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Glossary: Monoamine Oxidase
 


Definition
An enzyme catalyzing the removal of an amine group from a variety of substrates, including norepinephrine and dopamine. MAO inhibitors block the action of MAO, thus raising the levels of the monoamine neurotransmitters such as norepinephrine, epinephrine, dopamine, and serotonin - which have significant effects on mood and behavior. Epinephrine, norepinephrine and serotonin are normally deactivated by MAO-A while dopamine and phenylethylamine are normally metabolized by MAO-B.

Also: MAO

Topics Related To Monoamine Oxidase
Addictions / Addictive TendenciesThe Condition
"...Do not take L-Tyrosine if using a MAO inhibitor drug..."

Antidepressant

Related Topic
"Literally, substances meant to oppose depressions or sadness, and generally heterocyclic types such as Elavil, MAO inhibitors like phenelzine, or lithium carbonate..."

Depression

Relationship to Estrogens Low
"Low estrogen levels trigger the brain to release MAO, an enzyme in the brain which breaks down and destroys the neurotransmitter, serotonin..."

Hydrazine Sulfate

As A Treatment
"...WARNING! Hydrazine sulfate is a monoamine oxidase (MAO) inhibitor and is incompatible with tranquilizers, barbiturates, alcohol and other central nervous system depressants..."

Hypotension

The Condition
"...by any of the following ... Drug-induced, including alcohol toxicity, anesthesia, antianxiety agents, antihypertensives, calcium channel blockers, diuretics, general anesthetics, antiarrhythmics, monoamine oxidase inhibitors, narcotic analgesics, tranquilizers, vasodilators..."

Premenstrual Syndrome PMS A (Anxiety)

The Condition
"...Causes & Development Estrogens appear to affect mood by suppressing type A-monoamine oxidase (MAO) while enhancing type B-MAO..."

Schizophrenia

The Condition
"...Platelets deficient in MAO (monoamine oxidase)..."

Selegiline

As A Treatment
"...Selegiline blocks the enzyme monoamine oxidase type B, which forms one of the metabolic pathways for dopamine in the brain..."

St John's Wort

As A Treatment
"...In vitro experiments have detected MAO inhibition in extracts of Hypericum..."

Tyramine-containing Foods Avoidance

As A Treatment
"...The authors of this study concluded that pizzas from large chain commercial outlets are safe for consumption with MAO inhibitors..."

Weight Loss

As A Treatment
"...Also, your healthcare professional needs to be aware of any other medications you are taking or have taken within the last 14 days, especially monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil)..."





Last updated: Feb 28, 2008


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