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Glossary: Folic Acid
 


Definition
A B-complex vitamin that functions along with vitamin B-12 and vitamin C in the utilization of proteins. It has an essential role in the formation of heme (the iron containing protein in hemoglobin necessary for the formation of red blood cells) and DNA. Folic acid is essential during pregnancy to prevent neural tubular defects in the developing fetus.

Topics Related To Folic Acid
A Vegetarian DietThe Condition
"...Most doctors also recommend that pregnant women supplement their diet with iron and folic acid, although vegetarians normally consume more folic acid than meat-eaters..."

Alcohol-related Problems

Relationship to Increased Folic Acid Requirement
"Alcohol interferes with the metabolism and absorption of folic acid..."

Alfalfa

As A Treatment
"...Powdered Alfalfa contains vitamins A, B-1, B-6, B-12, C, E, & K-1, niacin, pantothenic acid, biotin, folic acid and many essential and nonessential amino acids..."

Alzheimer's Disease

Recommendation Vitamin B-Complex
"Optimize your B-complex status, especially folic acid and B12..."

Atherosclerosis

Recommendation Folic Acid
"For improved homocysteine metabolism, folic acid (800mcg per day), B6 (50mg per day), B12 (400mg per day), betaine (200 to 1,000mg per day are recommended..."

Biotin

As A Treatment
"...Biotin also assists in the synthesis and utilization of Vitamin B-9 (Folic Acid), Vitamin B-12 (Cobalamin), Vitamin B-5 (Pantothenic Acid), and protein..."

Birth Control Pill Issues

The Condition
"...Causes & Development Nutrients that can be reduced by the use of Oral Contraceptives (OC): Folic Acid (Folate)..."

Bruising Susceptibility

The Condition
"...Possible causes of bruising include ... Nutritional deficiencies, such as deficiency in vitamins C, K, B12, or folic acid..."

Cervical Dysplasia

Recommendation Folic Acid
"Folic Acid in high doses of 10 to 50mg per day have been used successfully to return Pap smears to normal..."

Chemotherapy Side-Effects

Relationship to Megaloblastic Anemia / Pernicious Anemia
"Some chemotherapy agents are known inhibitors of folic acid enzymes and as such can induce a megaloblastic anemia..."

Chronic / Hidden Infection

Relationship to Increased Folic Acid Requirement
"Folic acid deficiency anemia can lead to increased susceptibility to infection..."

Chronic Renal Insufficiency

Recommendation Folic Acid
"...Taking 5mg of folic acid daily can significantly lower these homocysteine levels..."

Colon Cancer

Recommendation Folic Acid
"Long-term use of a multivitamin containing 400mcg of folic acid, found mostly in leafy green vegetables, beans and nuts, may reduce the risk of colon cancer in women by as much as 75%..."

Coronary Disease / Heart Attack

Recommendation Folic Acid
"...A study found that people with a dietary intake of at least 300mcg per day of folic acid reduced their risk of stroke and heart disease by 20% and 13% respectively, compared with those who consumed less than 136mcg of folic acid per day..."

Recommendation Vitamin B-Complex
"105 male and female subjects with coronary artery disease who received folic acid (1mg/day), vitamin B12 (400mcg/day) and vitamin B6 (10mg/day) experienced a significant reduction in reblockage after angioplasty over those who did not take the vitamins..."

Depression

Relationship to Increased Folic Acid Requirement
"There is substantial scientific evidence linking folic acid deficiency to depression..."

Elevated Homocysteine Levels

The Condition
"...As a major consequence of folic acid deficiency -- a particular problem with the elderly -- elevated homocysteine impairs DNA repair..."

Recommendation Folic Acid
"A deficiency of vitamin B12 is associated with elevated homocysteine levels and folic acid is essential for its proper metabolism..."

Recommendation Vitamin B12 (Cobalamine)
"Since most people with a high homocysteine level don't get enough folic acid, vitamin B6 or B12 in their diet, supplementing with these vitamins helps return homocysteine to normal levels..."

Female Infertility

Relationship to Increased Folic Acid Requirement
"Folic acid deficiency can lead to infertility..."

Folic Acid

As A Treatment
"...Although folic acid is found in vegetables, fruits, grain products, meat and meat alternatives, it is difficult to get the entire amount from food..."

Hepatitis

Recommendation Vitamin B12 (Cobalamine)
"Vitamin B12 (with or without folic acid) has been reported in studies from the 1950s to help some people with hepatitis..."

Recommendation Vitamin B-Complex
"B-complex (50 to 100mg per day), especially Folic Acid (800 to 1000mcg per day) and B12 (1000mcg per day) are needed for good liver function..."

Histadelia (Histamine High)

Recommendation against Folic Acid
"Histadelics should avoid supplemental folic acid as it can produce excess histamine..."

Histapenia (Histamine Low)

The Condition
"...Treatment & PreventionThe treatment program consists of the administration of zinc, manganese, vitamin C, niacin, vitamin B12, and folic acid..."

Recommendation Folic Acid
"The rationale underlying this treatment is that folic acid in conjunction with vitamin B12 injections raises the blood histamine while lowering the degree of symptoms..."

Ileum

Related Topic
"...The last foot of the ileum is the only absorption site available for important dietary substances such as vitamin B12, folic acid, some essential fatty acids, fat soluble vitamins, and recycled bile acids..."

Increased Folic Acid Requirement

The Condition
"Folic acid deficiency is one of the most common of all vitamin deficiencies..."

Our Question about birth control pill use
"Birth control pills reduce the folic acid content in the body..."

Relationship to Osteoporosis - Osteopenia
"Folate (folic acid) and the B-vitamins involved in homocysteine conversion (such as B12 and B6) may be beneficial in reducing the risk of osteoporosis because high levels of homocysteine are implicated in..."

Relationship to Acute Lymphocytic Leukemia (ALL)
"Maternal folic acid supplementation during pregnancy was associated with a reduced risk of acute lymphoblastic leukemia in children in a study in Western Australia..."

Recommendation Folic Acid
"Whether or not a woman is expecting a child, it is recommended that women of child-bearing age take folic acid every day in order to help prevent NTDs..."

Increased Legume Consumption

As A Treatment
"...They are an excellent source of fiber, protein, iron, folic acid, and other B vitamins..."

Inositol

As A Treatment
"...Vitamin E, vitamin C as well as folic acid and linoleic acid are thought to increase the functioning of inositol..."

Intestinal Malabsorption Syndrome

The Condition
"...Specific causes -- of which there are many -- lead to different patterns in malabsorption, involving for example fat and fat-soluble vitamins (A, D, E and K), vitamin B12, folic acid, iron, protein or carbohydrates..."

Liver Detoxification Phase II Support

As A Treatment
"...The lipotropic agents, choline, betaine, methionine, vitamin B6, folic acid, and vitamin B12, are useful as they promote the flow of fat and bile to and from the liver..."

Megaloblastic Anemia / Pernicious Anemia

The Condition
"...Megaloblastic anemias are usually caused by a deficiency or defective absorption of either vitamin B12 (cobalamin) or folic acid..."

Recommendation Test Folic Acid Levels
"Prevention of folic acid deficiency anemia involves eating raw or lightly-cooked vegetables every day..."

Recommendation Rest
"A person with folic acid deficiency anemia should rest as often as necessary until restored energy levels make it possible to resume regular activities..."

Recommendation Test for B12 Levels
"...When testing facilities are not available or cannot be afforded, intramuscular or sublingual B12, with or without folic acid, can be used to see if symptoms improve..."

Metabolic Diet Type

The Condition
"...Nutrients to De-emphasize: Potassium, Magnesium, Chromium, Copper, Iron, Manganese, Silicone, Boron, Vitamins B1, B2, B3, B6, C, D, Paba, biotin, and Folic acid..."

Osteoporosis - Osteopenia

Recommendation Folic Acid
"Folate (folic acid) and the B-vitamins involved in homocysteine conversion (such as B12 and B6) may be beneficial in reducing the risk of osteoporosis because high levels of homocysteine are implicated in..."

Pregnancy-Related Issues

The Condition
"..... Folic Acid Is Critical..."

Recommendation Folic Acid
"...This is often not met by the diets of pregnant women, so a supplement of 400mcg to 1mg per day of folic acid is recommended throughout pregnancy..."

Recommendation Vitamin B-Complex
"Many naturopathic and other doctors suggest using vitamin B complex (50mg per day) with additional vitamin B6 and folic acid (800 to 1000mcg per day) for women planning to become pregnant and for those who are pregnant..."

Probiotics

As A Treatment
"...Probiotics also make certain vitamins needed by the body including folic acid, vitamin B6, niacin and vitamin K..."

Restless Leg Syndrome

Relationship to Increased Folic Acid Requirement
"See the treatment link between RLS and folic acid..."

Recommendation Folic Acid
"...), you may respond very well to extra folic acid and B12, as well as a product high in specific nutrients that strengthen and elasticize the vessel walls..."

Schizophrenia

The Condition
"...Well-known causes ... Folic acid/B12 deficiency..."

Sickle Cell Trait / Disease

The Condition
"...The following are general guidelines to keep the sickle cell patient healthy ... Taking oral supplements of the vitamin folic acid (folate) daily to help make new red cells..."

Stinging Nettle

As A Treatment
"...These small sac-like structures contain amines such as histamine, as well as folic acid..."

Stomach Cancer

Recommendation Plant-Based Nutrition
"...The researchers found that plant-based nutrients such as dietary fiber, dietary beta-carotene, folic acid, vitamin C and vitamin B6 were associated with lower risk of these kinds of cancers..."

Stroke

Recommendation Folic Acid
"A study found that people with a dietary intake of at least 300mcg per day of folic acid reduced their risk of stroke and heart disease by 20% and 13% respectively, compared with those who consumed less than 136mcg of folic acid per day..."

Susceptibility To Miscarriages

The Condition
"...Nutritional lack of vitamins B6, B12 and folic acid aggravate the problem..."

Recommendation CoQ10 (Ubiquinone)
"...Similar to methionine and homocysteine normalization, the production of coenzyme Q10 in the body also depends on folic acid, vitamin B12, and betaine..."

Syndrome X

Recommendation Folic Acid
"Folic acid helps break down protein and may reduce the risk of heart disease..."

Test Folic Acid Levels

As A Treatment
"Serum folate (folic acid) is a test that is commonly used to monitor folic acid status..."

TMG (Tri-methyl-glycine)

As A Treatment
"...In one study, daily treatment with TMG, folic acid and choline normalized homocysteine levels in 17 of 19 patients..."

Tryptophan / 5HTP

As A Treatment
"...Vitamin B6 and folic acid may assist in the conversion to serotonin..."

Vitamin B12 (Cobalamine)

As A Treatment
"...It facilitates the cyclic metabolism of folic acid, which is essential for thymidine (one of the four DNA bases) synthesis..."

Vitamin B6 (Pyridoxine)

As A Treatment
"...The recent understanding of the use of B6 (as well as folic acid) in the reduction of high homocysteine levels (an independent risk factor for cardiovascular disease) can also be added to the benefits of P5P..."

Vitamin B-Complex

As A Treatment
"...B-vitamins are part of a family that includes thiamin (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folic acid (B9) and cobalamin (B12)..."

Vitamin B-Complex Requirement

The Condition
"...The eight vitamins are thiamine (B1), riboflavin (B2), niacin (B3), pyridoxine (B6), cobalamine (B12), folic acid, pantothenic acid and biotin..."

Vitiligo

Recommendation Vitamin B12 (Cobalamine)
"Because many people with vitiligo also have stomach malfunction, they do not absorb vitamin B12 and folic acid very well..."

Weakened Immune System

The Condition
"...We need extra folic acid as well..."

Wernicke-Korsakoff

Related Topic
"...About 40 percent of those affected also have anemia as a result of folic acid deficiency..."

Wernicke-Korsakoff syndrome

The Condition
"...About 40% of those affected also have anemia as a result of folic acid deficiency..."





Last updated: Aug 15, 2009


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