"...Signs include mottled brown skin, hyperkeratosis (increased pigmentation) of palms and soles, cutis edema, transverse striate Leukonychia, perforation of nasal septum, eyelid edema, coryza, limb paralysis and reduced deep tendon..."

"Glycolic acid can be used to treat both seborrheic keratosis, actinic keratosis and hyperkeratosis..."

"...Penis: Pink macules or plaques on penis Large joints: Hyperkeratosis over elbows, knees, and ankles Tongue: Geographic tongue (rare) Pruritus may be present..."