Platelet Aggregation

Definition of Platelet Aggregation:

Platelets are the small, rather uniform fragments of large bone marrow cells that aid the blood in coagulation, hemostasis, inflammation, and thrombus formation.  Mild subclotting and sticking is a common early condition that can lead to thrombosis, atherosclerosis, and strokes, and can be helped by an aspirin a day, better fat digestion, and Ceanothus.

Topics Related to Platelet Aggregation

A Low Platelet Count

...recommendation Vitamin E
“...[Science 163: 762, 1946)] Note, however, that vitamin E is known to increase bleeding tendency by reducing platelet aggregation, so higher doses may be contraindicated for some patients...”

Alcohol Consumption

...as a treatment
“...Function; Why it is Recommended: Why would explain the apparent benefits of alcohol consumption? ... Alcohol decreases risk of thrombosis (blood clotting) by reducing platelet aggregation and fibrinogen (a blood clotter), and increasing fibrinolysis (the process by which clots dissolve);...”
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More topics Related to Platelet Aggregation

Angina

...the condition
“...Causes and Development: The primary cause is atherosclerosis, although platelet aggregation, coronary artery spasm, myocardial ischemia, non-vascular mechanisms such as hypoglycemia, and increased metabolic need (as in hyperthyroidism) can also be important...”
...recommendation Garlic
“...This increased fibrinolytic activity inhibits platelet aggregation which contributes to the formation of blood clots...”

Atherosclerosis

...recommendation Garlic
“...Garlic, ginger and onions all have a beneficial effect on platelet aggregation which reduces the tendency to form clots too easily, thus preventing the blockage of narrowed arteries...”
...recommendation Bromelain
“...Inhibits platelet aggregation and breaks down plaque...”

Bilberry

...as a treatment
“...The actions of concentrated extracts have been shown to be effective in stabilizing collagen, normalizing capillary permeability, preventing platelet aggregation, and relaxing smooth muscles among other things...”

Bleeding Tendency

...the condition
“...All investigated causes being absent, you should avoid large quantities of those supplements that reduce platelet aggregation and promote easier bleeding, especially when using any blood-thinning medication...”

Bromelain

...as a treatment
“...Other activities associated with bromelain include inhibition of platelet aggregation, decreasing the viscosity of mucus (mucolytic), antibiotic activity and smooth muscle relaxant...”

Evening Primrose Oil

...as a treatment
“...GLA has been shown to inhibit platelet aggregation and reduce blood pressure...”

Ginkgo Biloba

...as a treatment
“...Ginkgolide-B is a known inhibitor of Platelet Activating Factor (PAF), which is responsible for platelet aggregation, PAF-induced asthma and various inflammatory and pro-oxidative processes...”

Guaifenesin

...as a treatment
“...Guaifenesin also has other known neurological effects, including an analgesic effect that is related to its action as a skeletal muscle relaxant, and it may inhibit platelet aggregation...”

Gugulipids

...as a treatment
“...Gugulipid has also been shown to decrease platelet aggregation and increase fibrinolytic activity in patients with coronary artery disease...”

Magnesium

...as a treatment
“...Capable of preventing arrhythmias (heart beat irregularity), magnesium has been shown to cut platelet aggregation (blood stickiness) and avert spasm of the coronary arteries...”

Mitral Valve Prolapse

...recommendation Magnesium
“...A magnesium deficiency ... increases circulating catecholamines (an important mediator in platelet aggregation),...”

Onion

...as a treatment
“...Other activities associated with onions are lowering blood pressure (via decreased platelet aggregation), general antibiotic activity and various conditions of the gastrointestinal tract...”

Phlebitis / Thrombophlebitis

...recommendation Bromelain
“Due to its anti-inflammatory properties and ability to prevent blood platelet aggregation, bromelain has been suggested as a treatment for phlebitis...”

Platelet Aggregation (Clotting)

...the condition
“...They play a major role in the blood-clotting process; platelet aggregation is a crucial step in the process of clot formation, which stops bleeding...”
...relationship to Atherosclerosis
“Excessive platelet aggregation has been linked with the development of atherosclerosis and other cardiovascular conditions...”
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More topics Related to Platelet Aggregation

Stroke

...recommendation EPA (eicosapentanoic acid)
“EPA reduces platelet aggregation and thus helps prevent those strokes that are due to an abnormal clotting tendency...”
...recommendation Vitamin B6 (Pyridoxine)
“Vitamin B6 at 150-200mg daily reduces platelet aggregation, and thus may help prevent ischemic (clotting type) strokes...”
...recommendation Cayenne Pepper
“Cayenne reduces platelet aggregation (makes the blood less likely to clot) and thus may reduce the risk of clotting strokes...”
...recommendation Turmeric Extract, Curcumin
“Reduces platelet aggregation...”
...recommendation Essential Fatty Acids
“High doses of Omega-3 oils reduce platelet aggregation and thus reduce the abnormal clotting tendency which is seen in 75% of strokes...”
...recommendation Garlic
“Reduces platelet aggregation...”
...recommendation Ginkgo Biloba
“Reduces platelet aggregation...”
...recommendation Gugulipids
“Reduces platelet aggregation and promotes fibrinolysis (clot breakdown)...”
...recommendation Policosanol/Octacosanol
“...In a comparison of aspirin and policosanol, aspirin was better at reducing one type of platelet aggregation (clumping together of blood cells) but policosanol was better at inhibiting another type...”
...recommendation Testosterone
“Reduces platelet aggregation...”
...recommendation Vitamin E
“Vitamin E at 300 IU or above reduces platelet aggregation, as do the tocotrienols...”
...recommendation L-Taurine
“Taurine reduces platelet aggregation, which is how most natural products work in stroke prevention...”

Turmeric

...as a treatment
“...Turmeric (curcumin) has been shown to have anti-inflammatory, antioxidant, cholesterol-lowering, platelet aggregation inhibition, hepatoprotective, carminative, and antimicrobial activities...”

Ultraviolet Light Therapy

...as a treatment
“...UVB therapy is used to ... decrease platelet aggregation...”

Vasculitis

...the condition
“...Vasoactive amines cause increased vessel permeability, platelet aggregation (clotting) and initiation of the arachidonic acid cascade (inflammation)...”
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