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Glossary: Histamine
 


Definition
A chemical in the body tissues, produced by the breakdown of histidine. It is released in allergic reactions and causes widening of capillaries, decreased blood pressure, increased release of gastric juice, fluid leakage forming itchy skin and hives, and tightening of smooth muscles of the bronchial tube and uterus. Histamine is the chemical that drives the initial acute allergic reaction, causing itching, swelling and congestion.

Topics Related To Histamine
Addictions / Addictive TendenciesRelationship to Histadelia (Histamine High)
"Nutritional treatment for drug and alcohol users will depend on the results of a test for blood histamine levels..."

Allergic Rhinitis / Hay Fever

Recommendation Vitamin B5 (Pantothenic Acid)
"...108] Szorady conducted allergy skin tests on 24 children injecting them with histamine..."

Allergy to Foods (Hidden)

Our Question about epigastric pain
"...Sometimes mast cells are involved in allergic reactions and release chemicals such as histamine..."

Asthma

Recommendation Bioflavonoids
"...It has been shown to inhibit histamine release from mast cells and basophils when stimulated by antigens (triggers)..."

Basophil

Related Topic
"...They release chemicals such as histamine and play a role in the inflammatory response to infection..."

Bioflavonoids

As A Treatment
"...It appears to stabilize the membranes of the mast cells that release histamine..."

Cataracts

Recommendation Carnosine
"...L-Carnosine releases the toxic compound, histamine, which can severely promote oxidation reactions..."

Cluster Headaches

The Condition
"Cluster headache (CH), also known as histamine headache, is a specific vascular headache syndrome and one of the most severe forms of headache..."

Feverfew

As A Treatment
"...Parthenolide is thought to work as an anti-inflammatory agent via inhibition of inflammatory prostaglandins, reduction of histamine production and eventually reducing the activity of inflammatory cells..."

Heartburn / GERD / Acid Reflux

Recommendation MSM (Methyl Sulfonyl Methane)
"Doctors using MSM agree that patients who have used antacids and histamine receptor antagonists to control hyperacidity can employ MSM with good results..."

Histadelia (Histamine High)

The Condition
"Histadelia, more common in males, is characterized by elevated blood levels of histamine..."

Recommendation against Folic Acid
"Histadelics should avoid supplemental folic acid as it can produce excess histamine..."

Recommendation Methionine
"Methionine supplements lower blood levels of histamine by increasing histamine breakdown..."

Histamine Therapy

As A Treatment
"...The strategy of administering small doses of histamine is meant to balance out the parts of the immune system that stimulates allergies or auto-immunity, and the parts of the immune system that keep the allergic or autoimmune reactions under..."

Histapenia (Histamine Low)

The Condition
"...Since copper is a brain stimulant and destroys histamine, the elevated serum (and presumably brain) copper level probably accounts for many symptoms, including the low blood histamine level..."

Our Question about childhood hyperactivity
"Low histamine children are hyperactive while often healthy in other respects..."

Relationship to Schizophrenia
"It has been found that 50% of patients classified as "schizophrenic" have low histamine levels in the blood and it rises to normal as they improve..."

Recommendation Zinc
"...Zinc and manganese allow for the normal storage of histamine in both basophils and the brain..."

Recommendation Folic Acid
"The rationale underlying this treatment is that folic acid in conjunction with vitamin B12 injections raises the blood histamine while lowering the degree of symptoms..."

Hives

The Condition
"...The reaction involves the release of histamine from either mast cells or basophils causing an IgE (immediate type) mediated antibody response..."

Recommendation Bioflavonoids
"The flavonoid quercetin inhibits the manufacture and release of histamine and other allergic compounds involved in allergies..."

Recommendation Conventional Drug Use
"...This is because in people with hives, histamine is being released by mast cells in the tissues which in turn initiaties the irritation and accumulations of fluid..."

Recommendation Vitamin C (Ascorbic Acid)
"High doses of vitamin C, such as mineral ascorbates, can help those with hives by lowering histamine levels..."

Indoor Allergies

Recommendation Vitamin B5 (Pantothenic Acid)
"...Szorady conducted allergy skin tests on 24 children injecting them with histamine to induce symptoms..."

Recommendation Bioflavonoids
"May reduce IgE formation, inhibit the release of histamine, and reduce or eliminate allergy symptoms..."

Mast Cells

Related Topic
"...They bind IgE, supply the histamine and heparin response that gives you a healing inflammation, and cause allergies..."

Meniere's Disease

Recommendation Histamine Therapy
"Histamine diphosphate therapy at 2..."

Methionine

As A Treatment
"...Methionine prevents fat build-up by assisting in the breakdown of fats; it detoxifies the digestive system; it is a powerful antioxidant; it reduces histamine levels; helps women excrete estrogen; helps to detoxify the liver..."

Multiple Sclerosis

Recommendation Histamine Therapy
"..., reports that after six weeks of treatment with histamine in 19 individuals with multiple sclerosis..."

Polycystic Ovary Syndrome (PCOS)

The Condition
"...Both cimetidine and cyproheptadine (a serotonin and histamine antagonist) have weak anti-androgenic effects..."

Pyroluria

The Condition
"...Pyroluria may occur along with other imbalances as seen in some subtypes of schizophrenia such as histapenia (low histamine), histadelia (high histamine), high copper levels or cerebral allergies..."

Relationship to Schizophrenia
"...(At least 10% of these also have histamine problems..."

Stinging Nettle

As A Treatment
"...These small sac-like structures contain amines such as histamine, as well as folic acid..."

Test for Inhalant Allergies

As A Treatment
"...Upon encountering an allergen, IgE activates special cells called mast cells, which in turn release chemicals called mediators -- such as histamine, the chemical that causes redness and swelling..."

Test Histamine Levels

As A Treatment
"Histamine is a chemical (neuro-transmitter) responsible for numerous symptoms of allergic reaction..."

Vitamin B3 (Niacin)

As A Treatment
"...orally as nicotinic acid, can produce redness, warmth, and itching over areas of the skin; this "niacin flush" usually occurs when doses of 50mg or more are taken and is a result of the release of histamine by the cells, which causes vasodilation..."





Last updated: Nov 14, 2009


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