depth questionnaire we ask the following question about progestin use:
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Have you used progestins (such as Provera, Agest or Depo-Provera/DMPA)? Prempro contains a progestin also.
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Your answer |
...indicates |
...and suggests |
| 1. |
"No / don't know" |
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| 2. |
"For under 1 year, but not any more" |
Past progestin use |
A risk factor |
| 3. |
"For 1 or more years, but not any more" |
Past progestin use |
A risk factor |
| 4. |
"Current use for under 1 year" |
Progestin use |
A risk factor |
| 5. |
"Current use for 1 or more years" |
Progestin use |
A risk factor |
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Your answer will affect the likelihoods of the conditions below.
Any answers in green reduce the likelihood of the condition.
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| Answers |
Condition |
Comment |
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5 |
Amenorrhea |
(Women only) Injected progestins have been the standard form of injected contraceptive - and are very effective - but they can have severe effects on the menstrual cycle. Like other progestin contraceptives, Depo-Provera prevents pregnancy by halting ovulation, thickening the cervical mucus, and stopping the implantation of fertilized eggs in the uterine lining. |
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Phlebitis / Thrombophlebitis |
The use of progestins (synthetic progesterones, but not natural progesterone) will increase the likelihood of deep vein thrombophlebitis by 3 to 4 times. |
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GLOSSARY
Menstruation (Menses, Menstrual, Menstrual Cycle, Menstrual Cycles, Menstrual Flow, Menstrual Phase, Monthly Cycle)
The periodic discharge of blood, tissue fluid and mucus from the endometrium (lining of the uterus) that usually lasts from 3 - 5 days. It is caused by a sudden reduction in estrogens and progesterone.
Mucus (Mucous)
The viscous, slippery substance that consists chiefly of mucin, water, cells, and inorganic salts and is secreted as a protective lubricant coating by cells and glands of the mucous membranes.
Progesterone
This is the hormone secreted after ovulation by the corpus luteum. It is a steroid (similar to a cholesterol), enters receptive cells to stimulate their growth, and acts as an anabolic agent. Estrogen should be viewed as the primary coat underneath all the cycles during a woman's reproductive years, with progesterone, its antagonist, surging for ten or twelve days in ovulatory months. Most of the actions of progesterone cannot occur without estrogen having previously induced the growth of progesterone-receptive binding sites.
Thrombophlebitis
Venous inflammation with formation of clots. It can occur without any symptoms until the clot reaches the lungs. However, in about half of cases, there are warning symptoms including swelling, pain and warmth in the entire calf, ankle, foot, or thigh (depending on where the involved vein is located).
Uterus (Uterine)
The part of the female reproductive system specialized to allow the implantation, growth and nourishment of a fetus during pregnancy.
Last updated: Feb 28, 2008
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