Spherocytosis

Definition of Spherocytosis:

A disease of the blood characterized by the production of red blood cells (erythrocytes), that are sphere-shaped, rather than donut-shaped.  It is caused by a molecular defect in one or more of the proteins of the red blood cell cytoskeleton.  Because the cell skeleton has a defect, the blood cell contracts to its most surface-tension efficient and least flexible configuration, a sphere, rather than the more flexible donut-shape.  The sphere-shaped red blood cells are known as spherocytes.

Also: Spherocytes

Topics Related to Spherocytosis

CBC (Complete Blood Count) Test

...as a treatment
“...Increased MCHC values (hyperchromia) are seen in conditions where the hemoglobin is abnormally concentrated inside the red cells, such as in hereditary spherocytosis, a relatively rare congenital disorder...”

Hemolytic Anemia

...the condition
“...Congenital Hemolytic Anemia is a general term for hemolytic anemia that is present from birth and in which the lifespan of red blood cells is diminished, such as occurs in hereditary spherocytosis...”

Hyperbaric Oxygen

...as a treatment
“...Upper respiratory infection – Increased hemolysis; Hyperthermia; Hereditary spherocytosis; Optic neuritis – Possible increased optic nerve pathology; Malignant tumors – possible increased vascularity for tumors; Acidosis – Decreased threshold for oxygen seizures; Steroid use...”
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