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Glossary: Pernicious Anemia
 


Definition
Anemia caused by a vitamin B12 deficiency.

Topics Related To Pernicious Anemia
Addison's DiseaseThe Condition
"...Less commonly associated auto-immune diseases are insulin-dependent diabetes mellitus, and insufficiencies of the parathyroid glands, gonads, and vitamin B12 absorption (pernicious anemia)..."

Atrophic Gastritis

Relationship to Stomach Cancer
"Gastric cancer is 5 to 10 times more likely in those with chronic atrophic gastritis; the same increased incidence is also found in first-degree relatives of patients with gastric cancer and pernicious anemia..."

Relationship to Megaloblastic Anemia / Pernicious Anemia
"...Patients with antibodies to parietal cells (PCA) or intrinsic factor, or both, have atrophy of the fundal mucosa (Type A) and a very high rate of pernicious anemia, often associated with other autoimmune endocrine disorders..."

CBC (Complete Blood Count) Test

As A Treatment
"...In some anemias, such as pernicious anemia, the amount of variation (anisocytosis) in RBC size (along with variation in shape - poikilocytosis) causes an increase in the RDW..."

Chronic Thyroiditis

Relationship to Megaloblastic Anemia / Pernicious Anemia
"Pernicious anemia is more common in people who have other autoimmune diseases such as thyroiditis..."

Cobalamin

Related Topic
"Essential for normal growth and functioning of all body cells, especially those of bone marrow (red blood cell formation), gastrointestinal tract and nervous system, it prevents pernicious anemia and plays a crucial part in the reproduction of every cell of the body i..."

Diabetes Type I

Relationship to Megaloblastic Anemia / Pernicious Anemia
"...The resulting inflammation and tissue damage reduces vitamin B12 absorption and may lead to Pernicious anemia, which occurs in approximately 1 in 50 adults with Type 1 Diabetes..."

Folic Acid

As A Treatment
"...With both folic acid deficiency anemia and pernicious anemia, folic acid is usually supplemented along with vitamin B12..."

Gastritis

The Condition
"...Laboratory Findings ... Macrocytic anaemia due to pernicious anemia following atrophic gastritis of long duration..."

Glossitis

The Condition
"...Causes & Development ... Disorders such as iron deficiency anemia, pernicious anemia and other B-vitamin deficiencies, oral lichen planus, erythema multiforme, aphthous ulcer, pemphigus vulgaris, syphilis, and others..."

Hypothyroidism

Relationship to Megaloblastic Anemia / Pernicious Anemia
"Pernicious anemia is associated with other autoimmune conditions such as Hashimoto's disease, a form of hypothyroidism..."

Low White Count

The Condition
"...Causes & Development Neutropenia can occur in acute bacterial infections, viral infections, rickettsiae disease, some parasite injections, aplastic and pernicious anemia, acute lymphoblastic leukemia, some hormone imbalances and anaphylactic shock..."

Megaloblast

Related Topic
"An abnormally large nucleated red blood cell found especially in people having pernicious anemia or certain vitamin deficiencies..."

Megaloblastic Anemia / Pernicious Anemia

The Condition
"...Eating extra yeast also seemed to relieve the symptoms of pernicious anemia, but the neurological symptoms of this disease either were not resolved or appeared later on, confirming some doctors' feelings that there were two different problems involved..."

Our Question about your serum iron level
"Elevated serum iron can occur as a result of pernicious anemia..."

Relationship to Vitamin B12 Requirement
"The main indicator of vitamin B12 deficiency is pernicious anemia, which in turn is due to a deficiency of intrinsic factor..."

Relationship to Schizophrenia
"Additional mental disturbances resulting from pernicious anemia include: loss of alertness, drive, self-confidence, and independence, social withdrawal, nervous irritability, headaches, insomnia, moodiness, severe agitation, lack of coordination,..."

Relationship to Alzheimer's Disease
"Pernicious Anemia can be mistaken for Alzheimer's in older patients..."

Multiple Sclerosis

Recommendation Test for B12 Levels
"...A vitamin B12 deficiency has very similar symptoms and is frequently misdiagnosed as MS; the type of anemia resulting from B12 deficiency is called pernicious anemia..."

Stiff Man Syndrome

The Condition
"...Other autoimmune disorders such as diabetes, pernicious anemia (a chronic, progressive blood disorder), and thyroiditis (inflammation of the thyroid gland) may occur more frequently in patients with stiff-person syndrome..."

Stomach Cancer

The Condition
"...Pernicious anemia - this affects the lining of the stomach..."

Test for B12 Levels

As A Treatment
"...Of pernicious anemia sufferers, 70% have these antibodies..."

Vitamin B12 (Cobalamine)

As A Treatment
"...In the early to mid 1800s, an unrecognized vitamin B12 deficiency was referred to as pernicious anemia because it was almost always fatal..."

Vitiligo

The Condition
"...Even though most people with vitiligo are in good general health, they are at greater risk of ... Pernicious anemia (vitamin B12 deficiency)..."





Last updated: Feb 28, 2008


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