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Glossary: DHEA
 


Definition
Dehydroepiandrosterone (DHEA) is a steroid produced by the adrenal glands and is the most abundant one found in humans. DHEA may be transformed into testosterone, estrogen or other steroids. It is found in the body as DHEA or in the sulfated form known as DHEA-S. One form is converted into the other as needed.

Also: DHEA-S

Topics Related To DHEA
Andropause/Male MenopauseThe Condition
"...Testosterone (from the testes), human growth hormone (from the pituitary), and DHEA and androstenedione (from the adrenal gland) levels all begin to drop..."

Recommendation DIM (di-indolmethane)/I3C (Indole-3-Carbinol)
"...Accumulation of estrogen during andropause is amplified by obesity since fat tissue is the site of conversion of both testosterone and DHEA into estrogen..."

Arrhythmias/Dysrhythmias

Recommendation against DHEA
"Ray Sahelian, MD has reported arrhythmias of different types in individuals using as little as 50mg DHEA or 25mg Pregnenolone..."

Atherosclerosis

Relationship to Low DHEA Level
"Although there is some conflicting evidence, many researchers conclude that maintaining normal levels of DHEA provides some protection against atherosclerosis..."

Autoimmune Tendency

Recommendation Test for DHEA
"Some doctors report finding that a high percentage of patients with autoimmune disorders are also deficient in DHEA, and should be tested..."

Breast Cancer

Recommendation Test for DHEA
"...Most of the 27 had abnormally low levels of DHEA..."

Chronic Fatigue / Fibromyalgia Syndrome

The Condition
"...DHEA and 7-Keto DHEA may be useful; routine endocrine tests are normal in suspected cases of fibromyalgia..."

Chronic Thyroiditis

Recommendation DHEA
"Some doctors report finding that a high percentage of patients with autoimmune disorders, such as thyroiditis, are also deficient in DHEA, and should be tested..."

Coronary Disease / Heart Attack

Recommendation DHEA
"A landmark study in 1986 of 242 men aged 50-79 and based on 12 years of research stated that a small supplementation of DHEA corresponded to a 48% reduction in death from heart disease and a 36% reduction in death from any cause, other than accidents..."

Depression

Recommendation DHEA
"DHEA is a plentiful adrenal steroid hormone whose quantity decreases with age and may have significant psychiatric effects..."

DHA (docosahexaenoic acid)

As A Treatment
"...DHA is an omega-3 long chain polyunsaturated fatty acid (not to be confused with the hormone DHEA)..."

DHEA

As A Treatment
"...DHEA is a hormone produced by the adrenal glands..."

DHEA Elevated

The Condition
"Excess DHEA can cause excess levels of estrogen and testosterone, as well as creating a dependence..."

Our Question about age at puberty onset (female)
"Girls with premature puberty have been found to have elevated levels of DHEA-S..."

Elevated Insulin Levels

Our Question about age at puberty onset (female)
"Girls with premature puberty have been found to have elevated insulin and DHEA-S levels..."

Erectile Dysfunction (ED, Impotence)

Recommendation Test for Hormones
"...When considering lab testing, a full panel of tests should be considered such as DHEA, testosterone (total and free), DHT, sex hormone binding globulin (SHBG), estradiol, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (best taken at 9am to avoid diurnal..."

Female Hair Loss

Recommendation Test for Hormones
"There have been several reports that supplemental DHEA has accelerated hair loss in susceptible men and women..."

Hepatitis

The Condition
"...enhanced by natural products or drugs such as IP6 (Inositol hexaphosphate), MGN3 (a commercial rice bran product modified with mushroom extracts), thymus extracts, low dose Naltrexone, zinc, DHEA, glutamine, a good multiple vitamin-mineral over time and others such as astragalus, cordyceps (chinese fungus), and MCP (modified citrus pectin)..."

Hirsutism

The Condition
"...DHEA or testosterone), most have normal levels..."

Hormones

Related Topic
"...Examples include adrenal hormones such as corticosteroids and aldosterone; glucagon, growth hormone, insulin, testosterone, estrogens, progestins, progesterone, DHEA, melatonin, and thyroid hormones such as thyroxine and calcitonin..."

Hyperthyroidism

Recommendation Test for DHEA
"Some doctors report finding that a high percentage of patients with autoimmune disorders, such as Graves' disease, are also deficient in DHEA, and should be tested..."

Hypoglycemia

Relationship to Low DHEA Level
"Insulin levels may play a significant role in determining how much DHEA is metabolized..."

Hypopituitarism

Recommendation DHEA
"Six months of treatment with DHEA (at 30mg per day if over 45 years of age and 20mg per day if under 45 years of age) induced androgen effects on skin and axillary and pubic hair in a study of 38 women with androgen deficiency due..."

Hypothyroidism

Recommendation Test Adrenal Function
"Cortisol and DHEA are among the hormones produced by the adrenal glands..."

Immune System Imbalance (TH2 Dominance)

The Condition
"...Ginseng extract), chlorella (spirulina and some other sea vegetables may have similar benefits), thyroid hormones, garlic (raw or aged extract), l-Glutathione (or products that raise levels), DHEA or AED (androstendiol), UV-A light, vitamin E, transfer factor (antigen specific) - protein immunomodulators extracted from colostrum, colostrum, low dose naltrexone, IP6, lentinian and certain..."

Recommendation DHEA
"DHEA increases TH1 cytokines which help balance the immune system..."

Low Adrenal Function / Adrenal Insufficiency

The Condition
"...hydrocortisone), mineralocorticoids (aldosterone) and androgens such as androstenedione and DHEA..."

Low DHEA Level

The Condition
"Produced by the adrenal glands, DHEA (Dehydroepiandrosterone) is mildly androgenic..."

Recommendation DHEA
"The optimal dosage range for DHEA varies considerably between individuals..."

Low Sex Drive

Relationship to Low DHEA Level
"DHEA is the precursor to testosterone..."

Low T-Helper (CD4) Cell Level

Recommendation DHEA
"One study has found that DHEA therapy (75mg per day) increased CD4 and CD8 cell counts in the majority of HIV patients..."

Lupus, SLE (Systemic Lupus Erythromatosis)

Relationship to Low DHEA Level
"Low blood levels of the hormone DHEA have been associated with more severe symptoms in people with SLE..."

Recommendation Test for DHEA
"DHEA is almost always low in patients with autoimmune conditions such as SLE..."

Male Hair Loss

Recommendation Test for Hormones
"There have been several reports that supplemental DHEA has accelerated hair loss in susceptible men and women..."

Menopausal Issues

Relationship to Syndrome X
"...With reduced SHBG levels, greater amounts of bioactive "male" sex hormones - androgens such as testosterone and DHEA - begin to circulate inside a woman's body..."

Myasthenia Gravis

Recommendation Test for DHEA
"DHEA is almost always low in patients with autoimmune conditions such as myasthenia gravis..."

Parkinson's Disease

Recommendation DHEA
"...has reported excellent success in treating Parkinson's Disease by use of replacement therapy of DHEA..."

Polycystic Ovary Syndrome (PCOS)

The Condition
"...When DHEA-S levels are elevated, the addition of dexamethasone may be helpful..."

Recommendation Test for Hormones
"...It is for this reason that a measurement of total testosterone and DHEA is recommended..."

Poor Memory

Recommendation DHEA
"In a study of six middle-aged and elderly patients with major depression and low plasma DHEA levels, memory performance and depression improved significantly when DHEA was supplemented sufficiently to raise their plasma DHEA to levels found in healthy younger people [Biol Psychiatry, 1997..."

Premature/Signs of Aging

Recommendation Test for Hormones
"...The hormones most likely to be involved include estrogens, progesterone, testosterone and DHEA..."

Problems Caused By Being Overweight

Recommendation DHEA
"7-Keto DHEA supplements, at a dose of 200mg per day in adults 25 to 55 years of age has been shown in a double-blind trial to enhance weight loss, aid in the reduction of body fat and effect thyroid hormone..."

Rheumatoid Arthritis

Relationship to Low DHEA Level
"DHEA levels have been found to be low in women with rheumatoid arthritis, a condition frequently associated with osteoporosis..."

Recommendation DHEA
"...DHEA levels correlated significantly with, and were predictive of, bone mineral density, even after corticosteroid therapy was taken into account..."

Stress

Relationship to Low DHEA Level
"Stress accelerates the loss of DHEA..."

Test for DHEA

As A Treatment
"Although not yet formally validated, DHEA testing can be performed on blood, saliva or urine samples..."

Test for Hormones

As A Treatment
"Hormone testing for sex hormones such as estrogens, progesterone, testosterone, DHEA, LH, FSH, prolactin and binding globulins (SHBG) is an important step in determining hormone abnormalities that may be causing or contributing to symptoms..."

Ulcerative Colitis

Recommendation Test for DHEA
"DHEA can be a factor in autoimmune problems, which some consider ulcerative colitis to be..."

Weakened Immune System

The Condition
"...food and other allergens, and being well-nourished; supplements such as TMG, zinc, vitamin C and other antioxidants; hormones such as HGH (human growth hormone - can be used homeopathically) and DHEA; colloidal silver, and l-arginine..."





Last updated: Oct 08, 2008


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